Details for: OR5D3P

Gene ID: 8594

Symbol: OR5D3P

Ensembl ID: ENSG00000186886

Description: olfactory receptor family 5 subfamily D member 3 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.0700
    Cell Significance Index: 0.4900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0260
    Cell Significance Index: 0.7700
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.0114
    Cell Significance Index: 0.1000
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.0108
    Cell Significance Index: 0.1000
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.0064
    Cell Significance Index: 0.0700
  • Cell Name: adipocyte (CL0000136)
    Fold Change: 0.0045
    Cell Significance Index: 0.0600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0001
    Cell Significance Index: 0.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0008
    Cell Significance Index: -0.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0009
    Cell Significance Index: -0.2700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0032
    Cell Significance Index: -0.0600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0034
    Cell Significance Index: -0.0800
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0041
    Cell Significance Index: -0.0400
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0054
    Cell Significance Index: -0.0600
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: -0.0055
    Cell Significance Index: -0.0600
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0057
    Cell Significance Index: -0.0600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0060
    Cell Significance Index: -0.0800
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0061
    Cell Significance Index: -0.0600
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0061
    Cell Significance Index: -0.0600
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.0064
    Cell Significance Index: -0.0600
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0070
    Cell Significance Index: -0.0800
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: -0.0096
    Cell Significance Index: -0.0700
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0128
    Cell Significance Index: -0.1600
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0138
    Cell Significance Index: -0.1800
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0146
    Cell Significance Index: -0.1900
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0149
    Cell Significance Index: -0.1700
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0155
    Cell Significance Index: -0.1700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0156
    Cell Significance Index: -0.1700
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0159
    Cell Significance Index: -0.2100
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0175
    Cell Significance Index: -0.2300
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: -0.0199
    Cell Significance Index: -0.1800
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0202
    Cell Significance Index: -0.1900
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0215
    Cell Significance Index: -0.2100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0232
    Cell Significance Index: -0.2200
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0251
    Cell Significance Index: -0.2200
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.0461
    Cell Significance Index: -0.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene status**: OR5D3P is classified as a pseudogene, which suggests that it has undergone significant degeneration or loss of function compared to its functional counterparts. 2. **Wide tissue expression**: OR5D3P is expressed in multiple cell types, including those found in the immune system (e.g., neutrophils, T cells) and the nervous system (e.g., neurons, enterocytes). 3. **Specific neuronal subtype**: OR5D3P is specifically expressed in L2/3-6 intratelencephalic projecting glutamatergic neurons, a subtype of neurons involved in sensory processing. 4. **Evolutionary conservation**: Despite being a pseudogene, OR5D3P shows conservation across species, suggesting that it may have retained some functional or regulatory capacity. **Pathways and Functions:** 1. **Immune regulation**: OR5D3P's expression in immune cells (e.g., neutrophils, T cells) suggests that it may play a role in modulating immune responses or influencing the behavior of immune cells. 2. **Olfaction**: The expression of OR5D3P in neurons and enterocytes raises the possibility that it may contribute to olfactory perception or the processing of olfactory information. 3. **Neurotransmission**: OR5D3P's presence in glutamatergic neurons could imply a role in neurotransmission, potentially influencing synaptic plasticity or neuronal excitability. 4. **Gene regulation**: OR5D3P's expression in stromal cells and other non-neuronal cells may indicate that it serves as a regulator of gene expression, influencing the transcriptional landscape of these cells. **Clinical Significance:** 1. **Immunological disorders**: OR5D3P's expression in immune cells raises the possibility that it may be involved in the pathogenesis of immunological disorders, such as autoimmune diseases or allergies. 2. **Neurological disorders**: The expression of OR5D3P in neurons and enterocytes suggests that it may contribute to the development or progression of neurological disorders, such as Alzheimer's disease or Parkinson's disease. 3. **Olfactory disorders**: OR5D3P's association with olfactory perception and processing raises the possibility that it may be involved in the diagnosis or treatment of olfactory disorders, such as anosmia or hyposmia. 4. **Cancer research**: OR5D3P's expression in stromal cells and other non-neuronal cells may indicate that it serves as a tumor suppressor or oncogene, influencing cancer progression and metastasis. In conclusion, OR5D3P is a complex gene with a multifaceted expression pattern that challenges our current understanding of its functional significance. Further research is needed to elucidate the role of OR5D3P in immune regulation, olfaction, neurotransmission, and gene regulation, as well as its potential implications for human disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.