Details for: ANO1

Gene ID: 55107

Symbol: ANO1

Ensembl ID: ENSG00000131620

Description: anoctamin 1

Associated with

Other Information

Genular Protein ID: 3770625937

Symbol: ANO1_HUMAN

Name: Anoctamin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16906560

Title: Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma.

PubMed ID: 16906560

DOI: 10.1002/gcc.20371

PubMed ID: 26359375

Title: A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.

PubMed ID: 26359375

DOI: 10.1152/ajpgi.00074.2015

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12739008

Title: FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.

PubMed ID: 12739008

PubMed ID: 15215166

Title: The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status.

PubMed ID: 15215166

DOI: 10.1016/s0002-9440(10)63279-8

PubMed ID: 20056604

Title: Expression and function of epithelial anoctamins.

PubMed ID: 20056604

DOI: 10.1074/jbc.m109.065367

PubMed ID: 21186280

Title: TMEM16A protein: a new identity for Ca(2+)-dependent Cl? channels.

PubMed ID: 21186280

DOI: 10.1152/physiol.00030.2010

PubMed ID: 21642943

Title: Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?

PubMed ID: 21642943

DOI: 10.1038/aps.2011.48

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22178883

Title: CFTR and TMEM16A are separate but functionally related Cl-channels.

PubMed ID: 22178883

DOI: 10.1159/000335765

PubMed ID: 21056985

Title: Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A.

PubMed ID: 21056985

DOI: 10.1074/jbc.m110.174847

PubMed ID: 21607626

Title: Anoctamins.

PubMed ID: 21607626

DOI: 10.1007/s00424-011-0975-9

PubMed ID: 22302790

Title: The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age.

PubMed ID: 22302790

DOI: 10.1113/expphysiol.2011.058214

PubMed ID: 21984732

Title: The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.

PubMed ID: 21984732

DOI: 10.1113/expphysiol.2011.058198

PubMed ID: 21908539

Title: Expression and function of epithelial anoctamins.

PubMed ID: 21908539

DOI: 10.1113/expphysiol.2011.058206

PubMed ID: 22946059

Title: Anoctamins are a family of Ca2+ activated Cl- channels.

PubMed ID: 22946059

DOI: 10.1242/jcs.109553

PubMed ID: 24913262

Title: TMEM16A is a Ca(2+) -activated Cl(-) channel expressed in the renal collecting duct.

PubMed ID: 24913262

DOI: 10.1111/apha.12323

PubMed ID: 25220078

Title: A novel TMEM16A splice variant lacking the dimerization domain contributes to calcium-activated chloride secretion in human sweat gland epithelial cells.

PubMed ID: 25220078

DOI: 10.1111/exd.12543

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28559167

Title: The stoichiometry of the TMEM16A ion channel determined in intact plasma membranes of COS-7 cells using liquid-phase electron microscopy.

PubMed ID: 28559167

DOI: 10.1016/j.jsb.2017.05.009

PubMed ID: 28963502

Title: Epithelial Chloride Transport by CFTR Requires TMEM16A.

PubMed ID: 28963502

DOI: 10.1038/s41598-017-10910-0

PubMed ID: 31732694

Title: TMEM16A chloride channel does not drive mucus production.

PubMed ID: 31732694

DOI: 10.26508/lsa.201900462

PubMed ID: 33026825

Title: TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells.

PubMed ID: 33026825

DOI: 10.1165/rcmb.2019-0442oc

PubMed ID: 32487539

Title: TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.

