Details for: OR10D1P

Gene ID: 26541

Symbol: OR10D1P

Ensembl ID: ENSG00000196403

Description: olfactory receptor family 10 subfamily D member 1 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.0368
    Cell Significance Index: 0.4500
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.0258
    Cell Significance Index: 0.2700
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.0118
    Cell Significance Index: 0.1100
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0.0107
    Cell Significance Index: 0.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0001
    Cell Significance Index: -0.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0001
    Cell Significance Index: -0.0100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0010
    Cell Significance Index: -0.0300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0010
    Cell Significance Index: -0.0300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0015
    Cell Significance Index: -0.0300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0015
    Cell Significance Index: -0.0300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0018
    Cell Significance Index: -0.0200
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0023
    Cell Significance Index: -0.0300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0029
    Cell Significance Index: -0.0300
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0066
    Cell Significance Index: -0.0900
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0071
    Cell Significance Index: -0.0400
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0100
    Cell Significance Index: -0.1100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0144
    Cell Significance Index: -0.1700
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0306
    Cell Significance Index: -0.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogenization:** OR10D1P is a pseudogenized member of the olfactory receptor family, resulting from a non-functional gene that has undergone degeneration. 2. **Significant expression:** OR10D1P is expressed in multiple cell types, including stromal cells, neurons, pancreatic acinar cells, and pigmented epithelial cells. 3. **Cellular localization:** The expression of OR10D1P is primarily found in cells involved in immune responses, tissue maintenance, and sensory perception. **Pathways and Functions:** 1. **Olfactory pathway:** Although OR10D1P is a pseudogenized member of the olfactory receptor family, it may still be involved in the olfactory pathway, potentially modulating the perception of odorant molecules. 2. **Immune responses:** OR10D1P expression in stromal cells and neurons suggests a potential role in modulating immune responses, possibly through the regulation of cytokine production or immune cell activation. 3. **Tissue maintenance:** The expression of OR10D1P in pancreatic acinar cells and pigmented epithelial cells implies a role in maintaining tissue homeostasis, potentially through the regulation of cell growth, differentiation, or survival. 4. **Neurotransmission:** OR10D1P expression in neurons may be involved in neurotransmission, potentially modulating the release of neurotransmitters or influencing synaptic plasticity. **Clinical Significance:** 1. **Immunological disorders:** The expression of OR10D1P in stromal cells and neurons suggests a potential link to immunological disorders, such as autoimmune diseases or inflammatory conditions. 2. **Cancer:** The expression of OR10D1P in pancreatic acinar cells and pigmented epithelial cells implies a potential role in cancer development or progression, particularly in pancreatic cancer. 3. **Neurological disorders:** OR10D1P expression in neurons may be involved in the pathogenesis of neurological disorders, such as Alzheimer's disease or Parkinson's disease. 4. **Olfactory disorders:** The presence of OR10D1P in the olfactory pathway may contribute to olfactory disorders, such as anosmia or hyposmia. In conclusion, the OR10D1P gene, despite its pseudogenized state, has significant implications for our understanding of immunological and neurological processes. Further research is necessary to elucidate the functional significance of OR10D1P and its potential role in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.