Details for: GINS3

Gene ID: 64785

Symbol: GINS3

Ensembl ID: ENSG00000181938

Description: GINS complex subunit 3

Associated with

Other Information

Genular Protein ID: 3376924009

Symbol: PSF3_HUMAN

Name: DNA replication complex GINS protein PSF3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17170760

Title: The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase.

PubMed ID: 17170760

DOI: 10.1038/sj.embor.7400870

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 28414293

Title: Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.

PubMed ID: 28414293

DOI: 10.1172/jci90727

PubMed ID: 35585232

Title: Fast and efficient DNA replication with purified human proteins.

PubMed ID: 35585232

DOI: 10.1038/s41586-022-04759-1

PubMed ID: 17557111

Title: Molecular architecture of the human GINS complex.

PubMed ID: 17557111

DOI: 10.1038/sj.embor.7401002

PubMed ID: 17545466

Title: Crystal structure of the human GINS complex.

PubMed ID: 17545466

DOI: 10.1101/gad.1548107

PubMed ID: 17417653

Title: Structure of the human GINS complex and its assembly and functional interface in replication initiation.

PubMed ID: 17417653

DOI: 10.1038/nsmb1231

PubMed ID: 17652513

Title: Crystal structure of the GINS complex and functional insights into its role in DNA replication.

PubMed ID: 17652513

DOI: 10.1073/pnas.0705558104

PubMed ID: 32453425

Title: CryoEM structures of human CMG-ATPgammaS-DNA and CMG-AND-1 complexes.

PubMed ID: 32453425

DOI: 10.1093/nar/gkaa429

PubMed ID: 34700328

Title: A conserved mechanism for regulating replisome disassembly in eukaryotes.

PubMed ID: 34700328

DOI: 10.1038/s41586-021-04145-3

PubMed ID: 34694004

Title: Structure of a human replisome shows the organisation and interactions of a DNA replication machine.

PubMed ID: 34694004

DOI: 10.15252/embj.2021108819

Sequence Information:

  • Length: 216
  • Mass: 24535
  • Checksum: A1B264A72371C551
  • Sequence:
  • MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETAM PRLGAFFLER SAGAETDNAV 
    PQGSKLELPL WLAKGLFDNK RRILSVELPK IYQEGWRTVF SADPNVVDLH KMGPHFYGFG 
    SQLLHFDSPE NADISQSLLQ TFIGRFRRIM DSSQNAYNED TSALVARLDE MERGLFQTGQ 
    KGLNDFQCWE KGQASQITAS NLVQNYKKRK FTDMED

Genular Protein ID: 925861789

Symbol: A0A0S2Z5L4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 138
  • Mass: 15655
  • Checksum: 50D249B01A5F66EE
  • Sequence:
  • MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETAM PRLGAFFLER SAGAETDNAV 
    PQTFIGRFRR IMDSSQNAYN EDTSALVARL DEMERGLFQT GQKGLNDFQC WEKGQASQIT 
    ASNLVQNYKK RKFTDMED

Genular Protein ID: 3295555172

Symbol: A0A0S2Z5P2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 255
  • Mass: 28775
  • Checksum: 99614F114B6B6CF1
  • Sequence:
  • MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETAM PRLGAFFLER SAGAETDNAV 
    PQGFALLPRL ECSGVIWLTA ALTSQAPEIL PPQPPMWLVL QGSKLELPLW LAKGLFDNKR 
    RILSVELPKI YQEGWRTVFS ADPNVVDLHK MGPHFYGFGS QLLHFDSPEN ADISQSLLQT 
    FIGRFRRIMD SSQNAYNEDT SALVARLDEM ERGLFQTGQK GLNDFQCWEK GQASQITASN 
    LVQNYKKRKF TDMED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.