PubMed ID: 32487539

DOI: 10.1136/jmedgenet-2020-106978

Sequence Information:

  • Length: 986
  • Mass: 114078
  • Checksum: E30A02F91EF36FC2
  • Sequence:
  • MRVNEKYSTL PAEDRSVHII NICAIEDIGY LPSEGTLLNS LSVDPDAECK YGLYFRDGRR 
    KVDYILVYHH KRPSGNRTLV RRVQHSDTPS GARSVKQDHP LPGKGASLDA GSGEPPMDYH 
    EDDKRFRREE YEGNLLEAGL ELERDEDTKI HGVGFVKIHA PWNVLCREAE FLKLKMPTKK 
    MYHINETRGL LKKINSVLQK ITDPIQPKVA EHRPQTMKRL SYPFSREKQH LFDLSDKDSF 
    FDSKTRSTIV YEILKRTTCT KAKYSMGITS LLANGVYAAA YPLHDGDYNG ENVEFNDRKL 
    LYEEWARYGV FYKYQPIDLV RKYFGEKIGL YFAWLGVYTQ MLIPASIVGI IVFLYGCATM 
    DENIPSMEMC DQRHNITMCP LCDKTCSYWK MSSACATARA SHLFDNPATV FFSVFMALWA 
    ATFMEHWKRK QMRLNYRWDL TGFEEEEEAV KDHPRAEYEA RVLEKSLKKE SRNKEKRRHI 
    PEESTNKWKQ RVKTAMAGVK LTDKVKLTWR DRFPAYLTNL VSIIFMIAVT FAIVLGVIIY 
    RISMAAALAM NSSPSVRSNI RVTVTATAVI INLVVIILLD EVYGCIARWL TKIEVPKTEK 
    SFEERLIFKA FLLKFVNSYT PIFYVAFFKG RFVGRPGDYV YIFRSFRMEE CAPGGCLMEL 
    CIQLSIIMLG KQLIQNNLFE IGIPKMKKLI RYLKLKQQSP PDHEECVKRK QRYEVDYNLE 
    PFAGLTPEYM EMIIQFGFVT LFVASFPLAP LFALLNNIIE IRLDAKKFVT ELRRPVAVRA 
    KDIGIWYNIL RGIGKLAVII NAFVISFTSD FIPRLVYLYM YSKNGTMHGF VNHTLSSFNV 
    SDFQNGTAPN DPLDLGYEVQ ICRYKDYREP PWSENKYDIS KDFWAVLAAR LAFVIVFQNL 
    VMFMSDFVDW VIPDIPKDIS QQIHKEKVLM VELFMREEQD KQQLLETWME KERQKDEPPC 
    NHHNTKACPD SLGSPAPSHA YHGGVL

Genular Protein ID: 1133799003

Symbol: Q9NW72_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 594
  • Mass: 68928
  • Checksum: 3E66AE3FEA245917
  • Sequence:
  • MEMCDQRHNI TMCPLCDKTC SYWKMSSACA TARASHLFDN PATVFFSVFM ALWAATFMEH 
    WKRKQMRLNY RWDLTGFEEE EEAVKDHPRA EYEARVLEKS LKKESRNKET DKVKLTWRDR 
    FPAYLTNLVS IIFMIAVTFA IVLGVIIYRI SMAAALAMNS SPSVRSNIRV TVTATAVIIN 
    LVVIILLDEV YGCIARWLTK IEVPKTEKSF EERLIFKAFL LKFVNSYTPI FYVAFFKGRF 
    VGRPGDYVYI FRSFRMEECA PGGCLMELCI QLSIIMLGKQ LIQNNLFEIG IPKMKKLIRY 
    LKLKQQSPPD HEECVKRKQR YEVDYNLEPF AGLTPEYMEM IIQFGFVTLF VASFPLAPLF 
    ALLNNIIEIR LDAKKFVTEL RRPVAVRAKD IGIWYNILRG IGKLAVIINA FVISFTSDFI 
    PRLVYLYMYS KNGTMHGFVN HTLSSFNVSD FQNGTAPNDP LDLGYEVQIC RYKDYREPPW 
    SENKYDISKD FWAVLAARLA FVIVFQNLVM FMSDFVDWVI PDIPKDISQQ IHKEKVLMVE 
    LFMREEQDKQ QLLETWMEKE RQKDEPPCNH HNTKACPDSL GSPAPSHAYH GGVL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.