ITLN1 | ENSG00000179914 | NCBI 55600

Details for: ITLN1

Gene ID: 55600

Symbol: ITLN1

Ensembl ID: ENSG00000179914

Description: intelectin 1

Associated with

Antimicrobial peptides
(R-HSA-6803157)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Brush border membrane
(GO:0031526)
Calcium ion binding
(GO:0005509)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Membrane raft
(GO:0045121)
Oligosaccharide binding
(GO:0070492)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Protein homotrimerization
(GO:0070207)
Receptor complex
(GO:0043235)
Response to nematode
(GO:0009624)
Side of membrane
(GO:0098552)

Other Information

Proteins

Intelectin-1

Genular Protein ID: 2151465420

Symbol: ITLN1_HUMAN

Name: Intelectin-1

UniProtKB Accession Codes:

Q8WWA0 Q5IWS4 Q5VYI4 Q6YDJ3 Q9NP67

Database IDs:

Citations:

PubMed ID: 11747454

Title: Molecular cloning and functional expression of a human intestinal lactoferrin receptor.

PubMed ID: 11747454

DOI: 10.1021/bi0155899

PubMed ID: 11181563

Title: Human homologs of the Xenopus oocyte cortical granule lectin XL35.

PubMed ID: 11181563

DOI: 10.1093/glycob/11.1.65

PubMed ID: 11313366

Title: Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall.

PubMed ID: 11313366

DOI: 10.1074/jbc.m103162200

PubMed ID: 14720597

Title: The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins.

PubMed ID: 14720597

DOI: 10.1016/s1095-6433(03)00269-1

PubMed ID: 16531507

Title: Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action.

PubMed ID: 16531507

DOI: 10.1152/ajpendo.00572.2004

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17621593

Title: Differential structure and activity between human and mouse intelectin-1: human intelectin-1 is a disulfide-linked trimer, whereas mouse homologue is a monomer.

PubMed ID: 17621593

DOI: 10.1093/glycob/cwm075

PubMed ID: 23921499

Title: A lactoferrin-receptor, intelectin 1, affects uptake, sub-cellular localization and release of immunochemically detectable lactoferrin by intestinal epithelial Caco-2 cells.

PubMed ID: 23921499

DOI: 10.1093/jb/mvt073

PubMed ID: 26148048

Title: Recognition of microbial glycans by human intelectin-1.

PubMed ID: 26148048

DOI: 10.1038/nsmb.3053

Sequence Information:

Length: 313
Mass: 34962
Checksum: 56219FE937FC802E
Sequence:

MNQLSFLLFL IATTRGWSTD EANTYFKEWT CSSSPSLPRS CKEIKDECPS AFDGLYFLRT 
ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSQQGSKAVY PEGDGNWANY 
NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG 
HNLFGIYQKY PVKYGEGKCW TDNGPVIPVV YDFGDAQKTA SYYSPYGQRE FTAGFVQFRV 
FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPQQC GDFSGFDWSG YGTHVGYSSS 
REITEAAVLL FYR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ITLN1

Associated with

Other Information

Molecular cloning and functional expression of a human intestinal lactoferrin receptor. PubMed ID: 11747454

Human homologs of the Xenopus oocyte cortical granule lectin XL35. PubMed ID: 11181563

Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall. PubMed ID: 11313366

The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins. PubMed ID: 14720597

Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. PubMed ID: 16531507

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Differential structure and activity between human and mouse intelectin-1: human intelectin-1 is a disulfide-linked trimer, whereas mouse homologue is a monomer. PubMed ID: 17621593

A lactoferrin-receptor, intelectin 1, affects uptake, sub-cellular localization and release of immunochemically detectable lactoferrin by intestinal epithelial Caco-2 cells. PubMed ID: 23921499

Recognition of microbial glycans by human intelectin-1. PubMed ID: 26148048