Details for: EOMES
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hepatic pit cell (CL2000054)
Fold Change: 14.9988
Cell Significance Index: 40.1800 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.6368
Cell Significance Index: 28.6200 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 0.8008
Cell Significance Index: 8.5200 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.7590
Cell Significance Index: 7.8700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.4742
Cell Significance Index: 12.6900 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 0.4416
Cell Significance Index: 3.6200 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 0.3302
Cell Significance Index: 3.4400 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.2586
Cell Significance Index: 1.8800 - Cell Name: activated type II NK T cell (CL0000931)
Fold Change: 0.2187
Cell Significance Index: 0.5600 - Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 0.0793
Cell Significance Index: 0.4600 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 0.0431
Cell Significance Index: 0.4200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0233
Cell Significance Index: 0.4000 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.0139
Cell Significance Index: 0.1000 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.0123
Cell Significance Index: 0.1000 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 0.0029
Cell Significance Index: 0.0300 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0013
Cell Significance Index: -0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0029
Cell Significance Index: -5.4200 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: -0.0045
Cell Significance Index: -0.0400 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.0051
Cell Significance Index: -0.0500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0065
Cell Significance Index: -4.9500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0074
Cell Significance Index: -5.4600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0078
Cell Significance Index: -5.7700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0104
Cell Significance Index: -5.6900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0105
Cell Significance Index: -5.9200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0115
Cell Significance Index: -5.2400 - Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: -0.0140
Cell Significance Index: -0.1300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0193
Cell Significance Index: -5.5400 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.0242
Cell Significance Index: -0.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0247
Cell Significance Index: -4.2100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0253
Cell Significance Index: -5.0300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0286
Cell Significance Index: -5.7400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0297
Cell Significance Index: -5.3600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0347
Cell Significance Index: -4.4500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0360
Cell Significance Index: -5.2400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0364
Cell Significance Index: -5.0000 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.0376
Cell Significance Index: -0.4800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0400
Cell Significance Index: -2.5200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0404
Cell Significance Index: -4.9700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0404
Cell Significance Index: -5.2300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0423
Cell Significance Index: -4.9900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0424
Cell Significance Index: -4.3300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0424
Cell Significance Index: -4.9400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0458
Cell Significance Index: -5.2500 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: -0.0501
Cell Significance Index: -0.3900 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: -0.0515
Cell Significance Index: -0.4400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0553
Cell Significance Index: -2.6000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0594
Cell Significance Index: -0.8500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0636
Cell Significance Index: -3.3400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0698
Cell Significance Index: -5.2000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0712
Cell Significance Index: -1.9900 - Cell Name: lymphocyte (CL0000542)
Fold Change: -0.0742
Cell Significance Index: -1.0100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0742
Cell Significance Index: -4.5600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0781
Cell Significance Index: -1.7100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0820
Cell Significance Index: -6.3000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0824
Cell Significance Index: -5.0500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0839
Cell Significance Index: -5.4100 - Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
Fold Change: -0.0854
Cell Significance Index: -0.8100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0889
Cell Significance Index: -4.9900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0908
Cell Significance Index: -6.1100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0991
Cell Significance Index: -4.6200 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.1007
Cell Significance Index: -1.7100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1044
Cell Significance Index: -4.2800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1135
Cell Significance Index: -2.7500 - Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
Fold Change: -0.1260
Cell Significance Index: -1.1500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1341
Cell Significance Index: -5.9300 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.1360
Cell Significance Index: -0.8900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1378
Cell Significance Index: -5.0600 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.1402
Cell Significance Index: -2.0500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1437
Cell Significance Index: -5.0500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1459
Cell Significance Index: -5.1100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1498
Cell Significance Index: -4.9100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1504
Cell Significance Index: -4.7900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1519
Cell Significance Index: -4.4600 - Cell Name: T cell (CL0000084)
Fold Change: -0.1542
Cell Significance Index: -1.8200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1555
Cell Significance Index: -5.8900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1612
Cell Significance Index: -5.6000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1774
Cell Significance Index: -5.1100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1795
Cell Significance Index: -4.8900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1797
Cell Significance Index: -5.1500 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.1827
Cell Significance Index: -3.1500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1841
Cell Significance Index: -9.3000 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1856
Cell Significance Index: -5.8700 - Cell Name: natural killer cell (CL0000623)
Fold Change: -0.1860
Cell Significance Index: -2.0600 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1891
Cell Significance Index: -3.6900 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1902
Cell Significance Index: -4.7500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1911
Cell Significance Index: -5.6300 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1925
Cell Significance Index: -5.1400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1978
Cell Significance Index: -3.0600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1989
Cell Significance Index: -5.2300 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.2002
Cell Significance Index: -5.1000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.2007
Cell Significance Index: -4.2000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2010
Cell Significance Index: -4.8200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2043
Cell Significance Index: -5.2200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2064
Cell Significance Index: -5.5300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2112
Cell Significance Index: -4.8800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2149
Cell Significance Index: -5.3600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2152
Cell Significance Index: -5.2500 - Cell Name: mature NK T cell (CL0000814)
Fold Change: -0.2196
Cell Significance Index: -2.4800 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: -0.2208
Cell Significance Index: -2.2400 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: -0.2248
Cell Significance Index: -2.3300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1672297350
Symbol: EOMES_HUMAN
Name: Eomesodermin homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10407135
Title: A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain.
