Details for: AHDC1

Gene ID: 27245

Symbol: AHDC1

Ensembl ID: ENSG00000126705

Description: AT-hook DNA binding motif containing 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 211.5140
    Cell Significance Index: -32.9000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 123.2636
    Cell Significance Index: -31.2700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 69.2405
    Cell Significance Index: -32.6900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 64.9096
    Cell Significance Index: -26.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.6200
    Cell Significance Index: -26.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 26.7974
    Cell Significance Index: -33.0400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.6281
    Cell Significance Index: -31.1500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.6494
    Cell Significance Index: -18.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.3831
    Cell Significance Index: -33.0800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.9409
    Cell Significance Index: -24.3900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.7423
    Cell Significance Index: 73.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.5544
    Cell Significance Index: 43.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4022
    Cell Significance Index: 281.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9925
    Cell Significance Index: 356.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7352
    Cell Significance Index: 56.4200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.7088
    Cell Significance Index: 18.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6397
    Cell Significance Index: 33.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5516
    Cell Significance Index: 24.4000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5479
    Cell Significance Index: 35.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5271
    Cell Significance Index: 364.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4909
    Cell Significance Index: 18.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4755
    Cell Significance Index: 24.7000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4748
    Cell Significance Index: 21.5200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4201
    Cell Significance Index: 83.3600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4099
    Cell Significance Index: 181.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4046
    Cell Significance Index: 55.5700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3771
    Cell Significance Index: 10.8700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3485
    Cell Significance Index: 18.3000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3191
    Cell Significance Index: 288.1400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2505
    Cell Significance Index: 47.6700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2339
    Cell Significance Index: 15.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2253
    Cell Significance Index: 4.8800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2241
    Cell Significance Index: 22.1700
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.2225
    Cell Significance Index: 3.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1777
    Cell Significance Index: 21.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1723
    Cell Significance Index: 8.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1672
    Cell Significance Index: 91.2900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1613
    Cell Significance Index: 26.2400
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.1552
    Cell Significance Index: 1.0300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1337
    Cell Significance Index: 24.1100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1320
    Cell Significance Index: 2.8900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1225
    Cell Significance Index: 2.1000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1195
    Cell Significance Index: 3.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0966
    Cell Significance Index: 6.8300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0909
    Cell Significance Index: 167.7300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0736
    Cell Significance Index: 8.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0604
    Cell Significance Index: 113.7600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0474
    Cell Significance Index: 6.1300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0451
    Cell Significance Index: 2.7800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0415
    Cell Significance Index: 56.3900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0326
    Cell Significance Index: 50.1300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0246
    Cell Significance Index: 15.6100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0229
    Cell Significance Index: 0.8100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0134
    Cell Significance Index: 1.0000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0118
    Cell Significance Index: 5.3600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0007
    Cell Significance Index: 0.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0027
    Cell Significance Index: -1.9800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0044
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0068
    Cell Significance Index: -5.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0089
    Cell Significance Index: -1.3000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0191
    Cell Significance Index: -11.9000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0302
    Cell Significance Index: -0.5900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0422
    Cell Significance Index: -31.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0425
    Cell Significance Index: -23.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0457
    Cell Significance Index: -5.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0463
    Cell Significance Index: -2.6000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0475
    Cell Significance Index: -2.8500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0769
    Cell Significance Index: -8.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0821
    Cell Significance Index: -5.6800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0834
    Cell Significance Index: -10.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0862
    Cell Significance Index: -18.1600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0995
    Cell Significance Index: -28.6300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1210
    Cell Significance Index: -12.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1488
    Cell Significance Index: -17.3400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1686
    Cell Significance Index: -7.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1796
    Cell Significance Index: -3.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2146
    Cell Significance Index: -5.8400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2162
    Cell Significance Index: -2.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2215
    Cell Significance Index: -26.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2656
    Cell Significance Index: -27.6600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2745
    Cell Significance Index: -5.7000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3262
    Cell Significance Index: -9.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3333
    Cell Significance Index: -26.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3367
    Cell Significance Index: -11.7000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3468
    Cell Significance Index: -9.1200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3723
    Cell Significance Index: -2.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3728
    Cell Significance Index: -22.8600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3940
    Cell Significance Index: -9.4500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4324
    Cell Significance Index: -10.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4719
    Cell Significance Index: -12.6000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4755
    Cell Significance Index: -29.9700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4811
    Cell Significance Index: -6.8900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4850
    Cell Significance Index: -24.5100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5066
    Cell Significance Index: -12.3600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5073
    Cell Significance Index: -7.4900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5093
    Cell Significance Index: -10.6600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5191
    Cell Significance Index: -7.4600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5240
    Cell Significance Index: -16.6900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5385
    Cell Significance Index: -17.6300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.5413
    Cell Significance Index: -11.5700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AHDC1 is a transcriptional regulator that utilizes an AT-hook DNA binding motif to interact with specific DNA sequences. Its expression is widespread, with notable presence in cortical neurons, astrocytes, and skeletal muscle cells. The gene's involvement in neuronal and muscle cell development highlights its potential role in regulating cellular differentiation, morphogenesis, and survival. The AT-hook motif, characteristic of AHDC1, is a unique feature that distinguishes this gene from other transcription factors. **Pathways and Functions:** AHDC1's involvement in various cellular processes can be attributed to its participation in several key pathways: 1. **Cell differentiation**: AHDC1 regulates the expression of genes involved in neuronal and muscle cell differentiation, ensuring proper cellular development and function. 2. **Chromatin remodeling**: The AT-hook motif of AHDC1 facilitates chromatin remodeling, allowing for the dynamic regulation of gene expression and the establishment of distinct cellular identities. 3. **Transcriptional regulation**: AHDC1 modulates the expression of target genes, influencing cellular processes such as proliferation, survival, and differentiation. 4. **Promoter-enhancer loop anchoring**: AHDC1's interaction with specific DNA sequences enables the formation of promoter-enhancer loops, a crucial mechanism for regulating gene expression and cellular identity. **Clinical Significance:** The identification of AHDC1's role in neuronal and muscle cell development has significant implications for our understanding of neurodegenerative diseases and muscular disorders. Dysregulation of AHDC1 has been implicated in various conditions, including: 1. **Neurodevelopmental disorders**: Mutations in AHDC1 have been linked to neurological disorders, such as autism spectrum disorder and schizophrenia, highlighting the gene's importance in neuronal development and function. 2. **Muscular dystrophy**: AHDC1's involvement in muscle cell development and maintenance suggests that dysregulation of this gene may contribute to muscular dystrophy and other muscle-related disorders. 3. **Cancer**: The transcriptional regulatory functions of AHDC1 may also be relevant in the context of cancer, where dysregulation of this gene could contribute to tumorigenesis and cancer progression. In conclusion, AHDC1 is a complex gene that plays a critical role in regulating cellular development, differentiation, and function. Further research into the molecular mechanisms underlying AHDC1's functions will provide valuable insights into the pathogenesis of neurodegenerative diseases, muscular disorders, and cancer, ultimately leading to the development of novel therapeutic strategies.

