PRODH2 | ENSG00000250799 | NCBI 58510

Details for: PRODH2

Gene ID: 58510

Symbol: PRODH2

Ensembl ID: ENSG00000250799

Description: proline dehydrogenase 2

Associated with

Glyoxylate metabolism and glycine degradation
(R-HSA-389661)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Proline catabolism
(R-HSA-70688)
Fad binding
(GO:0071949)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrion
(GO:0005739)
Oxidoreductase activity, acting on the ch-nh group of donors
(GO:0016645)
Proline catabolic process
(GO:0006562)
Proline catabolic process to glutamate
(GO:0010133)
Proline dehydrogenase activity
(GO:0004657)

Other Information

Proteins

Kidney and liver proline oxidase 1

Genular Protein ID: 3405147302

Symbol: HYPDH_HUMAN

Name: Kidney and liver proline oxidase 1

UniProtKB Accession Codes:

Q9UF12 A0A590UKC3

Database IDs:

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 25697095

Title: Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria.

PubMed ID: 25697095

DOI: 10.1042/bj20141159

Sequence Information:

Length: 460
Mass: 50898
Checksum: 1CE20EC9778D86E3
Sequence:

MLRTCYVLCS QAGPPSRGWQ SLSFDGGAFH LKGTGELTRA LLVLRLCAWP PLVTHGLLLQ 
AWSRRLLGSR LSGAFLRASV YGQFVAGETA EEVKGCVQQL RTLSLRPLLA VPTEEEPDSA 
AKSGEAWYEG NLGAMLRCVD LSRGLLEPPS LAEASLMQLK VTALTSTRLC KELASWVRRP 
GASLELSPER LAEAMDSGQN LQVSCLNAEQ NQHLRASLSR LHRVAQYARA QHVRLLVDAE 
YTSLNPALSL LVAALAVRWN SPGEGGPWVW NTYQACLKDT FERLGRDAEA AHRAGLAFGV 
KLVRGAYLDK ERAVAQLHGM EDPTQPDYEA TSQSYSRCLE LMLTHVARHG PMCHLMVASH 
NEESVRQATK RMWELGIPLD GTVCFGQLLG MCDHVSLALG QAGYVVYKSI PYGSLEEVIP 
YLIRRAQENR SVLQGARREQ ELLSQELWRR LLPGCRRIPH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.