Details for: IGLV11 55

Gene ID: 28770

Symbol: IGLV11 55

Ensembl ID: ENSG00000211641

Description: immunoglobulin lambda variable 11-55 (non-functional)

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: T cell (CL0000084)
    Fold Change: 2.54
    Marker Score: 4,377
  • Cell Name: B cell (CL0000236)
    Fold Change: 1.06
    Marker Score: 1,010
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.86
    Marker Score: 500
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.74
    Marker Score: 1,194
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.72
    Marker Score: 699
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.44
    Marker Score: 495
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.43
    Marker Score: 387
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.16
    Marker Score: 108
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 0.07
    Marker Score: 25
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: 0.05
    Marker Score: 23
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.05
    Marker Score: 66
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 0.04
    Marker Score: 27
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.04
    Marker Score: 27
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 0.03
    Marker Score: 29
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.03
    Marker Score: 27
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.03
    Marker Score: 27
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.02
    Marker Score: 70
  • Cell Name: B-2 B cell (CL0000822)
    Fold Change: 0.02
    Marker Score: 27
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.02
    Marker Score: 24
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 0.02
    Marker Score: 22
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.02
    Marker Score: 49
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.02
    Marker Score: 25
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.01
    Marker Score: 27
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.01
    Marker Score: 29
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0
    Marker Score: 25
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0
    Marker Score: 27

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IGLV11 55 is a lambda variable gene, which is a type of immunoglobulin gene that codes for the variable region of the immunoglobulin molecule. The lambda variable region is responsible for recognizing and binding to specific antigens. IGLV11 55 is classified as a non-functional gene, meaning that it does not produce a functional immunoglobulin molecule. Despite this, the gene is still expressed in various cell types, suggesting that it may play a role in regulating gene expression, cell signaling, or other cellular processes. **Pathways and Functions** The pathways and functions of IGLV11 55 are not well understood, but it is likely that this gene plays a role in regulating the expression of other genes involved in the immune response. Some possible functions of IGLV11 55 include: 1. **Regulation of B cell development**: IGLV11 55 may play a role in regulating the development and maturation of B cells, which are the primary producers of antibodies. 2. **Cell signaling**: IGLV11 55 may be involved in cell signaling pathways that regulate the immune response, such as the activation of T cells or the production of cytokines. 3. **Gene expression regulation**: IGLV11 55 may regulate the expression of other genes involved in the immune response, such as genes involved in antigen presentation or immune cell activation. 4. **Cell adhesion**: IGLV11 55 may be involved in cell adhesion processes, such as the adhesion of immune cells to endothelial cells or the adhesion of immune cells to other cells. **Clinical Significance** The clinical significance of IGLV11 55 is not well understood, but it is possible that this gene plays a role in the development of immune-related diseases. Some potential clinical applications of IGLV11 55 include: 1. **Immunotherapy**: IGLV11 55 may be used as a target for immunotherapies aimed at modulating the immune response in diseases such as cancer or autoimmune disorders. 2. **Immunodeficiency**: IGLV11 55 may be used to develop novel therapies for immunodeficiency diseases, such as X-linked agammaglobulinemia (XLA) or common variable immunodeficiency (CVID). 3. **Cancer research**: IGLV11 55 may be used as a biomarker for cancer research, as it is widely expressed across various cell types and may be involved in the development of cancer. In conclusion, IGLV11 55 is a non-functional gene that is widely expressed across various cell types. While its functions are not well understood, it is possible that this gene plays a role in regulating gene expression, cell signaling, or other cellular processes. Further research is needed to fully understand the significance of IGLV11 55 and its potential clinical applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.