Genular Protein ID: 377094437

Symbol: AHDC1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5TGY3 Q5TGY4 Q6PJK1 Q6ZUQ6 Q99769 Q9NUF5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 6 GO 7 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 9 SIGNOR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

DOI: 10.1101/gr.7.4.353

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24791903

Title: De novo truncating mutations in AHDC1 in individuals with syndromic expressive language delay, hypotonia, and sleep apnea.

PubMed ID: 24791903

DOI: 10.1016/j.ajhg.2014.04.006

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 29230160

Title: Whole-exome sequencing identifies a de novo AHDC1 mutation in a colombian patient with Xia-Gibbs syndrome.

PubMed ID: 29230160

DOI: 10.1159/000479357

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31182893

Title: Syndromic Intellectual Disability Caused by a Novel Truncating Variant in AHDC1: A Case Report.

PubMed ID: 31182893

PubMed ID: 27148574

Title: De novo truncating variants in the AHDC1 gene encoding the AT-hook DNA-binding motif-containing protein 1 are associated with intellectual disability and developmental delay.

PubMed ID: 27148574

DOI: 10.1101/mcs.a000562

PubMed ID: 29696776

Title: The phenotypic spectrum of Xia-Gibbs syndrome.

PubMed ID: 29696776

DOI: 10.1002/ajmg.a.38699

PubMed ID: 30152016

Title: Variable clinical manifestations of Xia-Gibbs syndrome: findings of consecutively identified cases at a single children's hospital.

PubMed ID: 30152016

DOI: 10.1002/ajmg.a.40380

PubMed ID: 30622101

Title: Xia-Gibbs syndrome in adulthood: a case report with insight into the natural history of the condition.

PubMed ID: 30622101

DOI: 10.1101/mcs.a003608

PubMed ID: 30729726

Title: Two Chinese Xia-Gibbs syndrome patients with partial growth hormone deficiency.

PubMed ID: 30729726

DOI: 10.1002/mgg3.596

PubMed ID: 30858058

Title: Extending the phenotype of Xia-Gibbs syndrome in a two-year-old patient with craniosynostosis with a novel de novo AHDC1 missense mutation.

PubMed ID: 30858058

DOI: 10.1016/j.ejmg.2019.03.001

PubMed ID: 32256298

Title: Novel AHDC1 gene mutation in a brazilian individual: implications of Xia-Gibbs syndrome.

PubMed ID: 32256298

DOI: 10.1159/000505843

PubMed ID: 34229113

Title: Phenotypic heterogeneity and mosaicism in Xia-Gibbs syndrome: Five Danish patients with novel variants in AHDC1.

