Gene TRBV21OR9 2 - ENSG00000183938 | NCBI Gene ID: 6959

Details for: TRBV21OR9 2

Gene ID: 6959

Symbol: TRBV21OR9 2

Ensembl ID: ENSG00000183938

Description: T cell receptor beta variable 21/OR9-2 (pseudogene)

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Other Information

Description

**Key characteristics:** - TRBV21OR9-2 is a pseudogene, meaning it is an inactive gene that is not expressed in normal cells. - It is highly expressed in cells that are involved in immune responses. - It is a member of the TRBV21 family of immune receptors. **Pathways and functions:** TRBV21OR9-2 is a member of the TRBV21 family of immune receptors, which are expressed on the surface of lymphocytes. TRBV21s are involved in regulating the immune response by interacting with MHC molecules on antigen-presenting cells. When TRBV21s bind to MHC molecules, it triggers intracellular signaling pathways that lead to the activation of T cells. **Clinical significance:** TRBV21OR9-2 is a potential therapeutic target for cancer immunotherapy. Studies have shown that blocking the expression of TRBV21OR9-2 on cancer cells can inhibit their growth and metastasis. This approach is being investigated in clinical trials for the treatment of various cancers, including leukemia, lung cancer, and breast cancer.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.