Details for: RNY3P7

Gene ID: 100862670

Symbol: RNY3P7

Ensembl ID: ENSG00000206800

Description: RNY3 pseudogene 7

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.0523
    Cell Significance Index: 14.9800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2570
    Cell Significance Index: -6.4200
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.3572
    Cell Significance Index: -4.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3601
    Cell Significance Index: -9.6500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4924
    Cell Significance Index: -10.7800
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.6385
    Cell Significance Index: -7.6000
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.7650
    Cell Significance Index: -8.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.7978
    Cell Significance Index: -10.8800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.0652
    Cell Significance Index: -13.4400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.1550
    Cell Significance Index: -12.5800
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -1.6874
    Cell Significance Index: -13.1300
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: -3.8381
    Cell Significance Index: -13.3500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNY3P7 is a pseudogene, meaning it lacks the coding potential to produce a functional protein. However, it is significantly expressed in various human tissues, suggesting that it may play a role in regulating gene expression or modulating cellular processes. The widespread expression of RNY3P7 across different cell types is striking, and it is essential to investigate the underlying mechanisms driving this phenomenon. **Pathways and Functions:** While RNY3P7 lacks coding potential, its expression in multiple cell types suggests that it may be involved in regulating gene expression through non-coding RNA-mediated mechanisms. One possible hypothesis is that RNY3P7 acts as a long non-coding RNA (lncRNA) or a microRNA (miRNA) precursor, which could influence gene expression by binding to specific mRNAs or transcription factors. The expression of RNY3P7 in stem cells, including intestinal crypt stem cells, also raises the possibility that it plays a role in maintaining cellular homeostasis and regulating cell fate decisions. **Clinical Significance:** The clinical significance of RNY3P7 is an area of ongoing research. Given its widespread expression in human tissues, RNY3P7 may be involved in various diseases, including cancer. For instance, its expression in neoplastic cells suggests that it may play a role in tumorigenesis or tumor progression. Additionally, the expression of RNY3P7 in intestinal epithelial cells and goblet cells raises questions about its involvement in gastrointestinal diseases, such as inflammatory bowel disease or colorectal cancer. Furthermore, the expression of RNY3P7 in corneal epithelial cells and brush cells suggests that it may be involved in ocular diseases, such as corneal disorders or conjunctivitis. As an immunologist, I would like to explore the potential role of RNY3P7 in modulating the immune response and its involvement in autoimmune diseases. In conclusion, while RNY3P7 is a pseudogene without coding potential, its widespread expression in human tissues suggests that it may play a role in regulating gene expression and modulating cellular processes. Further research is necessary to fully understand the mechanisms driving RNY3P7 expression and its clinical significance. As an immunologist, I believe that RNY3P7 is an intriguing gene that warrants further investigation and may hold secrets to understanding various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.