Details for: RCN2
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 92.07rCSI 72.77%PRS 30.69
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CSI 70.11rCSI 67.49%PRS 42.65
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CSI 54.48rCSI 65.4%PRS 40.3
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CSI 52.47rCSI 60.59%PRS 36.88
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CSI 43.9rCSI 59.82%PRS 36.01
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CSI 42.6rCSI 54.67%PRS 40.16
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CSI 41.84rCSI 58.13%PRS 41.67
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CSI 29.37rCSI 41.91%PRS 44.76
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CSI 28.07rCSI 43.37%PRS 40.08
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CSI 24.86rCSI 20.61%PRS 40.61
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CSI 24.86rCSI 79.76%PRS 49.89
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CSI 24.12rCSI 38.47%PRS 36.46
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CSI 19.98rCSI 17.57%PRS 32.02
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CSI 19.72rCSI 24.39%PRS 38.19
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CSI 19.54rCSI 32.8%PRS 27.55
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CSI 18.59rCSI 32.79%PRS 50.57
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CSI 17.64rCSI 16.31%PRS 62.31
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CSI 17.12rCSI 17.89%PRS 41.72
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CSI 14.81rCSI 11.13%PRS 45.28
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CSI 13.35rCSI 12.87%PRS 33.28
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CSI 13.24rCSI 37.64%PRS 42.23
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CSI 12.58rCSI 31.94%PRS 38.57
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CSI 12.34rCSI 10.34%PRS 47.16
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CSI 12.16rCSI 19.92%PRS 33.48
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CSI 11.92rCSI 18.17%PRS 38.94
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CSI 11.55rCSI 9.56%PRS 43.04
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CSI 11.42rCSI 13.39%PRS 57.22
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CSI 11.29rCSI 14.37%PRS 47.18
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CSI 10.9rCSI 17.58%PRS 51.02
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CSI 10.58rCSI 15.63%PRS 59.22
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CSI 10.34rCSI 39.02%PRS 36.24
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CSI 9.12rCSI 26.43%PRS 34.23
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CSI 9.07rCSI 8.05%PRS 41.3
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CSI 8.98rCSI 26.66%PRS 53.72
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CSI 8.89rCSI 56.95%PRS 48.78
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CSI 8.73rCSI 18.11%PRS 40.21
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CSI 8.46rCSI 9.52%PRS 58.02
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CSI 8.36rCSI 24.19%PRS 44.62
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CSI 8.09rCSI 5.39%PRS 68.03
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CSI 8.06rCSI 6.55%PRS 43
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CSI 7.95rCSI 6.42%PRS 42.6
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CSI 7.74rCSI 6.79%PRS 46.88
-
CSI 7.73rCSI 22.81%PRS 46.08
-
CSI 7.71rCSI 24.99%PRS 45.22
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CSI 7.52rCSI 11.94%PRS 52.22
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CSI 7.25rCSI 11.52%PRS 35.82
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CSI 7.16rCSI 5.3%PRS 36.29
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CSI 7.06rCSI 7.04%PRS 36.67
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CSI 7.05rCSI 9.77%PRS 47.34
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CSI 7.05rCSI 11.26%PRS 45.64
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CSI 6.91rCSI 4.08%PRS 56.53
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CSI 6.87rCSI 39.96%PRS 53
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CSI 6.75rCSI 15.72%PRS 60.23
