KERA | ENSG00000139330 | NCBI 11081

Details for: KERA

Gene ID: 11081

Symbol: KERA

Ensembl ID: ENSG00000139330

Description: keratocan

Associated with

Defective b4galt1 causes b4galt1-cdg (cdg-2d)
(R-HSA-3656244)
Defective chst6 causes mcdc1
(R-HSA-3656225)
Defective st3gal3 causes mct12 and eiee15
(R-HSA-3656243)
Disease
(R-HSA-1643685)
Diseases associated with glycosaminoglycan metabolism
(R-HSA-3560782)
Diseases of glycosylation
(R-HSA-3781865)
Diseases of metabolism
(R-HSA-5668914)
Glycosaminoglycan metabolism
(R-HSA-1630316)
Keratan sulfate/keratin metabolism
(R-HSA-1638074)
Keratan sulfate biosynthesis
(R-HSA-2022854)
Keratan sulfate degradation
(R-HSA-2022857)
Metabolism
(R-HSA-1430728)
Metabolism of carbohydrates
(R-HSA-71387)
Cornea development in camera-type eye
(GO:0061303)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi lumen
(GO:0005796)
Lysosomal lumen
(GO:0043202)
Molecular_function
(GO:0003674)
Response to stimulus
(GO:0050896)
Visual perception
(GO:0007601)

Other Information

Proteins

Keratocan

Genular Protein ID: 2173597130

Symbol: KERA_HUMAN

Name: Keratocan

UniProtKB Accession Codes:

O60938

Database IDs:

Citations:

PubMed ID: 10565548

Title: Structure and sequence of the gene encoding human keratocan.

PubMed ID: 10565548

DOI: 10.3109/10425179909033939

PubMed ID: 10802664

Title: Mutations in KERA, encoding keratocan, cause cornea plana.

PubMed ID: 10802664

DOI: 10.1038/75664

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11683372

Title: Keratocan expression is increased in the stroma of keratoconus corneas.

PubMed ID: 11683372

DOI: 10.1007/bf03401852

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 11726611

Title: A novel keratocan mutation causing autosomal recessive cornea plana.

PubMed ID: 11726611

Sequence Information:

Length: 352
Mass: 40509
Checksum: 0CF8DEC938852D28
Sequence:

MAGTICFIMW VLFITDTVWS RSVRQVYEVH DSDDWTIHDF ECPMECFCPP SFPTALYCEN 
RGLKEIPAIP SRIWYLYLQN NLIETIPEKP FENATQLRWI NLNKNKITNY GIEKGALSQL 
KKLLFLFLED NELEEVPSPL PRSLEQLQLA RNKVSRIPQG TFSNLENLTL LDLQNNKLVD 
NAFQRDTFKG LKNLMQLNMA KNALRNMPPR LPANTMQLFL DNNSIEGIPE NYFNVIPKVA 
FLRLNHNKLS DEGLPSRGFD VSSILDLQLS HNQLTKVPRI SAHLQHLHLD HNKIKSVNVS 
VICPSPSMLP AERDSFSYGP HLRYLRLDGN EIKPPIPMAL MTCFRLLQAV II

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: KERA

Associated with

Other Information

Structure and sequence of the gene encoding human keratocan. PubMed ID: 10565548

Mutations in KERA, encoding keratocan, cause cornea plana. PubMed ID: 10802664

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Keratocan expression is increased in the stroma of keratoconus corneas. PubMed ID: 11683372

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952