Details for: RHAG

Gene ID: 6005

Symbol: RHAG

Ensembl ID: ENSG00000112077

Description: Rh associated glycoprotein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: basophilic erythroblast (CL0000549)
    Fold Change: 44.2682
    Cell Significance Index: 20.1600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 11.2757
    Cell Significance Index: -2.8600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.3434
    Cell Significance Index: 32.5400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.0491
    Cell Significance Index: 22.4300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5979
    Cell Significance Index: 413.5400
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.2880
    Cell Significance Index: 3.2600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.1961
    Cell Significance Index: 4.8900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1199
    Cell Significance Index: 3.0800
  • Cell Name: enucleate erythrocyte (CL0000595)
    Fold Change: 0.0889
    Cell Significance Index: 0.4600
  • Cell Name: reticulocyte (CL0000558)
    Fold Change: 0.0570
    Cell Significance Index: 0.3000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0549
    Cell Significance Index: 0.9400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0345
    Cell Significance Index: 0.5800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.0148
    Cell Significance Index: 0.2100
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.0034
    Cell Significance Index: 0.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0017
    Cell Significance Index: 0.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0010
    Cell Significance Index: 0.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.8700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0007
    Cell Significance Index: -1.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0007
    Cell Significance Index: -0.0900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0018
    Cell Significance Index: -2.7500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0018
    Cell Significance Index: -2.4600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0035
    Cell Significance Index: -2.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0036
    Cell Significance Index: -0.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0041
    Cell Significance Index: -3.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0053
    Cell Significance Index: -3.0000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0057
    Cell Significance Index: -1.6300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0057
    Cell Significance Index: -3.5800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0059
    Cell Significance Index: -2.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0061
    Cell Significance Index: -2.7700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0076
    Cell Significance Index: -0.0500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0091
    Cell Significance Index: -1.3200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0097
    Cell Significance Index: -1.6500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0130
    Cell Significance Index: -2.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0131
    Cell Significance Index: -1.8000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0140
    Cell Significance Index: -0.2000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0160
    Cell Significance Index: -3.3700
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0184
    Cell Significance Index: -0.2200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0190
    Cell Significance Index: -2.2200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0191
    Cell Significance Index: -2.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0213
    Cell Significance Index: -2.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0235
    Cell Significance Index: -3.0400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0235
    Cell Significance Index: -1.2200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0235
    Cell Significance Index: -0.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0240
    Cell Significance Index: -1.1200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0253
    Cell Significance Index: -2.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0276
    Cell Significance Index: -2.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0334
    Cell Significance Index: -2.5600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0336
    Cell Significance Index: -1.4600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0378
    Cell Significance Index: -2.3800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0380
    Cell Significance Index: -0.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0395
    Cell Significance Index: -2.4300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0402
    Cell Significance Index: -3.0000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0420
    Cell Significance Index: -0.8800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0449
    Cell Significance Index: -1.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0461
    Cell Significance Index: -2.0900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0461
    Cell Significance Index: -3.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0462
    Cell Significance Index: -2.9800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0480
    Cell Significance Index: -2.5000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0480
    Cell Significance Index: -0.7700
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0483
    Cell Significance Index: -1.2300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0538
    Cell Significance Index: -1.0500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0563
    Cell Significance Index: -3.1600
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.0569
    Cell Significance Index: -0.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0634
    Cell Significance Index: -2.9800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0650
    Cell Significance Index: -1.1200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0662
    Cell Significance Index: -2.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0674
    Cell Significance Index: -2.9800
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.0691
    Cell Significance Index: -0.9400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0750
    Cell Significance Index: -2.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0755
    Cell Significance Index: -2.4100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0764
    Cell Significance Index: -2.5000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0791
    Cell Significance Index: -0.8600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0798
    Cell Significance Index: -3.0200
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.0801
    Cell Significance Index: -1.1400
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0808
    Cell Significance Index: -0.9500
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: -0.0811
    Cell Significance Index: -0.9800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0817
    Cell Significance Index: -2.1900
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.0837
    Cell Significance Index: -0.9500
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.0847
    Cell Significance Index: -1.1600
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.0899
    Cell Significance Index: -0.9400
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0908
    Cell Significance Index: -1.0700
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: -0.0930
    Cell Significance Index: -1.0400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0935
    Cell Significance Index: -2.7600
  • Cell Name: myoblast (CL0000056)
    Fold Change: -0.0957
    Cell Significance Index: -0.9400
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0975
    Cell Significance Index: -0.9400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0986
    Cell Significance Index: -2.4600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1009
    Cell Significance Index: -2.5200
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.1017
    Cell Significance Index: -1.1100
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.1044
    Cell Significance Index: -1.0800
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1045
    Cell Significance Index: -1.3400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1058
    Cell Significance Index: -1.7700
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1064
    Cell Significance Index: -1.4400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1071
    Cell Significance Index: -2.8600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1074
    Cell Significance Index: -2.3200
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.1076
    Cell Significance Index: -1.0300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1078
    Cell Significance Index: -3.0900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1094
    Cell Significance Index: -3.4600
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: -0.1103
    Cell Significance Index: -1.0800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1107
    Cell Significance Index: -2.3500
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1132
    Cell Significance Index: -1.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RHAG is a transmembrane glycoprotein that is specifically expressed in erythrocytes, as well as in other cell types such as colon goblet cells and intestinal crypt stem cells. The gene encodes for the RHAG_HUMAN protein, which is composed of multiple transmembrane domains and is involved in the transport of small molecules, including ammonium, carbon dioxide, and oxygen. RHAG is also a key component of the ankyrin-1 complex, which regulates the structural integrity of the erythrocyte membrane. **Pathways and Functions:** RHAG is a critical regulator of erythrocyte function, and its dysregulation can lead to various pathophysiological consequences. The main pathways and functions of RHAG include: 1. **Ammonium transport:** RHAG plays a crucial role in the transport of ammonium across the erythrocyte membrane, which is essential for maintaining ammonium homeostasis in the body. 2. **Carbon dioxide and oxygen exchange:** RHAG is involved in the exchange of carbon dioxide and oxygen between the erythrocyte and the bloodstream, which is critical for maintaining acid-base balance and oxygen delivery to tissues. 3. **Ion homeostasis:** RHAG helps regulate the transport of ions, including potassium, sodium, and chloride, across the erythrocyte membrane, which is essential for maintaining ion homeostasis and preventing electrolyte imbalances. 4. **Transmembrane transport:** RHAG is a transmembrane transporter that regulates the transport of small molecules, including ammonium, carbon dioxide, and oxygen, across the erythrocyte membrane. **Clinical Significance:** Mutations in the RHAG gene have been linked to defective rh-null hemolytic anemia (RHN), a severe disorder characterized by the premature destruction of erythrocytes. RHN is caused by the absence or dysfunction of RHAG, which leads to impaired ammonium transport and subsequent erythrocyte damage. Other disorders, such as disorders of transmembrane transporters and Slc-mediated transmembrane transport, have also been associated with RHAG dysfunction. Understanding the role of RHAG in erythrocyte function and transmembrane transport is essential for developing novel therapeutic strategies for patients with RHN and other related disorders. In conclusion, the RHAG gene plays a critical role in maintaining the integrity and function of erythrocytes, and its dysregulation can lead to various pathophysiological consequences. Further research on the RHAG gene and its associated disorders is essential for developing novel therapeutic strategies and improving patient outcomes.

