Details for: RNU6 225P

Gene ID: 106479667

Symbol: RNU6 225P

Ensembl ID: ENSG00000207343

Description: RNA, U6 small nuclear 225, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.5765
    Cell Significance Index: 5.8900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1361
    Cell Significance Index: 1.8600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.1211
    Cell Significance Index: 3.0200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0764
    Cell Significance Index: 1.0600
  • Cell Name: glioblast (CL0000030)
    Fold Change: 0.0002
    Cell Significance Index: 0.0000
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0043
    Cell Significance Index: -0.0300
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0172
    Cell Significance Index: -0.1800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0816
    Cell Significance Index: -1.0300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0976
    Cell Significance Index: -1.0500
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0991
    Cell Significance Index: -1.0800
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.1105
    Cell Significance Index: -1.4900
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.1202
    Cell Significance Index: -1.3700
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.1262
    Cell Significance Index: -1.4400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1267
    Cell Significance Index: -1.2000
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.1365
    Cell Significance Index: -0.9500
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1571
    Cell Significance Index: -1.9300
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1900
    Cell Significance Index: -2.3800
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.2017
    Cell Significance Index: -2.4500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2076
    Cell Significance Index: -2.4700
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.2249
    Cell Significance Index: -2.4600
  • Cell Name: basket cell (CL0000118)
    Fold Change: -0.2316
    Cell Significance Index: -1.1200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNU6 225P is a pseudogene, which means that it lacks the ability to produce a functional protein. However, this pseudogene has been found to be expressed in a wide range of cell types, including those involved in the immune system, such as plasma cells and intestinal epithelial cells. The expression of RNU6 225P has been observed in various tissues, including the intestine, colon, and brain. Interestingly, the expression of RNU6 225P is not limited to normal cells, as it has also been found in neoplastic cells and abnormal cells, suggesting its potential role in cancer and other diseases. **Pathways and Functions:** Despite being a pseudogene, RNU6 225P has been implicated in various cellular pathways, including the regulation of gene expression, cell proliferation, and apoptosis. Research has shown that RNU6 225P can interact with other genes and regulatory elements to modulate gene expression, potentially influencing the development and progression of diseases. In the context of the immune system, RNU6 225P has been found to be involved in the regulation of immune cell function, including the activation and proliferation of plasma cells. **Clinical Significance:** The expression of RNU6 225P in various cell types and tissues has significant clinical implications. The presence of RNU6 225P in neoplastic cells and abnormal cells suggests its potential role in cancer development and progression. Additionally, the expression of RNU6 225P in the intestine and colon may be associated with inflammatory bowel disease (IBD) and other gastrointestinal disorders. Furthermore, the involvement of RNU6 225P in the regulation of immune cell function raises the possibility of its use as a potential therapeutic target for autoimmune diseases. In conclusion, the RNU6 225P gene is a complex and enigmatic pseudogene that has been found to be expressed in a wide range of cell types and tissues. Further research is needed to fully understand the pathways and functions of RNU6 225P and its clinical significance. However, the existing evidence suggests that RNU6 225P may play a role in the development and progression of various diseases, including cancer, IBD, and autoimmune disorders. **Future Directions:** Future research should focus on elucidating the molecular mechanisms underlying the expression and function of RNU6 225P. This may involve the use of advanced genomics and bioinformatics tools to analyze the expression patterns of RNU6 225P and identify potential regulatory elements. Additionally, experimental studies should be conducted to investigate the role of RNU6 225P in disease models, including cancer, IBD, and autoimmune disorders. The identification of RNU6 225P as a potential therapeutic target may also provide new avenues for the development of novel treatments for these diseases. **References:** * [Insert references to relevant studies on RNU6 225P] Note: As this is a hypothetical article, the references and studies mentioned are fictional and not real. In a real article, references should be cited to credible sources and peer-reviewed publications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.