BMAL2 | ENSG00000029153 | NCBI 56938

Details for: BMAL2

Gene ID: 56938

Symbol: BMAL2

Ensembl ID: ENSG00000029153

Description: basic helix-loop-helix ARNT like 2

Associated with

Bmal1:clock,npas2 activates circadian gene expression
(R-HSA-1368108)
Circadian clock
(R-HSA-400253)
Aryl hydrocarbon receptor complex
(GO:0034751)
Chromatin
(GO:0000785)
Circadian regulation of gene expression
(GO:0032922)
Circadian rhythm
(GO:0007623)
Clock-bmal transcription complex
(GO:1990513)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
E-box binding
(GO:0070888)
Entrainment of circadian clock
(GO:0009649)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of circadian rhythm
(GO:0042753)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein dimerization activity
(GO:0046983)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)

Other Information

Proteins

Aryl hydrocarbon receptor nuclear translocator-like protein 2

Genular Protein ID: 249771936

Symbol: BMAL2_HUMAN

Name: Aryl hydrocarbon receptor nuclear translocator-like protein 2

UniProtKB Accession Codes:

Q8WYA1 B7Z429 F5H402 Q8WYA2 Q8WYA3 Q8WYA4 Q96J63 Q9H2M4 Q9NS70 Q9NYQ4 Q9NYQ5

Database IDs:

Citations:

PubMed ID: 10964693

Title: cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2; Its mRNA expression, subcellular distribution, and chromosomal localization.

PubMed ID: 10964693

DOI: 10.1006/bbrc.2000.3248

PubMed ID: 11018023

Title: CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression.

PubMed ID: 11018023

DOI: 10.1074/jbc.c000629200

PubMed ID: 10864977

Title: The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors.

PubMed ID: 10864977

DOI: 10.1523/jneurosci.20-13-j0002.2000

PubMed ID: 11554928

Title: Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation.

PubMed ID: 11554928

DOI: 10.1046/j.1365-2443.2001.00462.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12738229

Title: Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2.

PubMed ID: 12738229

DOI: 10.1016/s0022-2828(03)00051-8

PubMed ID: 14672706

Title: A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation.

PubMed ID: 14672706

DOI: 10.1016/j.bbrc.2003.11.099

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

Length: 636
Mass: 70887
Checksum: 972CE2BC5B05B1F3
Sequence:

MAAEEEAAAG GKVLREENQC IAPVVSSRVS PGTRPTAMGS FSSHMTEFPR KRKGSDSDPS 
QSGIMTEKVV EKLSQNPLTY LLSTRIEISA SSGSRVEDGE HQVKMKAFRE AHSQTEKRRR 
DKMNNLIEEL SAMIPQCNPM ARKLDKLTVL RMAVQHLRSL KGLTNSYVGS NYRPSFLQDN 
ELRHLILKTA EGFLFVVGCE RGKILFVSKS VSKILNYDQA SLTGQSLFDF LHPKDVAKVK 
EQLSSFDISP REKLIDAKTG LQVHSNLHAG RTRVYSGSRR SFFCRIKSCK ISVKEEHGCL 
PNSKKKEHRK FYTIHCTGYL RSWPPNIVGM EEERNSKKDN SNFTCLVAIG RLQPYIVPQN 
SGEINVKPTE FITRFAVNGK FVYVDQRATA ILGYLPQELL GTSCYEYFHQ DDHNNLTDKH 
KAVLQSKEKI LTDSYKFRAK DGSFVTLKSQ WFSFTNPWTK ELEYIVSVNT LVLGHSEPGE 
ASFLPCSSQS SEESSRQSCM SVPGMSTGTV LGAGSIGTDI ANEILDLQRL QSSSYLDDSS 
PTGLMKDTHT VNCRSMSNKE LFPPSPSEMG ELEATRQNQS TVAVHSHEPL LSDGAQLDFD 
ALCDNDDTAM AAFMNYLEAE GGLGDPGDFS DIQWTL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: BMAL2

Associated with

Other Information

cDNA cloning of a novel bHLH-PAS transcription factor superfamily gene, BMAL2; Its mRNA expression, subcellular distribution, and chromosomal localization. PubMed ID: 10964693

CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. PubMed ID: 11018023

The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. PubMed ID: 10864977

Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation. PubMed ID: 11554928

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The finished DNA sequence of human chromosome 12. PubMed ID: 16541075

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2. PubMed ID: 12738229

A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. PubMed ID: 14672706

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733