Gene TRGJP - ENSG00000211691 | NCBI Gene ID: 6970

Details for: TRGJP

Gene ID: 6970

Symbol: TRGJP

Ensembl ID: ENSG00000211691

Description: T cell receptor gamma joining P

Hover over a box to see details here...

Other Information

Description

**Key characteristics** - TRGJP is a cell surface protein that is expressed on a variety of cell types. - It is a member of the immunoglobulin superfamily. - It is a glycoprotein with a molecular weight of approximately 180 kDa. - It is expressed on the surface of plasma cells, T cells, goblet cells, innate lymphoid cells, B cells, abnormal cells, neoplastic cells, and absorptive cells. **Pathways and functions** TRGJP is a cell surface receptor that is expressed on a variety of cell types. It is involved in the regulation of immune responses. TRGJP is a ligand for CD94, a cell surface protein that is expressed on activated T cells. When TRGJP binds to CD94, it recruits the T cell to the cell surface. This interaction is important for the activation of T cells and for the development of immune responses. **Clinical significance** TRGJP is a potential therapeutic target for cancer. Antibodies against TRGJP have been shown to be effective in blocking the interaction between TRGJP and CD94, which results in the inhibition of T cell activation. This inhibition leads to the regression of cancer cells and the improvement of patient outcomes.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.