PubMed ID: 10407135
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 18316326
Title: Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products.
PubMed ID: 18316326
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 9888994
Title: Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.
PubMed ID: 9888994
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17566017
Title: The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer.
PubMed ID: 17566017
PubMed ID: 17353897
Title: Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis.
PubMed ID: 17353897
DOI: 10.1038/ng1993
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 686
- Mass: 72732
- Checksum: 1A6BA0763C5A6681
- Sequence:
MQLGEQLLVS SVNLPGAHFY PLESARGGSG GSAGHLPSAA PSPQKLDLDK ASKKFSGSLS CEAVSGEPAA ASAGAPAAML SDTDAGDAFA SAAAVAKPGP PDGRKGSPCG EEELPSAAAA AAAAAAAAAA TARYSMDSLS SERYYLQSPG PQGSELAAPC SLFPYQAAAG APHGPVYPAP NGARYPYGSM LPPGGFPAAV CPPGRAQFGP GAGAGSGAGG SSGGGGGPGT YQYSQGAPLY GPYPGAAAAG SCGGLGGLGV PGSGFRAHVY LCNRPLWLKF HRHQTEMIIT KQGRRMFPFL SFNINGLNPT AHYNVFVEVV LADPNHWRFQ GGKWVTCGKA DNNMQGNKMY VHPESPNTGS HWMRQEISFG KLKLTNNKGA NNNNTQMIVL QSLHKYQPRL HIVEVTEDGV EDLNEPSKTQ TFTFSETQFI AVTAYQNTDI TQLKIDHNPF AKGFRDNYDS SHQIVPGGRY GVQSFFPEPF VNTLPQARYY NGERTVPQTN GLLSPQQSEE VANPPQRWLV TPVQQPGTNK LDISSYESEY TSSTLLPYGI KSLPLQTSHA LGYYPDPTFP AMAGWGGRGS YQRKMAAGLP WTSRTSPTVF SEDQLSKEKV KEEIGSSWIE TPPSIKSLDS NDSGVYTSAC KRRRLSPSNS SNENSPSIKC EDINAEEYSK DTSKGMGGYY AFYTTP
Genular Protein ID: 3345280733
Symbol: B7Z4K0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 590
- Mass: 61659
- Checksum: ED45B734FD522570
- Sequence:
MQLGEQLLVS SVNLPGAHFY PLESARGGSG GSAGHLPSAA PSPQKLDLDK ASKKFSGSLS CEAVSGEPAA ASAGAPATML SDTDAGDAFA SAAAVAKPGP PDGRKGSPCG EEELPSAAAG AAAAAAAAAA AATARYSMDS LSSERYYLQS PGPQGSELAA PCSLFPYQAA AGAPHGPVYP APNGARYPYG SMLPPGGFPA AVCPPGRAQF GPGAGAGSGA GGSSGGGGGP GTYQYSQGAP LYGPYPGAAA AGSCGGLGGL GVPGSGFRAH VYLCNRPLWL KFHRHQTEMI ITKQGRRMFP FLSFNINGLN PTAHYNVFVE VVLADPNHWR FQGGKWVTCG KADNNMQGNK MYVHPESPNT GSHWMRQEIS FGKLKLTNNK GANNNNTLPQ ARYYNGERTV PQTNGLLSPQ QSEEVANPPQ RWLVTPVQQP GTNKLDISSY ESEYTSSTLL PYGIKSLPLQ TSHALGYYPD PTFPAMAGWG GRGSYQRKMA AGLPWTSRTS PTVFSEDQLS KEKVKEEIGS SWIETPPSIK SLDSNDSGVY TSACKRRRLS PSNSSNENSP SIKCEDINAE EYSKDTSKGM GGYYAFYTTP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.