Details for: SSB

Gene ID: 6741

Symbol: SSB

Ensembl ID: ENSG00000138385

Description: small RNA binding exonuclease protection factor La

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 407.2770
    Cell Significance Index: -63.3500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 230.2445
    Cell Significance Index: -58.4000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 198.5932
    Cell Significance Index: -81.8100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 173.7260
    Cell Significance Index: -82.0200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 151.5401
    Cell Significance Index: -77.9500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 123.1405
    Cell Significance Index: -82.6300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 62.2893
    Cell Significance Index: -76.8000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 22.4778
    Cell Significance Index: -60.2200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.2643
    Cell Significance Index: -83.9100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.2785
    Cell Significance Index: -53.0700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.5221
    Cell Significance Index: -20.8400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.7313
    Cell Significance Index: 57.1700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.7301
    Cell Significance Index: 29.6800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.5269
    Cell Significance Index: 87.8100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.4600
    Cell Significance Index: 66.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.4423
    Cell Significance Index: 335.3900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.3496
    Cell Significance Index: 18.7600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.3143
    Cell Significance Index: 284.5600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.1541
    Cell Significance Index: 1176.4100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.1054
    Cell Significance Index: 379.5400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.8731
    Cell Significance Index: 88.0300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.8703
    Cell Significance Index: 43.2100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.8157
    Cell Significance Index: 16.7200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.7076
    Cell Significance Index: 44.9000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.5910
    Cell Significance Index: 102.6500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.5497
    Cell Significance Index: 198.6600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4519
    Cell Significance Index: 288.1400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.4111
    Cell Significance Index: 406.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.4091
    Cell Significance Index: 623.0000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.2867
    Cell Significance Index: 91.0000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.1480
    Cell Significance Index: 85.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0480
    Cell Significance Index: 123.5900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.9920
    Cell Significance Index: 128.1700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8178
    Cell Significance Index: 42.4800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.8133
    Cell Significance Index: 9.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7708
    Cell Significance Index: 154.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.7179
    Cell Significance Index: 19.1700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5474
    Cell Significance Index: 7.0100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4887
    Cell Significance Index: 79.4800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4570
    Cell Significance Index: 412.6400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4459
    Cell Significance Index: 23.4100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4292
    Cell Significance Index: 20.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3957
    Cell Significance Index: 141.9500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3806
    Cell Significance Index: 10.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3072
    Cell Significance Index: 8.8500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2807
    Cell Significance Index: 17.6900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2615
    Cell Significance Index: 16.0700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1664
    Cell Significance Index: 16.4600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1633
    Cell Significance Index: 31.0700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.1618
    Cell Significance Index: 2.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1513
    Cell Significance Index: 25.8300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1236
    Cell Significance Index: 3.6300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0729
    Cell Significance Index: 1.5800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0578
    Cell Significance Index: 42.3600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0227
    Cell Significance Index: 0.3800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0206
    Cell Significance Index: 15.5700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0067
    Cell Significance Index: 12.5900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0046
    Cell Significance Index: -3.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0238
    Cell Significance Index: -43.8900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0291
    Cell Significance Index: -21.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0311
    Cell Significance Index: -47.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0385
    Cell Significance Index: -17.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0407
    Cell Significance Index: -25.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0498
    Cell Significance Index: -31.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0549
    Cell Significance Index: -5.6100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0582
    Cell Significance Index: -79.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0703
    Cell Significance Index: -2.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0923
    Cell Significance Index: -52.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1554
    Cell Significance Index: -32.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1923
    Cell Significance Index: -10.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2465
    Cell Significance Index: -6.6000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.2498
    Cell Significance Index: -4.4100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2981
    Cell Significance Index: -34.1500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3441
    Cell Significance Index: -50.0200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3663
    Cell Significance Index: -42.6900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4396
    Cell Significance Index: -11.2300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4399
    Cell Significance Index: -50.2100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4618
    Cell Significance Index: -2.7900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5818
    Cell Significance Index: -16.2600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5949
    Cell Significance Index: -47.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6494
    Cell Significance Index: -20.8000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7148
    Cell Significance Index: -12.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7258
    Cell Significance Index: -48.8000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.7464
    Cell Significance Index: -57.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7723
    Cell Significance Index: -80.4200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.9320
    Cell Significance Index: -18.1900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.9543
    Cell Significance Index: -13.0200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -1.0833
    Cell Significance Index: -8.3500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1214
    Cell Significance Index: -33.0300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -1.1316
    Cell Significance Index: -9.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.1691
    Cell Significance Index: -51.7100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.3222
    Cell Significance Index: -81.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.3308
    Cell Significance Index: -60.3200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.4221
    Cell Significance Index: -53.8500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.4870
    Cell Significance Index: -39.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.5115
    Cell Significance Index: -36.2500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5434
    Cell Significance Index: -38.5800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.5682
    Cell Significance Index: -40.3100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.5961
    Cell Significance Index: -58.5900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.7692
    Cell Significance Index: -21.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **RNA-binding exonuclease**: The SSB protein exhibits exonuclease activity, which allows it to degrade specific RNA sequences, thereby regulating their stability and stability-related processes. 2. **Small RNA-binding protein**: SSB binds to various small RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs), and tRNAs, modulating their activity and localization. 3. **Translation regulation**: SSB influences translation by binding to mRNA and modifying its 5' cap, thereby controlling the initiation of translation. 4. **Nuclear localization**: SSB is primarily localized to the nucleus, where it regulates RNA stability and translation in the nucleoplasm. **Pathways and Functions:** 1. **Gene expression regulation**: SSB modulates gene expression by regulating the stability and translation of mRNAs, thereby influencing the expression of target genes. 2. **RNA metabolism**: SSB is involved in various RNA metabolism processes, including mRNA catabolism, tRNA processing, and miRNA stability. 3. **Stress granule formation**: SSB is recruited to cytoplasmic stress granules, where it regulates the stability and translation of mRNAs in response to stress. 4. **Viral translation regulation**: SSB is involved in regulating the translation of viral mRNAs, particularly those of IRES-dependent viruses. **Clinical Significance:** 1. **Autoimmune disorders**: Alterations in SSB expression and function have been implicated in autoimmune diseases, such as systemic lupus erythematosus (SLE), where SSB is known as the "Lupus La protein". 2. **Cancer**: Dysregulation of SSB has been observed in various types of cancer, including leukemia, lymphoma, and breast cancer, where it may contribute to tumorigenesis and tumor progression. 3. **Neurological disorders**: SSB has been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and Huntington's disease, where it may contribute to neuronal dysfunction and degeneration. 4. **Viral infections**: SSB may play a role in regulating the translation of viral mRNAs, particularly those of IRES-dependent viruses, which can be exploited by the immune system to combat viral infections. In conclusion, the SSB gene is a critical regulator of RNA stability and translation in eukaryotic cells, and its dysregulation has been implicated in various diseases, including autoimmune disorders, cancer, and neurological disorders. Further research is needed to fully elucidate the functional significance of SSB in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 2857528149

