Cell ID: CL0000625

Cell Name: CD8-positive, alpha-beta T cell

CSI Thresholds:

Select	Context	Threshold
	Overall	9.4809
	Blood + Systemic lupus erythematosus	349.9931
	Systemic lupus erythematosus	349.7752
	Cortex of kidney + Healthy	261.9189
	B-cell non-Hodgkin lymphoma	174.6542
	Blood + B-cell non-Hodgkin lymphoma	154.6919
	Adrenal tissue + Healthy	147.3711
	Caudate lobe of liver + Healthy	109.3775
	Vein + Nonpapillary renal cell carcinoma	105.4118
	Vein	105.4058
	Nasopharynx + Healthy	101.5330
	Kidney + Nonpapillary renal cell carcinoma	88.6424
	Cortex of kidney	84.1180
	Tonsil + Healthy	67.4767
	Tonsil	66.8261
	Adrenal tissue	62.3773
	Pleural effusion + Lung adenocarcinoma	60.1780
	Breast + Breast carcinoma	59.5879
	Breast carcinoma	59.5182
	Bronchopulmonary lymph node + Healthy	58.6070
	Bronchopulmonary lymph node	58.5201
	Ileal epithelium + Healthy	57.9682
	Nonpapillary renal cell carcinoma	48.7435
	Saliva + COVID-19	48.3491
	Saliva	48.1587
	Adrenal tissue + Nonpapillary renal cell carcinoma	47.8494
	Lymph node + Follicular lymphoma	47.5241
	Follicular lymphoma	47.3268
	Lower lobe of left lung + Healthy	46.3189
	Lower lobe of left lung	46.2971
	Kidney oncocytoma	41.3336
	Kidney + Kidney oncocytoma	41.3278
	Primary sclerosing cholangitis	38.2105
	Caudate lobe of liver + Primary sclerosing cholangitis	38.1333
	Venous blood + Healthy	37.3630
	Venous blood	37.3232
	Ileal epithelium + Crohn disease	37.0595
	Prostate gland	36.2624
	Prostate gland + Healthy	36.2183
	Left colon + Crohn disease	35.1983
	Large intestine	35.0485
	Left colon	34.8808
	Parotid gland + Healthy	32.6482
	Colon + Healthy	32.6120
	Parotid gland	32.4877
	Caudate lobe of liver + Primary biliary cholangitis	32.2928
	Primary biliary cholangitis	32.2164
	Brain + Lung adenocarcinoma	32.1265
	Lung + Squamous cell lung carcinoma	31.2395
	Squamous cell lung carcinoma	31.1840
	Caecum + Healthy	30.9002
	Lamina propria of small intestine + Crohn disease	30.4439
	Lamina propria of mucosa of colon + Crohn disease	28.7806
	Lung adenocarcinoma	28.7673
	Lamina propria of mucosa of colon	28.7527
	Transverse colon + Healthy	27.9463
	Sigmoid colon + Crohn disease	27.8017
	Transverse colon	26.9997
	Cystic fibrosis	26.9469
	Lung + Cystic fibrosis	26.8985
	Influenza	26.6504
	Lung + Lung adenocarcinoma	25.2009
	Ileal epithelium	24.9318
	Colon	24.2003
	Invasive lobular breast carcinoma	24.1906
	Breast + Invasive lobular breast carcinoma	24.1613
	Bone marrow + Healthy	24.1107
	Lung + Pleomorphic carcinoma	22.8458
	Pleomorphic carcinoma	22.8413
	Clonal hematopoiesis	22.2051
	Blood + Clonal hematopoiesis	22.0642
	Pleural effusion	21.8892
	Kidney benign neoplasm	21.8579
	Kidney + Kidney benign neoplasm	21.6344
	Colon + Crohn disease	21.2530
	Epithelium of small intestine	20.7912
	Epithelium of small intestine + Crohn disease	20.7404
	Nasopharynx	20.3657
	Ileum	20.2807
	Lung parenchyma + Healthy	19.7789
	Caecum	19.5519
	Right colon	19.2903
	Right colon + Crohn disease	19.2406
	Breast	19.1948
	Lamina propria of small intestine	18.7392
	Lymph node + Lung adenocarcinoma	18.7318
	Kidney	17.8024
	Respiratory airway	16.5820
	Kidney + Healthy	16.5112
	Respiratory airway + Healthy	16.4969
	Lung + Lung large cell carcinoma	16.4422
	Lung large cell carcinoma	16.4307
	Bone marrow	16.3698
