Details for: SNORD51

Gene ID: 26798

Symbol: SNORD51

Ensembl ID: ENSG00000207047

Description: small nucleolar RNA, C/D box 51

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0021
    Cell Significance Index: -0.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0033
    Cell Significance Index: -0.3800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0084
    Cell Significance Index: -0.3800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0099
    Cell Significance Index: -0.5200
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0112
    Cell Significance Index: -0.1400
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0128
    Cell Significance Index: -0.1100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0156
    Cell Significance Index: -0.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0165
    Cell Significance Index: -0.4800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0173
    Cell Significance Index: -0.3600
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.0202
    Cell Significance Index: -0.1400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0262
    Cell Significance Index: -0.3400
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.0318
    Cell Significance Index: -0.3300
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -0.0381
    Cell Significance Index: -0.3700
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0428
    Cell Significance Index: -0.5200
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0445
    Cell Significance Index: -0.6000
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0448
    Cell Significance Index: -0.4400
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0460
    Cell Significance Index: -0.6000
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0462
    Cell Significance Index: -0.3200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0471
    Cell Significance Index: -0.5500
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0498
    Cell Significance Index: -0.5700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0507
    Cell Significance Index: -0.6400
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0516
    Cell Significance Index: -0.5900
  • Cell Name: brain vascular cell (CL4023072)
    Fold Change: -0.0534
    Cell Significance Index: -0.6100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0551
    Cell Significance Index: -0.6000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0554
    Cell Significance Index: -0.6600
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0560
    Cell Significance Index: -0.6000
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: -0.0600
    Cell Significance Index: -0.5200
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0614
    Cell Significance Index: -0.6900
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0651
    Cell Significance Index: -0.6200
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.0716
    Cell Significance Index: -0.8400
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.0746
    Cell Significance Index: -0.9300
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0790
    Cell Significance Index: -0.8100
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0801
    Cell Significance Index: -0.8100
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0806
    Cell Significance Index: -0.7600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0818
    Cell Significance Index: -0.9800
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.0851
    Cell Significance Index: -0.5900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.1022
    Cell Significance Index: -1.0900
  • Cell Name: basket cell (CL0000118)
    Fold Change: -0.1102
    Cell Significance Index: -0.5300
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.1115
    Cell Significance Index: -1.0400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORD51, with an Ensembl ID of ENSG00000207047, is a small nucleolar RNA belonging to the C/D box snoRNA family. These snoRNAs are primarily involved in the modification of ribosomal RNA (rRNA) during the processing of pre-rRNA. SNORD51, in particular, has been found to be significantly expressed in a diverse range of cell types, including pericytes, cardiac endothelial cells, cardiac muscle myoblasts, and various lineage-restricted progenitor cells. This widespread expression suggests that SNORD51 may play a role in maintaining cellular homeostasis and regulating cellular differentiation. **Pathways and Functions:** The primary function of SNORD51 is to participate in the RNA modification process, specifically the pseudouridylation of rRNA. This process involves the addition of a pseudouridine residue to specific positions on the rRNA, which is essential for ribosome function and stability. SNORD51 has been shown to interact with the pseudouridylation machinery, facilitating the modification of rRNA. Beyond its role in RNA processing, SNORD51 may also influence cellular differentiation, proliferation, and survival. Its expression in various tissue-specific cell types suggests that SNORD51 may play a role in regulating cellular behavior and tissue development. **Clinical Significance:** The clinical significance of SNORD51 is an area of ongoing research. While its expression in various tissues suggests that SNORD51 may be involved in disease pathogenesis, the specific mechanisms by which it contributes to disease are not yet fully understood. However, studies have implicated SNORD51 in the regulation of cellular behavior in various disease models, including cardiovascular disease, cancer, and immune disorders. For example, altered expression of SNORD51 has been observed in patients with cardiovascular disease and cancer, suggesting that it may serve as a biomarker for disease diagnosis or prognosis. Furthermore, SNORD51 may also play a role in modulating the immune response, given its expression in various immune cell types. In conclusion, SNORD51 is a small nucleolar RNA with a complex expression profile and potential implications in various cellular processes. Further research is needed to fully elucidate the mechanisms by which SNORD51 regulates cellular behavior and tissue development, as well as its clinical significance in disease diagnosis and treatment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.