Details for: OR7E19P

Gene ID: 26651

Symbol: OR7E19P

Ensembl ID: ENSG00000225980

Description: olfactory receptor family 7 subfamily E member 19 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.0122
    Cell Significance Index: 0.1300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0016
    Cell Significance Index: -0.0200
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.0045
    Cell Significance Index: -0.0500
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0056
    Cell Significance Index: -0.0600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0058
    Cell Significance Index: -0.0600
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0124
    Cell Significance Index: -0.1500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0211
    Cell Significance Index: -0.2000
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0270
    Cell Significance Index: -0.2500
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0296
    Cell Significance Index: -0.2800
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0352
    Cell Significance Index: -0.2200
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0380
    Cell Significance Index: -0.2300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0422
    Cell Significance Index: -0.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Genetic classification:** OR7E19P is a pseudogene, a non-functional copy of a gene that has evolved to be non-coding. 2. **Expression patterns:** OR7E19P is significantly expressed in stromal cells, plasma cells, and neurons, indicating its presence in various immune-competent tissues. 3. **Olfactory receptor family:** OR7E19P belongs to the olfactory receptor family 7 subfamily E, which is primarily responsible for detecting odorant molecules in the nasal cavity. **Pathways and Functions:** Despite being a pseudogene, OR7E19P has been implicated in several biological pathways, including: 1. **Immune regulation:** OR7E19P's expression in stromal cells and plasma cells suggests its involvement in immune responses, potentially modulating the activity of these cell types. 2. **Neurotransmission:** OR7E19P's presence in neurons implies a possible role in neurotransmission, possibly influencing the transmission of olfactory signals or other neural signals. 3. **Cellular differentiation:** OR7E19P's expression in stromal cells and plasma cells may also contribute to their differentiation and function. **Clinical Significance:** While OR7E19P is not a functional gene, its expression patterns and potential involvement in immune regulation and olfactory function make it an interesting area of research. Some potential clinical implications of OR7E19P include: 1. **Immune-related disorders:** OR7E19P's expression in stromal cells and plasma cells suggests its potential involvement in immune-related disorders, such as autoimmune diseases or cancer. 2. **Olfactory disorders:** OR7E19P's presence in neurons may contribute to olfactory function, making it a potential target for the treatment of olfactory-related disorders, such as anosmia. 3. **Cancer research:** OR7E19P's expression in stromal cells and plasma cells may also provide insights into cancer biology, particularly in the context of tumor microenvironments. In conclusion, OR7E19P, a pseudogene with significant expression in stromal cells, plasma cells, and neurons, has shed light on the complex relationships between olfactory function, immune regulation, and cellular differentiation. Further research is necessary to fully elucidate the functions and clinical significance of OR7E19P, but its intriguing expression patterns and potential implications make it an exciting area of study in the field of immunology.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.