SLC35C1 | ENSG00000181830 | NCBI 55343

Details for: SLC35C1

Gene ID: 55343

Symbol: SLC35C1

Ensembl ID: ENSG00000181830

Description: solute carrier family 35 member C1

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-HSA-446193)
Defective slc35c1 causes congenital disorder of glycosylation 2c (cdg2c)
(R-HSA-5619078)
Disease
(R-HSA-1643685)
Disorders of transmembrane transporters
(R-HSA-5619115)
Gdp-fucose biosynthesis
(R-HSA-6787639)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Slc-mediated transmembrane transport
(R-HSA-425407)
Slc transporter disorders
(R-HSA-5619102)
Synthesis of substrates in n-glycan biosythesis
(R-HSA-446219)
Transport of nucleotide sugars
(R-HSA-727802)
Transport of small molecules
(R-HSA-382551)
Transport of vitamins, nucleosides, and related molecules
(R-HSA-425397)
Antiporter activity
(GO:0015297)
Carbohydrate transport
(GO:0008643)
Gdp-fucose import into golgi lumen
(GO:0036085)
Gdp-fucose transmembrane transporter activity
(GO:0005457)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Lipid glycosylation
(GO:0030259)
Negative regulation of notch signaling pathway
(GO:0045746)
Protein o-linked fucosylation
(GO:0036066)

Other Information

Proteins

Solute carrier family 35 member C1

Genular Protein ID: 423961113

Symbol: FUCT1_HUMAN

Name: Solute carrier family 35 member C1

UniProtKB Accession Codes:

Q96A29 B2RDB2 Q9BV76 Q9NUJ8

Database IDs:

Citations:

PubMed ID: 11326279

Title: The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter.

PubMed ID: 11326279

DOI: 10.1038/ng0501-69

PubMed ID: 11326280

Title: Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency.

PubMed ID: 11326280

DOI: 10.1038/ng0501-73

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 27738779

Title: Functional expression of a human GDP-L-fucose transporter in Escherichia coli.

PubMed ID: 27738779

DOI: 10.1007/s10529-016-2233-x

Sequence Information:

Length: 364
Mass: 39809
Checksum: 2E659D49C5C5E92E
Sequence:

MNRAPLKRSR ILHMALTGAS DPSAEAEANG EKPFLLRALQ IALVVSLYWV TSISMVFLNK 
YLLDSPSLRL DTPIFVTFYQ CLVTTLLCKG LSALAACCPG AVDFPSLRLD LRVARSVLPL 
SVVFIGMITF NNLCLKYVGV AFYNVGRSLT TVFNVLLSYL LLKQTTSFYA LLTCGIIIGG 
FWLGVDQEGA EGTLSWLGTV FGVLASLCVS LNAIYTTKVL PAVDGSIWRL TFYNNVNACI 
LFLPLLLLLG ELQALRDFAQ LGSAHFWGMM TLGGLFGFAI GYVTGLQIKF TSPLTHNVSG 
TAKACAQTVL AVLYYEETKS FLWWTSNMMV LGGSSAYTWV RGWEMKKTPE EPSPKDSEKS 
AMGV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC35C1

Associated with

Other Information

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. PubMed ID: 11326279

Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. PubMed ID: 11326280

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334