PubMed ID: 34229113

DOI: 10.1016/j.ejmg.2021.104280

PubMed ID: 34950897

Title: AHDC1 missense mutations in Xia-Gibbs syndrome.

PubMed ID: 34950897

DOI: 10.1016/j.xhgg.2021.100049

PubMed ID: 33644933

Title: Phenotypic and protein localization heterogeneity associated with AHDC1 pathogenic protein-truncating alleles in Xia-Gibbs syndrome.

PubMed ID: 33644933

DOI: 10.1002/humu.24190

PubMed ID: 35585237

Title: Gibbin mesodermal regulation patterns epithelial development.

PubMed ID: 35585237

DOI: 10.1038/s41586-022-04727-9

Sequence Information:

  • Length: 1603
  • Mass: 168349
  • Checksum: 2BAC8DC14836F493
  • Sequence:
    • MRVKPQGLVV TSSAVCSSPD YLREPKYYPG GPPTPRPLLP TRPPASPPDK AFSTHAFSEN 
PRPPPRRDPS TRRPPVLAKG DDPLPPRAAR PVSQARCPTP VGDGSSSRRC WDNGRVNLRP 
VVQLIDIMKD LTRLSQDLQH SGVHLDCGGL RLSRPPAPPP GDLQYSFFSS PSLANSIRSP 
EERATPHAKS ERPSHPLYEP EPEPRDSPQP GQGHSPGATA AATGLPPEPE PDSTDYSELA 
DADILSELAS LTCPEAQLLE AQALEPPSPE PEPQLLDPQP RFLDPQALEP LGEALELPPL 
QPLADPLGLP GLALQALDTL PDSLESQLLD PQALDPLPKL LDVPGRRLEP QQPLGHCPLA 
EPLRLDLCSP HGPPGPEGHP KYALRRTDRP KILCRRRKAG RGRKADAGPE GRLLPLPMPT 
GLVAALAEPP PPPPPPPPAL PGPGPVSVPE LKPESSQTPV VSTRKGKCRG VRRMVVKMAK 
IPVSLGRRNK TTYKVSSLSS SLSVEGKELG LRVSAEPTPL LKMKNNGRNV VVVFPPGEMP 
IILKRKRGRP PKNLLLGPGK PKEPAVVAAE AATVAAATMA MPEVKKRRRR KQKLASPQPS 
YAADANDSKA EYSDVLAKLA FLNRQSQCAG RCSPPRCWTP SEPESVHQAP DTQSISHFLH 
RVQGFRRRGG KAGGFGGRGG GHAAKSARCS FSDFFEGIGK KKKVVAVAAA GVGGPGLTEL 
GHPRKRGRGE VDAVTGKPKR KRRSRKNGTL FPEQVPSGPG FGEAGAEWAG DKGGGWAPHH 
GHPGGQAGRN CGFQGTEARA FASTGLESGA SGRGSYYSTG APSGQTELSQ ERQNLFTGYF 
RSLLDSDDSS DLLDFALSAS RPESRKASGT YAGPPTSALP AQRGLATFPS RGAKASPVAV 
GSSGAGADPS FQPVLSARQT FPPGRAASYG LTPAASDCRA AETFPKLVPP PSAMARSPTT 
HPPANTYLPQ YGGYGAGQSV FAPTKPFTGQ DCANSKDCSF AYGSGNSLPA SPSSAHSAGY 
APPPTGGPCL PPSKASFFSS SEGAPFSGSA PTPLRCDSRA STVSPGGYMV PKGTTASATS 
AASAASSSSS SFQPSPENCR QFAGASQWPF RQGYGGLDWA SEAFSQLYNP SFDCHVSEPN 
VILDISNYTP QKVKQQTAVS ETFSESSSDS TQFNQPVGGG GFRRANSEAS SSEGQSSLSS 
LEKLMMDWNE ASSAPGYNWN QSVLFQSSSK PGRGRRKKVD LFEASHLGFP TSASAAASGY 
PSKRSTGPRQ PRGGRGGGAC SAKKERGGAA AKAKFIPKPQ PVNPLFQDSP DLGLDYYSGD 
SSMSPLPSQS RAFGVGERDP CDFIGPYSMN PSTPSDGTFG QGFHCDSPSL GAPELDGKHF 
PPLAHPPTVF DAGLQKAYSP TCSPTLGFKE ELRPPPTKLA ACEPLKHGLQ GASLGHAAAA 
QAHLSCRDLP LGQPHYDSPS CKGTAYWYPP GSAARSPPYE GKVGTGLLAD FLGRTEAACL 
SAPHLASPPA TPKADKEPLE MARPPGPPRG PAAAAAGYGC PLLSDLTLSP VPRDSLLPLQ 
DTAYRYPGFM PQAHPGLGGG PKSGFLGPMA EPHPEDTFTV TSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.