Details for: SNORA71A

Gene ID: 26777

Symbol: SNORA71A

Ensembl ID: ENSG00000225091

Description: small nucleolar RNA, H/ACA box 71A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.5648
    Cell Significance Index: 5.8500
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.2785
    Cell Significance Index: 3.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0623
    Cell Significance Index: 0.8500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.0411
    Cell Significance Index: 0.5400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.0057
    Cell Significance Index: 0.0600
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.0044
    Cell Significance Index: 0.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0045
    Cell Significance Index: -0.2100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0057
    Cell Significance Index: -0.3000
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.0099
    Cell Significance Index: -0.1200
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0156
    Cell Significance Index: -0.2200
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0262
    Cell Significance Index: -0.3100
  • Cell Name: granulocyte (CL0000094)
    Fold Change: -0.0290
    Cell Significance Index: -0.3500
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0363
    Cell Significance Index: -0.4300
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0427
    Cell Significance Index: -0.5900
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0433
    Cell Significance Index: -0.5000
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0490
    Cell Significance Index: -0.5000
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.0562
    Cell Significance Index: -0.6700
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0565
    Cell Significance Index: -0.5300
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0622
    Cell Significance Index: -0.6900
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.0652
    Cell Significance Index: -0.5900
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0681
    Cell Significance Index: -0.8800
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0685
    Cell Significance Index: -0.6500
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0739
    Cell Significance Index: -0.7500
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0805
    Cell Significance Index: -0.9900
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: -0.0896
    Cell Significance Index: -0.9100
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0924
    Cell Significance Index: -1.2500
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0966
    Cell Significance Index: -0.9000
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0989
    Cell Significance Index: -0.9300
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1045
    Cell Significance Index: -0.6600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1079
    Cell Significance Index: -1.3600
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.1092
    Cell Significance Index: -1.1900
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.1094
    Cell Significance Index: -1.3700
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.1176
    Cell Significance Index: -1.2500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1185
    Cell Significance Index: -1.3900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1228
    Cell Significance Index: -1.4600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1239
    Cell Significance Index: -1.3500
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1250
    Cell Significance Index: -1.3400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1281
    Cell Significance Index: -1.5500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1518
    Cell Significance Index: -1.4400
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.1693
    Cell Significance Index: -1.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORA71A is a 71-nucleotide-long snoRNA, which is a type of non-coding RNA that guides the modification of rRNA and other non-coding RNAs in the nucleolus. snoRNAs are known to play critical roles in RNA processing, including the formation and maturation of ribosomes. SNORA71A, in particular, has been identified as a member of the H/ACA class of snoRNAs, which are characterized by the presence of specific H/ACA boxes. These boxes are involved in the recognition and binding of snoRNAs to target rRNA sequences, facilitating the modification of these RNAs. **Pathways and Functions:** The expression of SNORA71A in various cell types suggests its involvement in multiple cellular processes, including RNA processing and immune response regulation. In the context of RNA processing, SNORA71A is likely to play a role in the modification of rRNA, which is essential for ribosome biogenesis and function. Additionally, the snoRNA may influence the expression of other non-coding RNAs, such as microRNAs and long non-coding RNAs, which are involved in various cellular processes, including gene regulation and immune response. The expression of SNORA71A in immune cells, such as B cells and macrophages, raises the possibility that this snoRNA may play a role in immune response regulation. Immune cells rely on precise regulation of gene expression to respond to pathogens and maintain tissue homeostasis. The involvement of SNORA71A in immune cell function suggests that this snoRNA may contribute to the regulation of immune responses, potentially by influencing the expression of genes involved in inflammation, cytokine production, or antigen presentation. **Clinical Significance:** The identification of SNORA71A as a significant player in RNA processing and immune response regulation has important implications for our understanding of human diseases. Dysregulation of RNA processing and immune response has been implicated in various diseases, including cancer, autoimmune disorders, and infectious diseases. Further research into the functions of SNORA71A is warranted, given its potential role in these diseases. For example, mutations or alterations in the expression of SNORA71A may contribute to the development of autoimmune disorders, such as rheumatoid arthritis or lupus, by disrupting the normal regulation of immune responses. Additionally, the involvement of SNORA71A in RNA processing may also have implications for the development of cancer, as changes in rRNA modification can affect ribosome biogenesis and function, potentially contributing to tumorigenesis. In conclusion, the study of SNORA71A provides valuable insights into the complex regulation of RNA processing and immune response. Further research into the functions of this snoRNA is necessary to fully understand its role in human disease and to develop novel therapeutic strategies for the treatment of diseases associated with dysregulated RNA processing and immune response.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.