Details for: PTGS1

Gene ID: 5742

Symbol: PTGS1

Ensembl ID: ENSG00000095303

Description: prostaglandin-endoperoxide synthase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 56.0609
    Cell Significance Index: -8.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 34.6944
    Cell Significance Index: -8.8000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 19.6771
    Cell Significance Index: -9.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.5443
    Cell Significance Index: -7.9400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 18.4589
    Cell Significance Index: -9.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.6807
    Cell Significance Index: -9.4700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.7311
    Cell Significance Index: -10.0000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 3.7143
    Cell Significance Index: 37.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 3.5925
    Cell Significance Index: 683.6800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.2578
    Cell Significance Index: -7.1300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 2.4696
    Cell Significance Index: 244.3000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.4582
    Cell Significance Index: -9.7000
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.4108
    Cell Significance Index: 11.7300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2919
    Cell Significance Index: 210.1200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2004
    Cell Significance Index: 130.5700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.1462
    Cell Significance Index: 26.4800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7350
    Cell Significance Index: 50.8300
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.7039
    Cell Significance Index: 5.0600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5920
    Cell Significance Index: 35.5400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.3415
    Cell Significance Index: 7.3000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2025
    Cell Significance Index: 5.6600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1874
    Cell Significance Index: 2.9000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1079
    Cell Significance Index: 0.8800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0694
    Cell Significance Index: 37.8800
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.0631
    Cell Significance Index: 0.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0481
    Cell Significance Index: 21.2800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0463
    Cell Significance Index: 2.9900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0253
    Cell Significance Index: 17.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0160
    Cell Significance Index: 0.4000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0073
    Cell Significance Index: 0.7500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0062
    Cell Significance Index: 0.1800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0059
    Cell Significance Index: 0.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0055
    Cell Significance Index: 0.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0028
    Cell Significance Index: 0.1000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0037
    Cell Significance Index: -2.3100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0045
    Cell Significance Index: -8.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0049
    Cell Significance Index: -3.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0067
    Cell Significance Index: -0.9200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0071
    Cell Significance Index: -13.1000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0084
    Cell Significance Index: -12.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0092
    Cell Significance Index: -1.0900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0096
    Cell Significance Index: -5.3900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0097
    Cell Significance Index: -13.1900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0108
    Cell Significance Index: -0.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0117
    Cell Significance Index: -8.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0136
    Cell Significance Index: -8.6400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0165
    Cell Significance Index: -3.3100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0189
    Cell Significance Index: -3.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0204
    Cell Significance Index: -4.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0207
    Cell Significance Index: -0.4400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0212
    Cell Significance Index: -9.6100
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0216
    Cell Significance Index: -0.1800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0227
    Cell Significance Index: -6.5200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0241
    Cell Significance Index: -8.6300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0254
    Cell Significance Index: -0.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0297
    Cell Significance Index: -5.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0395
    Cell Significance Index: -7.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0509
    Cell Significance Index: -2.5700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0530
    Cell Significance Index: -6.0500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0570
    Cell Significance Index: -8.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0595
    Cell Significance Index: -7.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0664
    Cell Significance Index: -7.7400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0690
    Cell Significance Index: -8.9100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0772
    Cell Significance Index: -9.9000
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0798
    Cell Significance Index: -0.6900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0890
    Cell Significance Index: -9.2700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0977
    Cell Significance Index: -11.1900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1102
    Cell Significance Index: -3.5300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1157
    Cell Significance Index: -8.8800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1164
    Cell Significance Index: -3.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1197
    Cell Significance Index: -8.9200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1264
    Cell Significance Index: -3.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1272
    Cell Significance Index: -5.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1305
    Cell Significance Index: -8.0000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1460
    Cell Significance Index: -9.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1480
    Cell Significance Index: -7.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1520
    Cell Significance Index: -9.5800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1531
    Cell Significance Index: -7.1400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1606
    Cell Significance Index: -6.5800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1708
    Cell Significance Index: -10.5000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1845
    Cell Significance Index: -2.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1869
    Cell Significance Index: -10.4900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1873
    Cell Significance Index: -4.6700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1902
    Cell Significance Index: -2.7300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1904
    Cell Significance Index: -9.8900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1920
    Cell Significance Index: -7.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1974
    Cell Significance Index: -8.7300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2067
    Cell Significance Index: -2.9600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2075
    Cell Significance Index: -5.9200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2194
    Cell Significance Index: -5.4800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2308
    Cell Significance Index: -8.7400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2498
    Cell Significance Index: -8.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2642
    Cell Significance Index: -9.1800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2715
    Cell Significance Index: -8.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2829
    Cell Significance Index: -7.7000
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.2861
    Cell Significance Index: -3.9700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2873
    Cell Significance Index: -9.1500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2974
    Cell Significance Index: -7.9700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2988
    Cell Significance Index: -8.8000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3043
    Cell Significance Index: -5.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** PTGS1 is widely expressed in various cell types, including basophils, colon goblet cells, dendritic cells, and neurons. 2. **Enzymatic Activity:** PTGS1 is a non-heme iron-dependent dioxygenase that catalyzes the conversion of arachidonic acid into PGH2. 3. **Subcellular Localization:** PTGS1 is primarily localized to the endoplasmic reticulum membrane and the cytoplasm. 4. **Regulatory Mechanisms:** PTGS1 is subject to various regulatory mechanisms, including transcriptional control by prostaglandin receptors and post-transcriptional regulation by microRNAs. **Pathways and Functions:** 1. **Arachidonic Acid Metabolism:** PTGS1 is a key enzyme in the arachidonic acid metabolism pathway, which is involved in the production of eicosanoids, including prostaglandins, thromboxanes, and leukotrienes. 2. **Cyclooxygenase Pathway:** PTGS1 is a member of the cyclooxygenase (COX) family, which is responsible for the production of prostaglandins and thromboxanes. 3. **Regulation of Blood Pressure:** PTGS1 is involved in the regulation of blood pressure through the production of prostaglandins, which modulate vascular tone and blood pressure. 4. **Inflammation and Immune Response:** PTGS1 is also involved in the regulation of inflammation and immune response through the production of eicosanoids, which interact with immune cells and modulate their activity. **Clinical Significance:** 1. **Cancer:** Overexpression of PTGS1 has been observed in various types of cancer, including colorectal, breast, and lung cancer, suggesting its potential role as a tumor suppressor gene. 2. **Inflammatory Diseases:** PTGS1 has been implicated in the pathogenesis of various inflammatory diseases, including arthritis, asthma, and cardiovascular disease. 3. **Neurological Disorders:** PTGS1 has been linked to neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 4. **Therapeutic Applications:** Inhibitors of PTGS1, such as non-steroidal anti-inflammatory drugs (NSAIDs), have been used to treat various inflammatory and pain-related disorders. In conclusion, PTGS1 is a critical enzyme involved in the regulation of various physiological and pathological processes. Its dysregulation has been implicated in various diseases, including cancer, inflammatory diseases, and neurological disorders. Further research is needed to fully elucidate the role of PTGS1 in human health and disease.