Symbol: LA_HUMAN

Name: Lupus La protein

UniProtKB Accession Codes:

P05455 Q15367 Q53XJ4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 10 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2468131

Title: Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding.

PubMed ID: 2468131

DOI: 10.1093/nar/17.6.2233

PubMed ID: 3192525

Title: Genomic structure and amino acid sequence domains of the human La autoantigen.

PubMed ID: 3192525

DOI: 10.1016/s0021-9258(19)81321-2

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2452201

Title: Characteristics and epitope mapping of a cloned human autoantigen La.

PubMed ID: 2452201

PubMed ID: 3856888

Title: Isolation and analysis of cDNA clones expressing human lupus La antigen.

PubMed ID: 3856888

DOI: 10.1073/pnas.82.7.2115

PubMed ID: 2470590

Title: Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III.

PubMed ID: 2470590

DOI: 10.1002/j.1460-2075.1989.tb03446.x

PubMed ID: 9054510

Title: Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes.

PubMed ID: 9054510

DOI: 10.1016/s0092-8674(00)81913-3

PubMed ID: 12458796

Title: The human La (SS-B) autoantigen interacts with DDX15/hPrp43, a putative DEAH-box RNA helicase.

PubMed ID: 12458796

DOI: 10.1017/s1355838202021076

PubMed ID: 12384597

Title: La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA.

PubMed ID: 12384597

DOI: 10.1093/nar/gkf583

PubMed ID: 14617813

Title: Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes.

PubMed ID: 14617813

DOI: 10.1091/mbc.e03-05-0343

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12842046

Title: Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element.

PubMed ID: 12842046

DOI: 10.1016/s0969-2126(03)00121-7

PubMed ID: 15004549

Title: Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.

PubMed ID: 15004549

DOI: 10.1038/nsmb747

PubMed ID: 16387655

Title: Structural basis for recognition and sequestration of UUU(OH) 3' termini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen.

PubMed ID: 16387655

DOI: 10.1016/j.molcel.2005.10.027

PubMed ID: 18547518

Title: Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein.

PubMed ID: 18547518

DOI: 10.1016/j.str.2008.02.021

Sequence Information:

  • Length: 408
  • Mass: 46837
  • Checksum: EC153C15F9187FC4
  • Sequence:
    • MAENGDNEKM AALEAKICHQ IEYYFGDFNL PRDKFLKEQI KLDEGWVPLE IMIKFNRLNR 
LTTDFNVIVE ALSKSKAELM EISEDKTKIR RSPSKPLPEV TDEYKNDVKN RSVYIKGFPT 
DATLDDIKEW LEDKGQVLNI QMRRTLHKAF KGSIFVVFDS IESAKKFVET PGQKYKETDL 
LILFKDDYFA KKNEERKQNK VEAKLRAKQE QEAKQKLEED AEMKSLEEKI GCLLKFSGDL 
DDQTCREDLH ILFSNHGEIK WIDFVRGAKE GIILFKEKAK EALGKAKDAN NGNLQLRNKE 
VTWEVLEGEV EKEALKKIIE DQQESLNKWK SKGRRFKGKG KGNKAAQPGS GKGKVQFQGK 
KTKFASDDEH DEHDENGATG PVKRAREETD KEEPASKQQK TENGAGDQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.