Genular Protein ID: 927033646

Symbol: RHAG_HUMAN

Name: Erythrocyte membrane glycoprotein Rh50

UniProtKB Accession Codes:

Q02094 B2R8T8 O43514 O43515 Q7L8L3 Q9H454

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 3 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 EMDB 8 Ensembl 2 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1417776

Title: Isolation of cDNA clones for a 50 kDa glycoprotein of the human erythrocyte membrane associated with Rh (rhesus) blood-group antigen expression.

PubMed ID: 1417776

DOI: 10.1042/bj2870223

PubMed ID: 9442063

Title: The human Rh50 glycoprotein gene. Structural organization and associated splicing defect resulting in Rh(null) disease.

PubMed ID: 9442063

DOI: 10.1074/jbc.273.4.2207

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 9473510

Title: Identification of 5' flanking sequence of RH50 gene and the core region for erythroid-specific expression.

PubMed ID: 9473510

DOI: 10.1006/bbrc.1997.8023

PubMed ID: 3146980

Title: Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.

PubMed ID: 3146980

DOI: 10.1042/bj2561043

PubMed ID: 11062476

Title: The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast.

PubMed ID: 11062476

DOI: 10.1038/81656

PubMed ID: 11861637

Title: Identification of the erythrocyte Rh blood group glycoprotein as a mammalian ammonium transporter.

PubMed ID: 11861637

DOI: 10.1074/jbc.c200060200

PubMed ID: 12130520

Title: Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein.

PubMed ID: 12130520

PubMed ID: 14966114

Title: Mechanism of genetic complementation of ammonium transport in yeast by human erythrocyte Rh-associated glycoprotein.

PubMed ID: 14966114

DOI: 10.1074/jbc.m311853200

PubMed ID: 15572441

Title: Human Rhesus-associated glycoprotein mediates facilitated transport of NH(3) into red blood cells.

PubMed ID: 15572441

DOI: 10.1073/pnas.0403704101

PubMed ID: 15856280

Title: Expression of the human erythroid Rh glycoprotein (RhAG) enhances both NH3 and NH4+ transport in HeLa cells.

PubMed ID: 15856280

DOI: 10.1007/s00424-005-1381-y

PubMed ID: 17712059

Title: RhAG protein of the Rhesus complex is a CO2 channel in the human red cell membrane.

PubMed ID: 17712059

DOI: 10.1096/fj.07-9097com

PubMed ID: 19273840

Title: Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG.

PubMed ID: 19273840

DOI: 10.1073/pnas.0813231106

PubMed ID: 24077989

Title: Relative CO(2)/NH(3) permeabilities of human RhAG, RhBG and RhCG.