Genular Protein ID: 1113416111

Symbol: PGH1_HUMAN

Name: Prostaglandin H2 synthase 1

UniProtKB Accession Codes:

P23219 A8K1V7 B4DHQ2 B4E2S5 Q15122 Q3HY28 Q3HY29 Q5T7T6 Q5T7T7 Q5T7T8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEBI 41 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 100 DrugCentral 1 EC 1 EMBL 26 Ensembl 4 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PeroxiBase 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 Rhea 14 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2512924

Title: Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme.

PubMed ID: 2512924

DOI: 10.1016/s0006-291x(89)80049-x

PubMed ID: 1907252

Title: Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment.

PubMed ID: 1907252

DOI: 10.1096/fasebj.5.9.1907252

PubMed ID: 1734857

Title: Immunoaffinity purification and cDNA cloning of human platelet prostaglandin endoperoxide synthase (cyclooxygenase).

PubMed ID: 1734857

DOI: 10.1016/0006-291x(92)91750-k

PubMed ID: 1587858

Title: Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha.

PubMed ID: 1587858

DOI: 10.1016/s0021-9258(19)50092-8

PubMed ID: 16141368

Title: Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention.

PubMed ID: 16141368

DOI: 10.1124/jpet.105.090944

PubMed ID: 12192304

Title: Characterization of the human prostaglandin H synthase 1 gene (PTGS1): exclusion by genetic linkage analysis as a second modifier gene in familial thrombosis.

