Details for: BRSK2
Associated with
Other Information
Genular Protein ID: 4152579637
Symbol: BRSK2_HUMAN
Name: Serine/threonine-protein kinase BRSK2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16630837
Title: SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.
PubMed ID: 16630837
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 11124703
Title: Characterization of 16 novel human genes showing high similarity to yeast sequences.
PubMed ID: 11124703
DOI: 10.1002/1097-0061(200101)18:1<69::aid-yea647>3.0.co;2-h
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9929968
Title: Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta.
PubMed ID: 9929968
PubMed ID: 14976552
Title: LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.
PubMed ID: 14976552
PubMed ID: 16870137
Title: BRSK2 is activated by cyclic AMP-dependent protein kinase A through phosphorylation at Thr260.
PubMed ID: 16870137
PubMed ID: 18339622
Title: Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.
PubMed ID: 18339622
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19958286
Title: Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.
PubMed ID: 19958286
DOI: 10.1042/bj20091372
PubMed ID: 20026642
Title: Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.
PubMed ID: 20026642
DOI: 10.1242/jcs.058230
PubMed ID: 22609399
Title: Jab1 interacts with brain-specific kinase 2 (BRSK2) and promotes its degradation in the ubiquitin-proteasome pathway.
PubMed ID: 22609399
PubMed ID: 22713462
Title: BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis.
PubMed ID: 22713462
PubMed ID: 22669945
Title: Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic beta-Cells.
PubMed ID: 22669945
PubMed ID: 22798068
Title: Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic beta-cells.
PubMed ID: 22798068
PubMed ID: 21985311
Title: Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.
PubMed ID: 21985311
PubMed ID: 23029325
Title: APC/C(Cdh1) targets brain-specific kinase 2 (BRSK2) for degradation via the ubiquitin-proteasome pathway.
PubMed ID: 23029325
Sequence Information:
- Length: 736
- Mass: 81633
- Checksum: D9EBA511149449E6
- Sequence:
MTSTGKDGGA QHAQYVGPYR LEKTLGKGQT GLVKLGVHCV TCQKVAIKIV NREKLSESVL MKVEREIAIL KLIEHPHVLK LHDVYENKKY LYLVLEHVSG GELFDYLVKK GRLTPKEARK FFRQIISALD FCHSHSICHR DLKPENLLLD EKNNIRIADF GMASLQVGDS LLETSCGSPH YACPEVIRGE KYDGRKADVW SCGVILFALL VGALPFDDDN LRQLLEKVKR GVFHMPHFIP PDCQSLLRGM IEVDAARRLT LEHIQKHIWY IGGKNEPEPE QPIPRKVQIR SLPSLEDIDP DVLDSMHSLG CFRDRNKLLQ DLLSEEENQE KMIYFLLLDR KERYPSQEDE DLPPRNEIDP PRKRVDSPML NRHGKRRPER KSMEVLSVTD GGSPVPARRA IEMAQHGQRS RSISGASSGL STSPLSSPRV TPHPSPRGSP LPTPKGTPVH TPKESPAGTP NPTPPSSPSV GGVPWRARLN SIKNSFLGSP RFHRRKLQVP TPEEMSNLTP ESSPELAKKS WFGNFISLEK EEQIFVVIKD KPLSSIKADI VHAFLSIPSL SHSVISQTSF RAEYKATGGP AVFQKPVKFQ VDITYTEGGE AQKENGIYSV TFTLLSGPSR RFKRVVETIQ AQLLSTHDPP AAQHLSDTTN CMEMMTGRLS KCGSPLSNFF DVIKQLFSDE KNGQAAQAPS TPAKRSAHGP LGDSAAAGPG PGGDAEYPTG KDTAKMGPPT ARREQP
Genular Protein ID: 3449828993
Symbol: A0A140VJF6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 668
- Mass: 74741
- Checksum: 2E3BE2942B8BD79B
- Sequence:
MTSTGKDGGA QHAQYVGPYR LEKTLGKGQT GLVKLGVHCV TCQKVAIKIV NREKLSESVL MKVEREIAIL KLIEHPHVLK LHDVYENKKY LYLVLEHVSG GELFDYLVKK GRLTPKEARK FFRQIISALD FCHSHSICHR DLKPENLLLD EKNNIRIADF GMASLQVGDS LLETSCGSPH YACPEVIRGE KYDGRKADVW SCGVILFALL VGALPFDDDN LRQLLEKVKR GVFHMPHFIP PDCQSLLRGM IEVDAARRLT LEHIQKHIWY IGGKNEPEPE QPIPRKVQIR SLPSLEDIDP DVLDSMHSLG CFRDRNKLLQ DLLSEEENQE KMIYFLLLDR KERYPSQEDE DLPPRNEIDP PRKRVDSPML NRHGKRRPER KSMEVLSVTD GGSPVPARRA IEMAQHGQRS RSISGASSGL STSPLSSPRV TPHPSPRGSP LPTPKGTPVH TPKESPAGTP NPTPPSSPSV GGVPWRARLN SIKNSFLGSP RFHRRKLQVP TPEEMSNLTP ESSPELAKKS WFGNFISLEK EEQIFVVIKD KPLSSIKADI VHAFLSIPSL SHSVISQTSF RAEYKATGGP AVFQKPVKFQ VDITYTEGGE AQKENGIYSV TFTLLSGPSR RFKRVVETIQ AQLLSTHDPP AAQHLSDTTN CMEMMTGRLS KCGIIPKS
Genular Protein ID: 1557957110
Symbol: B4DLY3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 440
- Mass: 48800
- Checksum: 8F4190A75EFF3889
- Sequence:
MPHFIPPDCQ SLLRGMIEVD AARRLTLEHI QKHIWYIGGK NEPEPEQPIP RKVQIRSLPS LEDIDPDVLD SMHSLGCFRD RNKLLQDLLS EEENQEKMIY FLLLDRKERY PSQEDEDLPP RNEIDPPRKR VDSPMLNRHG KRRPERKSME VLSVTDGGSP VPARRAIEMA QHGQRSRSIS GASSGLSTSP LSSPRVTPHP SPRGSPLPTP KGTPVHTPKE SPAGTPNPTP PSSPSVGGVP WRARLNSIKN SFLGSPRFHR RKLQVPTPEE MSNLTPESSP ELAKKSWFGN FISLEKEEQI FVVIKDKPLS SIKADIVHAF LSIPSLSHSV ISQTSFRAEY KATGGPAVFQ KPVKFQVDIT YTEGGEAQKE NGIYSVTFTL LSGPSRRFKR VVETIQAQLL STHDPPAAQH LSEPPPPAPG LSWGAGLKGQ KVATSYESSL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.