PubMed ID: 24077989

DOI: 10.1007/s00232-013-9593-0

PubMed ID: 27247322

Title: Severe Ankyrin-R deficiency results in impaired surface retention and lysosomal degradation of RhAG in human erythroblasts.

PubMed ID: 27247322

DOI: 10.3324/haematol.2016.146209

PubMed ID: 26354748

Title: Mechanisms of ammonia and ammonium transport by rhesus-associated glycoproteins.

PubMed ID: 26354748

DOI: 10.1152/ajpcell.00085.2015

PubMed ID: 35835865

Title: Architecture of the human erythrocyte ankyrin-1 complex.

PubMed ID: 35835865

DOI: 10.1038/s41594-022-00792-w

PubMed ID: 8563755

Title: Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency.

PubMed ID: 8563755

DOI: 10.1038/ng0296-168

PubMed ID: 9454778

Title: A novel single missense mutation identified along the RH50 gene in a composite heterozygous Rhnull blood donor of the regulator type.

PubMed ID: 9454778

PubMed ID: 9716608

Title: Rh50 glycoprotein gene and rhnull disease: a silent splice donor is trans to a Gly279-->Glu missense mutation in the conserved transmembrane segment.

PubMed ID: 9716608

PubMed ID: 10467273

Title: Molecular basis for Rh(null) syndrome: identification of three new missense mutations in the Rh50 glycoprotein gene.

PubMed ID: 10467273

DOI: 10.1002/(sici)1096-8652(199909)62:1<25::aid-ajh5>3.0.co;2-k

PubMed ID: 18931342

Title: The monovalent cation leak in overhydrated stomatocytic red blood cells results from amino acid substitutions in the Rh-associated glycoprotein.

PubMed ID: 18931342

DOI: 10.1182/blood-2008-07-171140

PubMed ID: 19744193

Title: A new blood group system, RHAG: three antigens resulting from amino acid substitutions in the Rh-associated glycoprotein.

PubMed ID: 19744193

DOI: 10.1111/j.1423-0410.2009.01243.x

PubMed ID: 21849667

Title: Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S.

PubMed ID: 21849667

DOI: 10.1152/ajpcell.00054.2011

PubMed ID: 22012326

Title: Human RhAG ammonia channel is impaired by the Phe65Ser mutation in overhydrated stomatocytic red cells.

PubMed ID: 22012326

DOI: 10.1152/ajpcell.00092.2011

PubMed ID: 27535533

Title: Analysis of protein-coding genetic variation in 60,706 humans.

PubMed ID: 27535533

DOI: 10.1038/nature19057

Sequence Information:

  • Length: 409
  • Mass: 44198
  • Checksum: F6F024399CC0C88D
  • Sequence:
    • MRFTFPLMAI VLEIAMIVLF GLFVEYETDQ TVLEQLNITK PTDMGIFFEL YPLFQDVHVM 
IFVGFGFLMT FLKKYGFSSV GINLLVAALG LQWGTIVQGI LQSQGQKFNI GIKNMINADF 
SAATVLISFG AVLGKTSPTQ MLIMTILEIV FFAHNEYLVS EIFKASDIGA SMTIHAFGAY 
FGLAVAGILY RSGLRKGHEN EESAYYSDLF AMIGTLFLWM FWPSFNSAIA EPGDKQCRAI 
VNTYFSLAAC VLTAFAFSSL VEHRGKLNMV HIQNATLAGG VAVGTCADMA IHPFGSMIIG 
SIAGMVSVLG YKFLTPLFTT KLRIHDTCGV HNLHGLPGVV GGLAGIVAVA MGASNTSMAM 
QAAALGSSIG TAVVGGLMTG LILKLPLWGQ PSDQNCYDDS VYWKVPKTR

Genular Protein ID: 2651277863

Symbol: Q96E98_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96E98

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 3 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 Rhea 3 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 409
  • Mass: 44205
  • Checksum: 0F62B06341325FD6
  • Sequence:
    • MRFTFPLMAI VLEIAMIVLF GLFVEYETDQ TVLEQLNITK PTDMGIFFEL YPLFQDVHVM 
IFVGFGFLMT FLKKYGFSSV GINLLVAALG LQWGTIVQGT LQSQGQKFNI GIKNMINADF 
SAATVLISFG AVLGKTSPTQ MLIMTILEIV FFAHNEYLVS EIFKASDIGA SMTIHAFGAY 
FGLAVAGILY RSGLRKGREN EESAYYSDLF AMIGTLFLWM FWPSFNSAIA EPGDKQCRAI 
VNTYFSLAAC VLTAFAFSSL VEHRGKLNMV HIQNATLAGG VAVGTCADMA IHPFGSMIIG 
SIAGMVSVLG YKFLTPLFTT KLRIHDTCGV HNLHGLPGVV GGLAGIVAVA MGASNTSMAM 
QAAALGSSIG TAVVGGLMTG LILKLPLWGQ PSDQNCYDDS VYWKVPKTR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.