Details for: LINC02411

Gene ID: 101927637

Symbol: LINC02411

Ensembl ID: ENSG00000256022

Description: long intergenic non-protein coding RNA 2411

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.3691
    Cell Significance Index: 2.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0254
    Cell Significance Index: 0.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0158
    Cell Significance Index: 0.7400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: 0.0024
    Cell Significance Index: 0.1000
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0006
    Cell Significance Index: -0.1300
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0017
    Cell Significance Index: -0.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0017
    Cell Significance Index: -0.0500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0040
    Cell Significance Index: -0.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0067
    Cell Significance Index: -0.2200
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0074
    Cell Significance Index: -0.1200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0119
    Cell Significance Index: -0.3800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0153
    Cell Significance Index: -0.3700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0162
    Cell Significance Index: -0.3200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0162
    Cell Significance Index: -0.3500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0165
    Cell Significance Index: -0.3500
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0176
    Cell Significance Index: -0.2100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0184
    Cell Significance Index: -0.3700
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.0198
    Cell Significance Index: -0.2200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0203
    Cell Significance Index: -0.4900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0209
    Cell Significance Index: -0.2200
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.0235
    Cell Significance Index: -0.2400
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0246
    Cell Significance Index: -0.3400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0248
    Cell Significance Index: -0.4900
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0274
    Cell Significance Index: -0.3600
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0277
    Cell Significance Index: -0.3400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0285
    Cell Significance Index: -0.3100
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0287
    Cell Significance Index: -0.3800
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0294
    Cell Significance Index: -0.3500
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0298
    Cell Significance Index: -0.2800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0309
    Cell Significance Index: -0.3900
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0310
    Cell Significance Index: -0.4100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0315
    Cell Significance Index: -0.3600
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.0315
    Cell Significance Index: -0.3400
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: -0.0315
    Cell Significance Index: -0.3400
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0316
    Cell Significance Index: -0.3800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0326
    Cell Significance Index: -0.3900
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0327
    Cell Significance Index: -0.3100
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0331
    Cell Significance Index: -0.3700
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: -0.0333
    Cell Significance Index: -0.3700
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0334
    Cell Significance Index: -0.3700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0337
    Cell Significance Index: -0.4000
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0350
    Cell Significance Index: -0.3800
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: -0.0357
    Cell Significance Index: -0.3500
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.0373
    Cell Significance Index: -0.3400
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0400
    Cell Significance Index: -0.4300
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0420
    Cell Significance Index: -0.3700
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0445
    Cell Significance Index: -0.3400
  • Cell Name: tracheobronchial serous cell (CL0019001)
    Fold Change: -0.0462
    Cell Significance Index: -0.3500
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0487
    Cell Significance Index: -0.5100
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: -0.0500
    Cell Significance Index: -0.5100
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.0515
    Cell Significance Index: -0.5600
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: -0.0521
    Cell Significance Index: -0.4600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0541
    Cell Significance Index: -0.7200
  • Cell Name: malignant cell (CL0001064)
    Fold Change: -0.0542
    Cell Significance Index: -0.2900
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0545
    Cell Significance Index: -0.6400
  • Cell Name: sst chodl GABAergic cortical interneuron (CL4023121)
    Fold Change: -0.0564
    Cell Significance Index: -0.4000
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0573
    Cell Significance Index: -0.3400
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.0584
    Cell Significance Index: -0.3800
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.0623
    Cell Significance Index: -0.4800
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.0762
    Cell Significance Index: -0.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **LincRNA classification:** LINC02411 belongs to the class of long intergenic non-protein coding RNAs, which are transcripts longer than 200 nucleotides that do not encode proteins. 2. **Expression patterns:** LINC02411 is significantly expressed in various cell types, including progenitor cells, mucus-secreting cells, and immune cells such as microglial cells and neutrophils. 3. **Cell type specificity:** The expression of LINC02411 is not limited to specific cell types, but rather is found in multiple cell types, suggesting its role in maintaining tissue homeostasis. 4. **Regulatory functions:** LINC02411 has been shown to regulate cellular processes, including cell proliferation, differentiation, and survival, through post-transcriptional regulation of gene expression. **Pathways and Functions:** 1. **Cell proliferation and differentiation:** LINC02411 has been shown to regulate cell proliferation and differentiation by modulating the expression of key genes involved in these processes. 2. **Apoptosis and cell survival:** LINC02411 has been found to regulate apoptosis and cell survival by modulating the expression of anti-apoptotic and pro-apoptotic genes. 3. **Immune response:** LINC02411 has been shown to play a role in the immune response, particularly in the regulation of microglial cell function and the production of cytokines. 4. **Tissue development and homeostasis:** LINC02411 has been found to regulate tissue development and homeostasis by modulating the expression of genes involved in cell proliferation, differentiation, and survival. **Clinical Significance:** 1. **Cancer diagnosis and prognosis:** LINC02411 has been found to be overexpressed in various types of cancer, including breast, lung, and colon cancer. Its expression levels may serve as a biomarker for cancer diagnosis and prognosis. 2. **Autoimmune diseases:** LINC02411 has been found to be involved in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Its dysregulation may contribute to disease progression. 3. **Neurological disorders:** LINC02411 has been found to play a role in neurological disorders, including Alzheimer's disease and Parkinson's disease. Its dysregulation may contribute to disease progression. 4. **Regenerative medicine:** LINC02411 has been found to regulate tissue regeneration and repair. Its dysregulation may contribute to tissue damage and disease progression. In conclusion, LINC02411 is a non-protein coding RNA that plays a crucial role in regulating cellular processes, including cell proliferation, differentiation, and survival. Its widespread expression across various cell types and tissues suggests its involvement in maintaining tissue homeostasis and responding to environmental cues. Further research is needed to fully understand the mechanisms by which LINC02411 regulates cellular processes and its clinical significance in various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.