Details for: RN7SL271P

Gene ID: 106479321

Symbol: RN7SL271P

Ensembl ID: ENSG00000239250

Description: RNA, 7SL, cytoplasmic 271, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1643
    Cell Significance Index: 2.4300
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.0103
    Cell Significance Index: 0.1200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0031
    Cell Significance Index: -0.0300
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0038
    Cell Significance Index: -0.0500
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.0044
    Cell Significance Index: -0.0500
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0074
    Cell Significance Index: -0.0400
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0088
    Cell Significance Index: -0.0800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0114
    Cell Significance Index: -0.2500
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0120
    Cell Significance Index: -0.1000
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0218
    Cell Significance Index: -0.2000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RN7SL271P is classified as a pseudogene, which implies that it lacks the essential features of a functional gene, such as the ability to transcribe into a protein. Despite this, RN7SL271P is significantly expressed in multiple cell types, suggesting that it may play a non-transcriptional role or be involved in regulatory processes that do not require protein synthesis. The pseudogene nature of RN7SL271P is reinforced by its lack of evidence for protein-coding potential. **Pathways and Functions:** The functional significance of RN7SL271P remains unclear, but its widespread expression in various cell types suggests that it may be involved in cellular processes such as: 1. **Regulation of gene expression:** RN7SL271P may act as a non-coding RNA regulator, influencing the expression of nearby genes or participating in transcriptional programs. 2. **Cell signaling:** As a pseudogene, RN7SL271P may interact with signaling molecules or receptors, modulating cellular responses to external stimuli. 3. **Epigenetic regulation:** RN7SL271P could be involved in epigenetic modifications, such as DNA methylation or histone modification, which are crucial for maintaining cellular homeostasis. **Clinical Significance:** The clinical significance of RN7SL271P is an area of ongoing research, but preliminary findings suggest that alterations in RN7SL271P expression may be associated with: 1. **Neurological disorders:** RN7SL271P expression has been observed in neurons, raising the possibility that it may be involved in neurological diseases, such as neurodegenerative disorders or cancer. 2. **Intestinal diseases:** The expression of RN7SL271P in intestinal cells suggests that it may play a role in maintaining intestinal homeostasis, and alterations in its expression could contribute to intestinal disorders, such as inflammatory bowel disease. 3. **Cancer:** RN7SL271P expression has been observed in neoplastic cells, which may indicate that it has a role in tumorigenesis or cancer progression. In conclusion, RN7SL271P is a pseudogene with a complex expression profile that warrants further investigation. Its widespread expression in various cell types and potential involvement in regulatory processes, cell signaling, and epigenetic modifications make it an intriguing target for research. Further studies are needed to elucidate the functional significance of RN7SL271P and its clinical implications in human diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.