PubMed ID: 12192304

DOI: 10.1097/00001721-200209000-00007

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7947975

Title: Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system.

PubMed ID: 7947975

DOI: 10.1016/0167-4838(94)90148-1

PubMed ID: 10966456

Title: Cyclooxygenases: structural, cellular, and molecular biology.

PubMed ID: 10966456

DOI: 10.1146/annurev.biochem.69.1.145

PubMed ID: 24605250

Title: Aspirin, cyclooxygenase inhibition and colorectal cancer.

PubMed ID: 24605250

DOI: 10.4292/wjgpt.v5.i1.40

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 15308583

Title: Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk.

PubMed ID: 15308583

DOI: 10.1093/carcin/bgh260

Sequence Information:

  • Length: 599
  • Mass: 68686
  • Checksum: 1F4F734BCD00346D
  • Sequence:
    • MSRSLLLWFL LFLLLLPPLP VLLADPGAPT PVNPCCYYPC QHQGICVRFG LDRYQCDCTR 
TGYSGPNCTI PGLWTWLRNS LRPSPSFTHF LLTHGRWFWE FVNATFIREM LMRLVLTVRS 
NLIPSPPTYN SAHDYISWES FSNVSYYTRI LPSVPKDCPT PMGTKGKKQL PDAQLLARRF 
LLRRKFIPDP QGTNLMFAFF AQHFTHQFFK TSGKMGPGFT KALGHGVDLG HIYGDNLERQ 
YQLRLFKDGK LKYQVLDGEM YPPSVEEAPV LMHYPRGIPP QSQMAVGQEV FGLLPGLMLY 
ATLWLREHNR VCDLLKAEHP TWGDEQLFQT TRLILIGETI KIVIEEYVQQ LSGYFLQLKF 
DPELLFGVQF QYRNRIAMEF NHLYHWHPLM PDSFKVGSQE YSYEQFLFNT SMLVDYGVEA 
LVDAFSRQIA GRIGGGRNMD HHILHVAVDV IRESREMRLQ PFNEYRKRFG MKPYTSFQEL 
VGEKEMAAEL EELYGDIDAL EFYPGLLLEK CHPNSIFGES MIEIGAPFSL KGLLGNPICS 
PEYWKPSTFG GEVGFNIVKT ATLKKLVCLN TKTCPYVSFR VPDASQDDGP AVERPSTEL

Genular Protein ID: 2629423425

Symbol: A0A087X296_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X296

Database IDs:

ARBA 32 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 41 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 10 Gene3D 2 GeneTree 1 GlyCosmos 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 14 SAM 1 SMR 1 SUPFAM 2 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 551
  • Mass: 63286
  • Checksum: 8FB64B70ECFB4662
  • Sequence:
    • MSRSLLLWFL LFLLLLPPLP VLLADPGAPT PVNPCCYYPC QHQGICVRFG LDRYQCDCTR 
TGYSGPNCTI PGLWTWLRNS LRPSPSFTHF LLTHGRWFWE FVNATFIREM LMRLVLTGKK 
QLPDAQLLAR RFLLRRKFIP DPQGTNLMFA FFAQHFTHQF FKTSGKMGPG FTKALGHGVD 
LGHIYGDNLE RQYQLRLFKD GKLKYQVLDG EMYPPSVEEA PVLMHYPRGI PPQSQMAVGQ 
EVFGLLPGLM LYATLWLREH NRVCDLLKAE HPTWGDEQLF QTTRLILIGE TIKIVIEEYV 
QQLSGYFLQL KFDPELLFGV QFQYRNRIAM EFNHLYHWHP LMPDSFKVGS QEYSYEQFLF 
NTSMLVDYGV EALVDAFSRQ IAGRIGGGRN MDHHILHVAV DVIRESREMR LQPFNEYRKR 
FGMKPYTSFQ ELVGEKEMAA ELEELYGDID ALEFYPGLLL EKCHPNSIFG ESMIEIGAPF 
SLKGLLGNPI CSPEYWKPST FGGEVGFNIV KTATLKKLVC LNTKTCPYVS FRVPDASQDD 
GPAVERPSTE L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.