Details for: CHP2

Gene ID: 63928

Symbol: CHP2

Ensembl ID: ENSG00000166869

Description: calcineurin like EF-hand protein 2

Associated with

Other Information

Genular Protein ID: 1218170557

Symbol: CHP2_HUMAN

Name: Calcineurin B homologous protein 2

UniProtKB Accession Codes:

O43745 A8K2I8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTC 1 CTD 1 ChEBI 9 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12097419

Title: Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.

PubMed ID: 12097419

DOI: 10.4049/jimmunol.169.2.1102

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 12226101

Title: Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.

PubMed ID: 12226101

DOI: 10.1074/jbc.m208313200

PubMed ID: 18815128

Title: CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.

PubMed ID: 18815128

DOI: 10.1074/jbc.m806684200

PubMed ID: 21392185

Title: Nuclear accumulation of calcineurin B homologous protein 2 (CHP2) results in enhanced proliferation of tumor cells.

PubMed ID: 21392185

DOI: 10.1111/j.1365-2443.2011.01497.x

PubMed ID: 16511206

Title: Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE1.

PubMed ID: 16511206

DOI: 10.1107/s1744309105030836

PubMed ID: 16710297

Title: Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation.

PubMed ID: 16710297

DOI: 10.1038/sj.emboj.7601145

Sequence Information:

  • Length: 196
  • Mass: 22452
  • Checksum: F5113D558AFA27DE
  • Sequence:
    • MGSRSSHAAV IPDGDSIRRE TGFSQASLLR LHHRFRALDR NKKGYLSRMD LQQIGALAVN 
PLGDRIIESF FPDGSQRVDF PGFVRVLAHF RPVEDEDTET QDPKKPEPLN SRRNKLHYAF 
QLYDLDRDGK ISRHEMLQVL RLMVGVQVTE EQLENIADRT VQEADEDGDG AVSFVEFTKS 
LEKMDVEQKM SIRILK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.