Details for: SH2B2

Gene ID: 10603

Symbol: SH2B2

Ensembl ID: ENSG00000160999

Description: SH2B adaptor protein 2

Associated with

Other Information

Genular Protein ID: 2435315940

Symbol: SH2B2_HUMAN

Name: SH2B adapter protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9233773

Title: Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation.

PubMed ID: 9233773

DOI: 10.1038/sj.onc.1201163

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 10374881

Title: APS, an adaptor protein containing pleckstrin homology (PH) and Src homology-2 (SH2) domains inhibits the JAK-STAT pathway in collaboration with c-Cbl.

PubMed ID: 10374881

DOI: 10.1038/sj.leu.2401397

PubMed ID: 9989826

Title: APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.

PubMed ID: 9989826

DOI: 10.1038/sj.onc.1202326

PubMed ID: 12400014

Title: Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity.

PubMed ID: 12400014

DOI: 10.1038/sj.onc.1205927

PubMed ID: 16129412

Title: Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor.

PubMed ID: 16129412

DOI: 10.1016/j.bbrc.2005.08.055

PubMed ID: 15378031

Title: A phenylalanine zipper mediates APS dimerization.

PubMed ID: 15378031

DOI: 10.1038/nsmb829

Sequence Information:

  • Length: 632
  • Mass: 67738
  • Checksum: 823DF1699D404227
  • Sequence:
  • MNGAGPGPAA AAPVPVPVPV PDWRQFCELH AQAAAVDFAH KFCRFLRDNP AYDTPDAGAS 
    FSRHFAANFL DVFGEEVRRV LVAGPTTRGA AVSAEAMEPE LADTSALKAA PYGHSRSSED 
    VSTHAATKAR VRKGFSLRNM SLCVVDGVRD MWHRRASPEP DAAAAPRTAE PRDKWTRRLR 
    LSRTLAAKVE LVDIQREGAL RFMVADDAAA GSGGSAQWQK CRLLLRRAVA EERFRLEFFV 
    PPKASRPKVS IPLSAIIEVR TTMPLEMPEK DNTFVLKVEN GAEYILETID SLQKHSWVAD 
    IQGCVDPGDS EEDTELSCTR GGCLASRVAS CSCELLTDAV DLPRPPETTA VGAVVTAPHS 
    RGRDAVRESL IHVPLETFLQ TLESPGGSGS DSNNTGEQGA ETDPEAEPEL ELSDYPWFHG 
    TLSRVKAAQL VLAGGPRNHG LFVIRQSETR PGEYVLTFNF QGKAKHLRLS LNGHGQCHVQ 
    HLWFQSVLDM LRHFHTHPIP LESGGSADIT LRSYVRAQDP PPEPGPTPPA APASPACWSD 
    SPGQHYFSSL AAAACPPASP SDAAGASSSS ASSSSAASGP APPRPVEGQL SARSRSNSAE 
    RLLEAVAATA AEEPPEAAPG RARAVENQYS FY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.