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CSI 6.48rCSI 20.26%PRS 28.68
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CSI 6.46rCSI 7.72%PRS 27.54
-
CSI 6.41rCSI 9.85%PRS 44.73
-
CSI 6.14rCSI 16.88%PRS 57.46
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CSI 6.11rCSI 10.58%PRS 33.43
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CSI 6.01rCSI 4.18%PRS 50.29
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CSI 5.96rCSI 8.15%PRS 46.69
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CSI 5.96rCSI 5.86%PRS 44.26
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CSI 5.95rCSI 5.88%PRS 76.54
-
CSI 5.92rCSI 6.18%PRS 42.75
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CSI 5.89rCSI 15.54%PRS 49.37
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CSI 5.77rCSI 20.98%PRS 75.9
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CSI 5.51rCSI 5.61%PRS 54.88
-
CSI 5.44rCSI 4.14%PRS 53.12
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CSI 5.4rCSI 12.81%PRS 47.92
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CSI 5.33rCSI 78.74%PRS 64.65
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CSI 5.28rCSI 4.99%PRS 43.19
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CSI 5.21rCSI 4.1%PRS 48.36
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CSI 5.17rCSI 11.38%PRS 45.9
-
CSI 5.1rCSI 6.4%PRS 51.49
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CSI 5.1rCSI 3.66%PRS 54.56
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CSI 5.04rCSI 13.43%PRS 35.04
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CSI 5.04rCSI 3.78%PRS 74.7
-
CSI 5.02rCSI 22.31%PRS 40.75
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CSI 5rCSI 9.92%PRS 41.75
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CSI 4.9rCSI 53.65%PRS 58.92
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CSI 4.86rCSI 8.58%PRS 26.62
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CSI 4.62rCSI 13.25%PRS 59.23
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CSI 4.57rCSI 3.04%PRS 46.08
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CSI 4.56rCSI 6.7%PRS 38.54
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CSI 4.46rCSI 9.96%PRS 48.21
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CSI 4.45rCSI 3.56%PRS 63.44
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CSI 4.33rCSI 5.01%PRS 32.88
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CSI 4.3rCSI 3%PRS 54.66
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CSI 4.29rCSI 3.24%PRS 53.97
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CSI 4.23rCSI 5.66%PRS 43.68
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CSI 4.16rCSI 14.24%PRS 34.66
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CSI 4.15rCSI 5.67%PRS 38.97
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CSI 4.14rCSI 8.4%PRS 25.88
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CSI 4.13rCSI 15.48%PRS 35.81
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CSI 4.12rCSI 3.72%PRS 38.82
-
CSI 4.1rCSI 8.73%PRS 46.91
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CSI 4.06rCSI 6.57%PRS 40.78
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CSI 4.06rCSI 3.04%PRS 56.65
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CSI 4.04rCSI 4.15%PRS 59.48
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CSI 3.76rCSI 6.05%PRS 29.57
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CSI 3.74rCSI 2.78%PRS 54.98
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CSI 0.1rCSI 2.5%PRS 64.8%
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CSI 0.1rCSI 3.2%PRS 69.4%
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CSI 0.2rCSI 4.8%PRS 77.5%
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CSI 0.2rCSI 3.3%PRS 77.0%
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CSI 0.2rCSI 1.2%PRS 54.3%
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CSI 0.2rCSI 2.0%PRS 37.2%
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CSI 0.3rCSI 2.7%PRS 62.9%
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CSI 0.3rCSI 1.6%PRS 77.9%
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CSI 0.3rCSI 4.7%PRS 68.1%
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CSI 0.4rCSI 5.3%PRS 67.7%
-
CSI 0.4rCSI 6.0%PRS 78.7%
-
CSI 0.4rCSI 1.2%PRS 35.6%
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CSI 0.4rCSI 4.1%PRS 61.0%
