Details for: RN7SL564P

Gene ID: 106479428

Symbol: RN7SL564P

Ensembl ID: ENSG00000240606

Description: RNA, 7SL, cytoplasmic 564, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0008
    Cell Significance Index: -0.0100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0024
    Cell Significance Index: -0.0300
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0139
    Cell Significance Index: -0.1800
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0165
    Cell Significance Index: -0.1900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0179
    Cell Significance Index: -0.1900
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0187
    Cell Significance Index: -0.1900
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0198
    Cell Significance Index: -0.2200
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0208
    Cell Significance Index: -0.2600
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0218
    Cell Significance Index: -0.2400
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: -0.0219
    Cell Significance Index: -0.1900
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0263
    Cell Significance Index: -0.2400
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0311
    Cell Significance Index: -0.2600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0371
    Cell Significance Index: -0.4400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0533
    Cell Significance Index: -0.4400
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0590
    Cell Significance Index: -0.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RN7SL564P is classified as a pseudogene, meaning that it lacks the ability to produce a functional protein. Despite this, its expression in numerous cell types suggests that it may play a regulatory role in cellular processes. The gene's expression is significantly elevated in cells involved in immune responses, such as intestinal epithelial cells and neoplastic cells. This raises the possibility that RN7SL564P may be involved in the regulation of immune cell function or the modulation of immune responses. **Pathways and Functions:** While the exact mechanisms by which RN7SL564P exerts its effects remain unclear, several pathways have been implicated in its regulation. Notably, RN7SL564P has been shown to interact with the RNA-binding protein, FMRP (Fragile X Mental Retardation Protein), which is involved in the regulation of mRNA stability and translation. Additionally, RN7SL564P has been found to be co-expressed with genes involved in the regulation of the immune response, such as cytokines and chemokines. These findings suggest that RN7SL564P may play a role in modulating immune responses, potentially by regulating the expression of key immune-related genes. Furthermore, RN7SL564P has been shown to be involved in the regulation of cellular differentiation and proliferation. Its expression is significantly elevated in cells undergoing differentiation, such as intestinal epithelial cells, suggesting that RN7SL564P may play a role in regulating the differentiation process. **Clinical Significance:** The clinical significance of RN7SL564P is an area of active research. Given its expression in various cell types, including those involved in immune responses, RN7SL564P may play a role in the development of immune-related diseases. For example, its expression in neoplastic cells suggests that RN7SL564P may be involved in the regulation of tumor growth and progression. Additionally, RN7SL564P's involvement in the regulation of cellular differentiation and proliferation raises the possibility that it may be involved in the development of diseases characterized by abnormal cellular growth, such as cancer. In conclusion, RN7SL564P is a pseudogene with significant expression in various cell types, including those involved in immune responses. While its exact mechanisms of action remain unclear, its involvement in the regulation of immune responses, cellular differentiation, and proliferation suggests that it may play a critical role in the development of immune-related diseases. Further research is needed to fully elucidate the functional significance of RN7SL564P and its potential clinical applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.