Details for: TRGJP

Gene ID: 6970

Symbol: TRGJP

Ensembl ID: ENSG00000211691

Description: T cell receptor gamma joining P

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 2.0844
    Cell Significance Index: 50.4900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.9677
    Cell Significance Index: 10.0100
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.6151
    Cell Significance Index: 8.0300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.4480
    Cell Significance Index: 6.5300
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.4309
    Cell Significance Index: 5.6600
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.1003
    Cell Significance Index: 1.6300
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.0505
    Cell Significance Index: 1.0300
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.0176
    Cell Significance Index: 0.0900
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: -0.0009
    Cell Significance Index: -0.0100
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0034
    Cell Significance Index: -0.0400
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0056
    Cell Significance Index: -0.0500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0061
    Cell Significance Index: -0.1200
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0077
    Cell Significance Index: -0.1100
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0136
    Cell Significance Index: -0.2000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0141
    Cell Significance Index: -0.1700
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0147
    Cell Significance Index: -0.2000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0167
    Cell Significance Index: -0.2100
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0168
    Cell Significance Index: -0.1700
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0177
    Cell Significance Index: -0.2000
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0192
    Cell Significance Index: -0.3300
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0227
    Cell Significance Index: -0.2100
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0237
    Cell Significance Index: -0.2800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0241
    Cell Significance Index: -0.4000
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0244
    Cell Significance Index: -0.2700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0256
    Cell Significance Index: -0.3400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0268
    Cell Significance Index: -0.3500
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: -0.0276
    Cell Significance Index: -0.3500
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: -0.0284
    Cell Significance Index: -0.2700
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0292
    Cell Significance Index: -0.3100
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0294
    Cell Significance Index: -0.3400
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0299
    Cell Significance Index: -0.2800
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0328
    Cell Significance Index: -0.4200
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.0339
    Cell Significance Index: -0.3900
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.0382
    Cell Significance Index: -0.3900
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: -0.0382
    Cell Significance Index: -0.4100
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0390
    Cell Significance Index: -0.3700
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: -0.0398
    Cell Significance Index: -0.4700
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: -0.0413
    Cell Significance Index: -0.4800
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0414
    Cell Significance Index: -0.4700
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: -0.0415
    Cell Significance Index: -0.4300
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.0421
    Cell Significance Index: -0.3800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0421
    Cell Significance Index: -0.3400
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0434
    Cell Significance Index: -0.4000
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.0434
    Cell Significance Index: -0.4200
  • Cell Name: club cell (CL0000158)
    Fold Change: -0.0436
    Cell Significance Index: -0.4800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0443
    Cell Significance Index: -0.3900
  • Cell Name: immature B cell (CL0000816)
    Fold Change: -0.0449
    Cell Significance Index: -0.4300
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.0450
    Cell Significance Index: -0.4400
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0458
    Cell Significance Index: -0.3500
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.0469
    Cell Significance Index: -0.4400
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0469
    Cell Significance Index: -0.4100
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: -0.0485
    Cell Significance Index: -0.5100
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.0491
    Cell Significance Index: -0.4200
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.0503
    Cell Significance Index: -0.4300
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -0.0519
    Cell Significance Index: -0.5500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.0567
    Cell Significance Index: -0.3500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0574
    Cell Significance Index: -1.0600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0601
    Cell Significance Index: -1.0200
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.0730
    Cell Significance Index: -0.6500
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0731
    Cell Significance Index: -0.7300
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: -0.0813
    Cell Significance Index: -0.6500
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0818
    Cell Significance Index: -0.8300
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: -0.0847
    Cell Significance Index: -0.7000
  • Cell Name: obsolete animal cell (CL0000548)
    Fold Change: -0.0932
    Cell Significance Index: -0.9500
  • Cell Name: platelet (CL0000233)
    Fold Change: -0.1011
    Cell Significance Index: -1.0400
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.1015
    Cell Significance Index: -0.7900
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: -0.1224
    Cell Significance Index: -1.0100
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.1816
    Cell Significance Index: -0.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression in diverse cell types:** TRGJP is significantly expressed in a wide range of cell types, including plasma cells, T cells, goblet cells, innate lymphoid cells, B cells, abnormal cells, neoplastic cells, absorptive cells, alpha-beta T cells, and mature NK T cells. This widespread expression suggests a multifaceted role in the immune system. 2. **Ensembl ID:** TRGJP is identified by the Ensembl ID ENSG00000211691, which provides a unique identifier for the gene. 3. **Cellular localization:** The exact cellular localization of TRGJP is not explicitly mentioned, but its expression in various cell types implies a dynamic and adaptable role in immune responses. **Pathways and Functions:** 1. **Immunological signaling:** TRGJP is likely involved in immunological signaling pathways, facilitating communication between immune cells and influencing the activation, proliferation, and differentiation of T cells and other immune cells. 2. **Cell adhesion and migration:** The gene may also play a role in cell adhesion and migration, enabling immune cells to migrate to sites of inflammation and infection. 3. **Apoptosis and cell survival:** TRGJP could be involved in regulating apoptosis (programmed cell death) and cell survival, impacting the balance between immune cell activation and elimination. 4. **Antigen presentation:** The gene may contribute to the process of antigen presentation, where immune cells recognize and process antigens to trigger an immune response. **Clinical Significance:** 1. **Cancer association:** TRGJP's expression in neoplastic cells suggests a potential link to cancer development and progression. Further research is needed to understand the role of TRGJP in tumorigenesis. 2. **Autoimmune diseases:** The gene's involvement in various immune cell types implies a possible connection to autoimmune diseases, where the immune system mistakenly attacks healthy tissues. 3. **Infectious diseases:** TRGJP's expression in innate lymphoid cells and other immune cells suggests a potential role in the host defense against infections. 4. **Immunotherapy:** Understanding TRGJP's functions and pathways could provide insights into the development of novel immunotherapies targeting specific immune cell types or signaling pathways. In conclusion, the TRGJP gene is a complex and multifaceted entity, with significant implications for our understanding of the immune system and its role in human health and disease. Further research is necessary to unravel the mysteries of TRGJP and its potential applications in the field of immunology.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.