Details for: SNORD55

Gene ID: 26811

Symbol: SNORD55

Ensembl ID: ENSG00000264294

Description: small nucleolar RNA, C/D box 55

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.5548
    Cell Significance Index: 7.1300
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.1777
    Cell Significance Index: 2.1500
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.1530
    Cell Significance Index: 1.9200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0212
    Cell Significance Index: 0.2500
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0005
    Cell Significance Index: -0.1300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0014
    Cell Significance Index: -0.0700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0035
    Cell Significance Index: -0.0400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0039
    Cell Significance Index: -0.0300
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0067
    Cell Significance Index: -0.0900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0073
    Cell Significance Index: -0.0800
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0076
    Cell Significance Index: -0.0800
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0077
    Cell Significance Index: -0.1000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0095
    Cell Significance Index: -0.1200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0100
    Cell Significance Index: -0.1300
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0101
    Cell Significance Index: -0.0900
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0103
    Cell Significance Index: -0.1100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0105
    Cell Significance Index: -0.1200
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0105
    Cell Significance Index: -0.1200
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0110
    Cell Significance Index: -0.1300
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0111
    Cell Significance Index: -0.1300
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0114
    Cell Significance Index: -0.1300
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.0114
    Cell Significance Index: -0.1200
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0127
    Cell Significance Index: -0.1500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0127
    Cell Significance Index: -0.1500
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0128
    Cell Significance Index: -0.1100
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.0130
    Cell Significance Index: -0.0900
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0133
    Cell Significance Index: -0.1600
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0138
    Cell Significance Index: -0.1600
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.0144
    Cell Significance Index: -0.1700
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0185
    Cell Significance Index: -0.2300
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0211
    Cell Significance Index: -0.1700
  • Cell Name: basket cell (CL0000118)
    Fold Change: -0.0269
    Cell Significance Index: -0.1300
  • Cell Name: serotonergic neuron (CL0000850)
    Fold Change: -0.0557
    Cell Significance Index: -0.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORD55 is a C/D box snoRNA, a class of small nucleolar RNAs that are involved in RNA processing and modification. These snoRNAs bind to specific target RNAs, guiding them through the processing pathways and modifying them to regulate their function. SNORD55 is specifically expressed in plasma cells, a type of immune cell responsible for producing antibodies, suggesting its involvement in regulating antibody production. Additionally, its expression in other cell types, such as cardiac endothelial cells and macrophages, indicates its potential role in regulating cellular differentiation and immune responses. **Pathways and Functions:** The pathways and functions of SNORD55 are not yet fully understood, but preliminary studies suggest its involvement in regulating RNA processing pathways. Specifically, SNORD55 is thought to bind to specific target RNAs, guiding them through the processing pathways and modifying them to regulate their function. This regulation is crucial for maintaining proper cellular differentiation and immune responses. For example, SNORD55 may play a role in regulating the expression of genes involved in antibody production, inflammation, and immune cell development. **Clinical Significance:** The clinical significance of SNORD55 is an area of ongoing research. Given its expression in plasma cells, a type of immune cell involved in regulating immune responses, alterations in SNORD55 expression may contribute to immune-related disorders. For example, SNORD55 may play a role in regulating antibody production, which is disrupted in autoimmune diseases such as rheumatoid arthritis and lupus. Additionally, its expression in cardiac endothelial cells and macrophages suggests its potential role in regulating cardiovascular and inflammatory responses. Further research is necessary to fully elucidate the clinical significance of SNORD55, but preliminary findings suggest its potential as a therapeutic target for immune-related disorders. **Conclusion:** In conclusion, SNORD55 is a small nucleolar RNA that plays a crucial role in regulating RNA processing pathways and cellular differentiation. Its expression in various cell types, including plasma cells, cardiac endothelial cells, and macrophages, highlights its importance in immune responses and tissue development. Further research is necessary to fully elucidate the functions of SNORD55, but preliminary findings suggest its potential as a therapeutic target for immune-related disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.