	Lung parenchyma	16.0195
	Sigmoid colon	15.9736
	Non-small cell lung carcinoma	15.7952
	Lung + Non-small cell lung carcinoma	15.7941
	Large intestine + Healthy	15.5373
	Caudate lobe of liver	15.1723
	Blood + Respiratory system disorder	15.1678
	Caecum + Crohn disease	15.1245
	Respiratory system disorder	15.0673
	Colonic epithelium	14.9038
	Colonic epithelium + Crohn disease	14.8956
	Caecum epithelium	14.3203
	Caecum epithelium + Crohn disease	14.2479
	Crohn disease	13.8972
	Ileum + Crohn disease	13.8156
	Renal cell carcinoma	13.6225
	Renal pelvis	13.4228
	Renal pelvis + Healthy	13.3772
	Lymph node	13.2519
	Small intestine + Healthy	13.1677
	Breast + Invasive ductal breast carcinoma	13.1503
	Invasive ductal breast carcinoma	13.1494
	Trachea + Healthy	11.9780
	Vermiform appendix + Healthy	11.6772
	Blood + COVID-19	11.5918
	Vermiform appendix	11.5674
	Small intestine + Crohn disease	11.3866
	Trachea	10.8937
	Small intestine	10.4818
	Lung + Renal cell carcinoma	9.9933
	Healthy	9.9683
	Blood + Influenza	9.8229
	Lung + Chronic obstructive pulmonary disease	9.6076
	Sigmoid colon + Healthy	9.4970
	Lung parenchyma + Chronic obstructive pulmonary disease	9.1033
	Mesenteric lymph node	8.8601
	Lung + Hypersensitivity pneumonitis	8.7824
	Mesenteric lymph node + Healthy	8.7767
	Renal medulla + Healthy	8.7633
	Hypersensitivity pneumonitis	8.7221
	Chronic obstructive pulmonary disease	8.0488
	Nasopharynx + COVID-19	7.9206
	Perirenal fat	7.6248
	Perirenal fat + Healthy	7.6059
	Nose + Healthy	7.4733
	Spleen	7.2594
	Spleen + Healthy	7.2410
	Blood	6.8271
	Brain	6.7245
	Metastatic melanoma	6.7009
	Lymph node + Metastatic melanoma	6.6732
	Lung + Non-specific interstitial pneumonia	6.2087
	Non-specific interstitial pneumonia	6.1815
	Ileum + Healthy	5.9690
	Intercostal muscle + Healthy	5.6527
	Intercostal muscle	5.6483
	COVID-19	5.2219
	Blood + Healthy	5.0720
	Lung + Interstitial lung disease	4.9429
	Lung + Lymphangioleiomyomatosis	4.9230
	Interstitial lung disease	4.9201
	Lymphangioleiomyomatosis	4.8477
	Nasopharynx + Respiratory failure	4.7500
	Respiratory failure	4.7251
	Pulmonary sarcoidosis	4.5660
	Lung + Pulmonary sarcoidosis	4.5643
	Renal medulla	4.5100
	Lung + COVID-19	4.4460
	Nose	3.5484
	Lung	3.4778
	Thymus + Healthy	3.2400
	Thymus	3.2360
	Pulmonary fibrosis	3.1815
	Pneumonia	3.1522
	Lung + Pulmonary fibrosis	3.1408
	Lung + Pneumonia	3.1406
	Lymph node + Healthy	2.9154
	Lung + Healthy	2.6946
	Nose + Chronic rhinitis	2.1015
	Chronic rhinitis	2.0787
	Nasopharynx + Long COVID-19	2.0238
	Long COVID-19	2.0155
	Muscle of abdomen	1.6300
	Muscle of abdomen + Healthy	1.6275
	Epithelium of esophagus + Healthy	0.9026
	Epithelium of esophagus	0.8982
	Muscle of pelvic diaphragm + Healthy	0.4471
	Muscle of pelvic diaphragm	0.4260
	Kidney + Renal cell carcinoma	0.0100
	Down syndrome	-1.0145
	Bone marrow + Down syndrome	-1.0157
	Eye	-4.6112
	Eye + Healthy	-4.8069
	Muscle tissue + Healthy	-8.3073
	Muscle tissue	-8.3277
	Sclera + Healthy	-26.2558
	Sclera	-26.3233
	Descending colon + Healthy	-89.3211
	Descending colon	-90.2192
	Ascending colon + Healthy	-156.9617
	Ascending colon	-162.5842

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.

Synonyms: CD8-positive, alpha-beta T lymphocyte, CD8-positive, alpha-beta T-cell, CD8-positive, alpha-beta T-lymphocyte