Details for: RN7SL214P

Gene ID: 106479300

Symbol: RN7SL214P

Ensembl ID: ENSG00000242066

Description: RNA, 7SL, cytoplasmic 214, pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.0995
    Cell Significance Index: 1.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0884
    Cell Significance Index: 1.2100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0120
    Cell Significance Index: -0.6200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0245
    Cell Significance Index: -1.1100
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0562
    Cell Significance Index: -0.5900
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0598
    Cell Significance Index: -0.6700
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0782
    Cell Significance Index: -1.0300
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: -0.0800
    Cell Significance Index: -0.8500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0804
    Cell Significance Index: -1.3600
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0841
    Cell Significance Index: -0.7900
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1093
    Cell Significance Index: -1.2900
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.1277
    Cell Significance Index: -1.0800
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1287
    Cell Significance Index: -1.5800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1295
    Cell Significance Index: -1.5400
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.1309
    Cell Significance Index: -1.2700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.1335
    Cell Significance Index: -1.5800
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.1361
    Cell Significance Index: -1.3400
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1425
    Cell Significance Index: -1.4600
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.1698
    Cell Significance Index: -1.3400
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.1807
    Cell Significance Index: -0.9700
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: -0.4233
    Cell Significance Index: -1.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RN7SL214P is a pseudogene, meaning it lacks the coding potential for a protein. Its expression is significantly elevated in cells of the intestinal epithelium, including enteroendocrine cells, goblet cells, and absorptive cells. Additionally, RN7SL214P is expressed in fibroblasts, brush cells, and neurons, highlighting its non-specific expression pattern. Notably, RN7SL214P is also found in neoplastic cells and intestinal crypt stem cells, suggesting a potential role in cellular proliferation and differentiation. **Pathways and Functions:** The mechanisms underlying RN7SL214P's expression and function are not fully understood. However, several pathways may contribute to its expression: 1. **Non-coding RNA-mediated regulation:** RN7SL214P may interact with other non-coding RNAs to modulate gene expression, influencing cellular processes such as proliferation, differentiation, and survival. 2. **Epigenetic regulation:** RN7SL214P may participate in epigenetic modifications, affecting chromatin structure and gene expression. 3. **Cell signaling:** RN7SL214P may be involved in cell signaling pathways, influencing cell-cell communication and tissue homeostasis. Despite these hypotheses, the functional significance of RN7SL214P remains unclear. Further research is necessary to elucidate its role in cellular processes and disease. **Clinical Significance:** RN7SL214P's expression in neoplastic cells and intestinal crypt stem cells raises concerns about its potential involvement in cancer development and progression. Studies investigating RN7SL214P's expression in various cancers, including colorectal cancer, may provide insights into its clinical significance. Furthermore, RN7SL214P's expression in fibroblasts and neurons suggests a potential role in tissue repair and regeneration. Understanding the mechanisms underlying RN7SL214P's expression and function may lead to the development of novel therapeutic strategies for tissue repair and disease prevention. In conclusion, RN7SL214P is a pseudogene with complex expression patterns and potential functional implications. Further research is necessary to elucidate its role in cellular processes and disease, ultimately revealing its clinical significance and potential therapeutic applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.