Details for: CL0000097

Cell ID: CL0000097

Cell Name: mast cell

CSI Thresholds:

Select Context Threshold
13.1600
1598.1912
1419.2347
645.2084
629.6681
259.4721
259.3789
168.9773
164.1150
162.2766
156.7949
156.1255
154.8573
153.8866
131.7202
127.4655
127.2028
126.3206
98.3932
98.2762
91.3006
85.5407
84.0763
82.1098
79.1401
78.0117
77.3244
75.5205
73.2106
73.1811
67.5014
67.0304
65.5514
64.1187
62.4314
61.2529
60.9624
55.0708
54.8594
54.5321
53.9237
53.6880
53.1009
52.1936
51.8841
51.3951
50.5096
50.4699
50.3034
48.5237
47.5177
46.5868
46.5340
46.4844
46.2202
46.2019
46.0360
46.0186
45.9495
45.9407
45.9340
45.7962
45.0582
44.8762
44.6983
43.8899
43.7642
43.6947
43.5791
43.5615
41.4849
41.0114
40.4378
39.8959
39.8728
39.7203
39.6002
39.3635
37.6441
37.6189
36.3528
36.3246
35.8449
35.7944
34.2874
33.9138
33.6636
32.3297
32.2075
31.9855
31.3591
31.2286
30.9565
30.9291
30.8697
30.8477
30.2047
30.1646
29.9659
29.9201
29.8751
29.8726
29.7785
29.1861
28.9794
28.5693
27.9151
27.5528
27.4767
27.4736
27.1978
26.8884
26.3511
24.6656
24.6622
24.3955
24.2350
23.7557
23.7024
23.6605
23.4908
23.3565
23.3293
23.2122
23.1370
22.9211
22.6726
22.6712
22.2522
22.1773
22.1365
22.1209
21.9111
21.8987
21.8781
21.3621
21.3546
21.3406
21.3288
21.1685
21.0034
20.9139
20.8432
20.7795
20.7551
20.7456
20.6923
20.6773
20.6421
20.4890
20.4660
20.3897
19.9794
19.6546
19.5921
19.3937
19.3748
19.3374
19.3371
19.1957
19.1913
19.0313
19.0209
18.9961
18.9935
18.8764
18.8383
18.8102
18.7260
18.6439
18.6111
18.5879
18.5380
18.4860
18.4578
18.4510
18.4057
18.3126
18.1423
18.0380
18.0367
18.0084
18.0056
17.8580
17.7490
17.7164
17.6658
17.4212
17.1499
17.1019
17.0653
17.0024
16.9887
16.7052
16.6224
16.3160
16.1392
16.0671
15.8799
15.8256
15.7795
15.6905
15.6669
15.6301
15.6228
15.5668
15.4881
15.4870
15.4360
15.4016
15.3157
15.3141
15.3005
15.1766
15.1265
15.0682
15.0439
15.0143
14.8643
14.6993
14.6493
14.6347
14.5368
14.5325
14.4957
14.4711
14.4317
14.2356
14.1916
14.1912
14.0487
14.0220
13.8866
13.5944
13.5886
13.3672
13.2384
13.0674
13.0255
12.6587
12.5667
12.3251
12.1173
12.0664
11.8925
11.6478
11.3550
11.1124
11.1084
10.9778
10.9591
10.8454
10.7709
10.7695
10.6738
10.6737
10.5391
10.4414
10.4244
10.4045
10.2238
10.2196
10.1262
10.0791
9.9277
9.8839
9.8421
9.7491
9.7258
9.4377
9.4327
9.3537
9.2462
9.2362
9.1890
9.1017
9.0844
9.0625
8.8426
8.7916
8.7907
8.7537
8.6995
8.6016
8.5891
8.4034
8.3906
8.3636
8.3018
8.2187
8.0866
8.0810
8.0788
7.9019
7.9016
7.6606
7.4741
7.4590
7.4214
7.4124
7.3575
7.2101
7.2011
7.1510
7.1243
7.0952
7.0361
7.0135
6.9193
6.8056
6.6487
6.5863
6.5681
6.5421
6.4940
6.4710
6.4559
6.4442
6.4323
6.3715
6.3695
6.3012
6.1986
6.1519
5.7337
5.7036
5.6088
5.5729
5.5440
5.5260
5.4893
5.4830
5.4703
5.4482
5.4133
5.3863
5.2553
5.2479
5.1919
5.1738
5.1274
5.0600
5.0409
5.0313
5.0148
4.9869
4.9734
4.8924
4.8542
4.8532
4.7911
4.7876
4.7092
4.6690
4.6365
4.5368
4.5193
4.5149
4.4353
4.3842
4.3217
4.2040
4.0927
4.0683
4.0542
4.0019
3.8931
3.8575
3.7852
3.7646
3.5301
3.4719
3.1808
3.1456
3.0305
2.7086
2.6159
2.4521
2.3733
2.3529
2.3365
2.3339
2.3142
2.2856
2.2432
2.2422
2.2322
2.0989
2.0755
2.0601
2.0416
1.9492
1.9389
1.9033
1.8848
1.8677
1.8506
1.8246
1.7207
1.7132
1.6957
1.6713
1.6702
1.5920
1.3814
0.6161
0.6042
0.4386
0.4360
0.4316
0.4007
-0.4777
-0.5463
-0.6101
-1.9658
-2.0093
-3.8714
-3.8874
-4.9742
-5.0617
-5.5364
-5.7068
-5.7228
-5.8713
-5.8940
-6.0886
-6.2429
-7.6913
-7.7248
-7.7429
-7.7862
-7.9025
-10.0671
-10.2899
-10.3942
-11.4230
-11.6921
-11.9435
-12.0219
-13.4768
-13.5688
-18.8257
-18.9065
-20.9108
-21.0100
-23.4616
-24.6301
-24.6466
-25.4605
-25.8210
-28.0920
-28.1409
-29.4085
-29.5531
-30.2516
-32.2315
-39.1889
-40.6216
-40.7445
-41.5901
-41.7524
-44.9411
-45.0241
-47.2769
-47.4548
-47.7132
-47.7195
-51.1952
-51.2106
-51.2688
-51.3467
-60.3573
-60.5832
-87.1582
-87.5795
-93.1709
-106.4080
-106.8829
-253.9737
-292.5441
(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.

Synonyms: histaminocyte, labrocyte, mastocyte, tissue basophil