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CSI 0.4rCSI 3.1%PRS 66.7%
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CSI 0.5rCSI 3.4%PRS 62.3%
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CSI 0.5rCSI 3.8%PRS 74.1%
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CSI 0.5rCSI 1.6%PRS 31.7%
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CSI 0.5rCSI 2.2%PRS 58.7%
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CSI 0.5rCSI 2.4%PRS 78.0%
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CSI 0.5rCSI 1.2%PRS 39.4%
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CSI 0.5rCSI 2.0%PRS 62.2%
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CSI 0.5rCSI 3.6%PRS 40.5%
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CSI 0.5rCSI 1.6%PRS 72.9%
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CSI 0.6rCSI 1.5%PRS 80.4%
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CSI 0.6rCSI 4.0%PRS 30.9%
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CSI 0.6rCSI 2.0%PRS 51.9%
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CSI 0.6rCSI 1.5%PRS 32.3%
-
CSI 0.6rCSI 1.2%PRS 65.4%
-
CSI 0.7rCSI 1.3%PRS 51.8%
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CSI 0.8rCSI 4.0%PRS 57.1%
-
CSI 0.8rCSI 10.5%PRS 75.6%
-
CSI 0.8rCSI 5.9%PRS 68.6%
-
CSI 0.9rCSI 3.3%PRS 60.8%
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CSI 0.9rCSI 2.1%PRS 26.8%
-
CSI 0.9rCSI 2.5%PRS 56.8%
-
CSI 0.9rCSI 2.9%PRS 74.2%
-
CSI 0.9rCSI 2.0%PRS 61.8%
-
CSI 0.9rCSI 1.7%PRS 40.6%
-
CSI 1.0rCSI 9.3%PRS 82.9%
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CSI 1.0rCSI 3.6%PRS 78.5%
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CSI 1.1rCSI 2.7%PRS 33.3%
-
CSI 1.1rCSI 7.5%PRS 60.7%
-
CSI 1.1rCSI 4.4%PRS 45.1%
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CSI 1.1rCSI 2.5%PRS 51.9%
-
CSI 1.2rCSI 2.5%PRS 57.1%
-
CSI 1.2rCSI 2.8%PRS 59.6%
-
CSI 1.2rCSI 2.8%PRS 54.5%
-
CSI 1.2rCSI 1.0%PRS 45.7%
-
CSI 1.2rCSI 2.7%PRS 40.9%
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CSI 1.2rCSI 1.8%PRS 43.9%
-
CSI 1.2rCSI 2.9%PRS 52.4%
-
CSI 1.2rCSI 6.1%PRS 52.8%
-
CSI 1.2rCSI 4.7%PRS 28.5%
-
CSI 1.3rCSI 3.3%PRS 45.1%
-
CSI 1.3rCSI 1.2%PRS 66.0%
-
CSI 1.3rCSI 4.5%PRS 57.8%
-
CSI 1.3rCSI 3.4%PRS 55.4%
-
CSI 1.3rCSI 1.6%PRS 55.3%
-
CSI 1.3rCSI 2.6%PRS 71.9%
-
CSI 1.3rCSI 2.0%PRS 46.6%
-
CSI 1.3rCSI 4.8%PRS 61.0%
-
CSI 1.4rCSI 7.7%PRS 52.9%
-
CSI 1.4rCSI 3.3%PRS 52.8%
-
CSI 1.4rCSI 1.7%PRS 62.3%
-
CSI 1.4rCSI 3.7%PRS 38.6%
-
CSI 1.4rCSI 2.1%PRS 34.1%
-
CSI 1.4rCSI 12.4%PRS 80.8%
-
CSI 1.5rCSI 6.9%PRS 67.9%
-
CSI 1.5rCSI 4.6%PRS 30.8%
-
CSI 1.5rCSI 2.3%PRS 42.6%
-
CSI 1.5rCSI 1.6%PRS 57.2%
-
CSI 1.5rCSI 7.8%PRS 66.1%
-
CSI 1.6rCSI 1.6%PRS 44.6%
-
CSI 1.6rCSI 4.2%PRS 64.8%
-
CSI 1.6rCSI 2.3%PRS 55.7%
-
CSI 1.6rCSI 2.2%PRS 54.8%
-
CSI 1.6rCSI 2.9%PRS 35.9%
-
CSI 1.6rCSI 3.1%PRS 62.1%
-
CSI 1.7rCSI 18.1%PRS 91.3%
-
CSI 1.7rCSI 2.6%PRS 50.9%
-
CSI 1.7rCSI 8.4%PRS 53.5%
-
CSI 1.8rCSI 42.2%PRS 27.9%
-
CSI 1.8rCSI 2.6%PRS 46.8%
-
CSI 1.8rCSI 4.5%PRS 50.2%
-
CSI 1.8rCSI 3.6%PRS 37.2%
-
CSI 1.8rCSI 42.9%PRS 27.0%
-
CSI 1.8rCSI 3.4%PRS 76.1%
-
CSI 1.8rCSI 1.7%PRS 43.0%
-
CSI 1.8rCSI 2.2%PRS 61.0%
-
CSI 1.8rCSI 2.1%PRS 64.9%
-
CSI 1.9rCSI 2.8%PRS 59.3%
-
CSI 1.9rCSI 2.3%PRS 49.6%
-
CSI 1.9rCSI 7.6%PRS 63.7%
-
CSI 1.9rCSI 2.6%PRS 52.3%
-
CSI 1.9rCSI 3.1%PRS 33.5%
-
CSI 1.9rCSI 1.7%PRS 50.9%
-
CSI 2.0rCSI 4.8%PRS 40.3%
-
CSI 2.0rCSI 4.5%PRS 47.8%
-
CSI 2.0rCSI 8.9%PRS 36.3%
-
CSI 2.0rCSI 3.6%PRS 35.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 852075058
Symbol: RCN2_HUMAN
Name: Reticulocalbin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8034671
Title: The endoplasmic reticulum calcium-binding protein of 55 kDa is a novel EF-hand protein retained in the endoplasmic reticulum by a carboxyl-terminal His-Asp-Glu-Leu motif.
PubMed ID: 8034671
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 317
- Mass: 36876
- Checksum: E7C0A4211DBF04AB
- Sequence:
MRLGPRTAAL GLLLLCAAAA GAGKAEELHY PLGERRSDYD REALLGVQED VDEYVKLGHE EQQKRLQAII KKIDLDSDGF LTESELSSWI QMSFKHYAMQ EAKQQFVEYD KNSDDTVTWD EYNIQMYDRV IDFDENTALD DAEEESFRKL HLKDKKRFEK ANQDSGPGLS LEEFIAFEHP EEVDYMTEFV IQEALEEHDK NGDGFVSLEE FLGDYRWDPT ANEDPEWILV EKDRFVNDYD KDNDGRLDPQ ELLPWVVPNN QGIAQEEALH LIDEMDLNGD KKLSEEEILE NPDLFLTSEA TDYGRQLHDD YFYHDEL