VNN1 | ENSG00000112299 | NCBI 8876

Details for: VNN1

Gene ID: 8876

Symbol: VNN1

Ensembl ID: ENSG00000112299

Description: vanin 1

Associated with

Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Metabolism
(R-HSA-1430728)
Metabolism of proteins
(R-HSA-392499)
Metabolism of vitamins and cofactors
(R-HSA-196854)
Metabolism of water-soluble vitamins and cofactors
(R-HSA-196849)
Neutrophil degranulation
(R-HSA-6798695)
Post-translational modification: synthesis of gpi-anchored proteins
(R-HSA-163125)
Post-translational protein modification
(R-HSA-597592)
Vitamin b5 (pantothenate) metabolism
(R-HSA-199220)
Acute inflammatory response
(GO:0002526)
Azurophil granule membrane
(GO:0035577)
Cell-cell adhesion
(GO:0098609)
Chronic inflammatory response
(GO:0002544)
Coenzyme a catabolic process
(GO:0015938)
Extracellular region
(GO:0005576)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Pantetheine hydrolase activity
(GO:0017159)
Pantothenate metabolic process
(GO:0015939)
Plasma membrane
(GO:0005886)
Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
(GO:1902177)
Positive regulation of t cell differentiation in thymus
(GO:0033089)
Response to oxidative stress
(GO:0006979)
Side of membrane
(GO:0098552)

Other Information

Proteins

Pantetheinase

Genular Protein ID: 1187008361

Symbol: VNN1_HUMAN

Name: Pantetheinase

UniProtKB Accession Codes:

O95497 A8K310 Q4JFW6 Q4VAS7 Q4VAS8 Q4VAS9 Q9UF16 Q9UJF4

Database IDs:

Citations:

PubMed ID: 9790769

Title: Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.

PubMed ID: 9790769

DOI: 10.1006/geno.1998.5481

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10567687

Title: Is pantetheinase the actual identity of mouse and human vanin-1 proteins?

PubMed ID: 10567687

DOI: 10.1016/s0014-5793(99)01439-8

PubMed ID: 11491533

Title: Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes.

PubMed ID: 11491533

DOI: 10.1007/s002510100327

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19322213

Title: Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines.

PubMed ID: 19322213

DOI: 10.1038/jid.2009.67

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 25478849

Title: The structure of vanin 1: a key enzyme linking metabolic disease and inflammation.

PubMed ID: 25478849

DOI: 10.1107/s1399004714022767

Sequence Information:

Length: 513
Mass: 57012
Checksum: 018D2417C12E403F
Sequence:

MTTQLPAYVA ILLFYVSRAS CQDTFTAAVY EHAAILPNAT LTPVSREEAL ALMNRNLDIL 
EGAITSAADQ GAHIIVTPED AIYGWNFNRD SLYPYLEDIP DPEVNWIPCN NRNRFGQTPV 
QERLSCLAKN NSIYVVANIG DKKPCDTSDP QCPPDGRYQY NTDVVFDSQG KLVARYHKQN 
LFMGENQFNV PKEPEIVTFN TTFGSFGIFT CFDILFHDPA VTLVKDFHVD TIVFPTAWMN 
VLPHLSAVEF HSAWAMGMRV NFLASNIHYP SKKMTGSGIY APNSSRAFHY DMKTEEGKLL 
LSQLDSHPSH SAVVNWTSYA SSIEALSSGN KEFKGTVFFD EFTFVKLTGV AGNYTVCQKD 
LCCHLSYKMS ENIPNEVYAL GAFDGLHTVE GRYYLQICTL LKCKTTNLNT CGDSAETAST 
RFEMFSLSGT FGTQYVFPEV LLSENQLAPG EFQVSTDGRL FSLKPTSGPV LTVTLFGRLY 
EKDWASNASS GLTAQARIIM LIVIAPIVCS LSW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: VNN1

Associated with

Other Information

Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6. PubMed ID: 9790769

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and analysis of human chromosome 6. PubMed ID: 14574404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Is pantetheinase the actual identity of mouse and human vanin-1 proteins? PubMed ID: 10567687

Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes. PubMed ID: 11491533

A proteomic analysis of human bile. PubMed ID: 15084671

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. PubMed ID: 19322213

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

The structure of vanin 1: a key enzyme linking metabolic disease and inflammation. PubMed ID: 25478849