Details for: DAPK2

Gene ID: 23604

Symbol: DAPK2

Ensembl ID: ENSG00000035664

Description: death associated protein kinase 2

Associated with

Other Information

Genular Protein ID: 2779257765

Symbol: DAPK2_HUMAN

Name: Death-associated protein kinase 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10376525

Title: Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity.

PubMed ID: 10376525

DOI: 10.1038/sj.onc.1202701

PubMed ID: 10629061

Title: Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis.

PubMed ID: 10629061

DOI: 10.1128/mcb.20.3.1044-1054.2000

PubMed ID: 21408167

Title: New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform.

PubMed ID: 21408167

DOI: 10.1371/journal.pone.0017344

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11230133

Title: Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding.

PubMed ID: 11230133

DOI: 10.1093/emboj/20.5.1099

PubMed ID: 12445458

Title: The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases.

PubMed ID: 12445458

DOI: 10.1016/s1570-9639(02)00443-0

PubMed ID: 11980920

Title: DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death.

PubMed ID: 11980920

DOI: 10.1083/jcb.200109094

PubMed ID: 16756490

Title: The death-associated protein kinases: structure, function, and beyond.

PubMed ID: 16756490

DOI: 10.1146/annurev.biochem.75.103004.142615

PubMed ID: 17347302

Title: The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells.

PubMed ID: 17347302

DOI: 10.1189/jlb.0606400

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18957423

Title: Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells.

PubMed ID: 18957423

DOI: 10.1074/jbc.m805612200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24163421

Title: DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants.

PubMed ID: 24163421

DOI: 10.1189/jlb.0813462

PubMed ID: 26047703

Title: Suppression of death-associated protein kinase 2 by interaction with 14-3-3 proteins.

PubMed ID: 26047703

DOI: 10.1016/j.bbrc.2015.05.105

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 370
  • Mass: 42898
  • Checksum: 035E914BBCD881A2
  • Sequence:
  • MFQASMRSPN MEPFKQQKVE DFYDIGEELG SGQFAIVKKC REKSTGLEYA AKFIKKRQSR 
    ASRRGVSREE IEREVSILRQ VLHHNVITLH DVYENRTDVV LILELVSGGE LFDFLAQKES 
    LSEEEATSFI KQILDGVNYL HTKKIAHFDL KPENIMLLDK NIPIPHIKLI DFGLAHEIED 
    GVEFKNIFGT PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGD TKQETLANIT 
    AVSYDFDEEF FSQTSELAKD FIRKLLVKET RKRLTIQEAL RHPWITPVDN QQAMVRRESV 
    VNLENFRKQY VRRRWKLSFS IVSLCNHLTR SLMKKVHLRP DEDLRNCESD TEEDIARRKA 
    LHPRRRSSTS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.