WIF1 | ENSG00000156076 | NCBI 11197

Details for: WIF1

Gene ID: 11197

Symbol: WIF1

Ensembl ID: ENSG00000156076

Description: WNT inhibitory factor 1

Associated with

Negative regulation of tcf-dependent signaling by wnt ligand antagonists
(R-HSA-3772470)
Signaling by wnt
(R-HSA-195721)
Tcf dependent signaling in response to wnt
(R-HSA-201681)
Activin receptor binding
(GO:0070697)
Anterior/posterior pattern specification
(GO:0009952)
Blood vessel development
(GO:0001568)
Cell surface
(GO:0009986)
Determination of left/right symmetry
(GO:0007368)
Extracellular region
(GO:0005576)
Heart development
(GO:0007507)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nodal binding
(GO:0038100)
Nodal signaling pathway
(GO:0038092)
Positive regulation of fat cell differentiation
(GO:0045600)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)
Wnt-protein binding
(GO:0017147)
Wnt signaling pathway
(GO:0016055)

Other Information

Proteins

Wnt inhibitory factor 1

Genular Protein ID: 2712160998

Symbol: WIF1_HUMAN

Name: Wnt inhibitory factor 1

UniProtKB Accession Codes:

Q9Y5W5 Q6UXI1 Q8WVG4

Database IDs:

Citations:

PubMed ID: 10201374

Title: A new secreted protein that binds to Wnt proteins and inhibits their activities.

PubMed ID: 10201374

DOI: 10.1038/18899

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19188438

Title: Myocilin is a modulator of Wnt signaling.

PubMed ID: 19188438

DOI: 10.1128/mcb.01274-08

PubMed ID: 16476441

Title: NMR structure of the WIF domain of the human Wnt-inhibitory factor-1.

PubMed ID: 16476441

DOI: 10.1016/j.jmb.2006.01.047

Sequence Information:

Length: 379
Mass: 41528
Checksum: 32ADFA6644833E9D
Sequence:

MARRSAFPAA ALWLWSILLC LLALRAEAGP PQEESLYLWI DAHQARVLIG FEEDILIVSE 
GKMAPFTHDF RKAQQRMPAI PVNIHSMNFT WQAAGQAEYF YEFLSLRSLD KGIMADPTVN 
VPLLGTVPHK ASVVQVGFPC LGKQDGVAAF EVDVIVMNSE GNTILQTPQN AIFFKTCQQA 
ECPGGCRNGG FCNERRICEC PDGFHGPHCE KALCTPRCMN GGLCVTPGFC ICPPGFYGVN 
CDKANCSTTC FNGGTCFYPG KCICPPGLEG EQCEISKCPQ PCRNGGKCIG KSKCKCSKGY 
QGDLCSKPVC EPGCGAHGTC HEPNKCQCQE GWHGRHCNKR YEASLIHALR PAGAQLRQHT 
PSLKKAEERR DPPESNYIW

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: WIF1

Associated with

Other Information

A new secreted protein that binds to Wnt proteins and inhibits their activities. PubMed ID: 10201374

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334