NOL3 | ENSG00000140939 | NCBI 8996

Details for: NOL3

Gene ID: 8996

Symbol: NOL3

Ensembl ID: ENSG00000140939

Description: nucleolar protein 3

Associated with

Apoptotic process
(GO:0006915)
Calcium ion binding
(GO:0005509)
Caspase binding
(GO:0089720)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Cytosol
(GO:0005829)
Death effector domain binding
(GO:0035877)
Death receptor binding
(GO:0005123)
Identical protein binding
(GO:0042802)
Inhibition of cysteine-type endopeptidase activity involved in apoptotic process
(GO:1990001)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Mrna splice site recognition
(GO:0006376)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of extrinsic apoptotic signaling pathway
(GO:2001237)
Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
(GO:1903298)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
(GO:1902176)
Negative regulation of release of cytochrome c from mitochondria
(GO:0090201)
Nucleolus
(GO:0005730)
Protein binding
(GO:0005515)
Protein complex oligomerization
(GO:0051259)
Release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
(GO:0014808)
Rna binding
(GO:0003723)
Rna splicing
(GO:0008380)
Sarcoplasmic reticulum
(GO:0016529)

Other Information

Proteins

NOL3_HUMAN

Genular Protein ID: 2461567808

Symbol: NOL3_HUMAN

Name: N/A

UniProtKB Accession Codes:

O60936 B4DFL0 O60937

Database IDs:

Citations:

PubMed ID: 9560245

Title: ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases.

PubMed ID: 9560245

DOI: 10.1073/pnas.95.9.5156

PubMed ID: 10196175

Title: Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c.

PubMed ID: 10196175

DOI: 10.1074/jbc.274.16.10951

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15004034

Title: Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation.

PubMed ID: 15004034

DOI: 10.1074/jbc.m400695200

PubMed ID: 15509781

Title: Calcium binding of ARC mediates regulation of caspase 8 and cell death.

PubMed ID: 15509781

DOI: 10.1128/mcb.24.22.9763-9770.2004

PubMed ID: 16505176

Title: Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress.

PubMed ID: 16505176

DOI: 10.1161/circulationaha.105.576785

PubMed ID: 17142452

Title: The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant.

PubMed ID: 17142452

DOI: 10.1074/jbc.m609186200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25255805

Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.

PubMed ID: 25255805

DOI: 10.1038/ncomms5919

PubMed ID: 22926851

Title: Familial cortical myoclonus with a mutation in NOL3.

PubMed ID: 22926851

DOI: 10.1002/ana.23666

PubMed ID: 25138476

Title: Screening of mutations in NOL3 in a myoclonic syndromes series.

PubMed ID: 25138476

DOI: 10.1007/s00415-014-7463-z

Sequence Information:

Length: 208
Mass: 22629
Checksum: 239EF1A143EF6168
Sequence:

MGNAQERPSE TIDRERKRLV ETLQADSGLL LDALLARGVL TGPEYEALDA LPDAERRVRR 
LLLLVQGKGE AACQELLRCA QRTAGAPDPA WDWQHVGPGY RDRSYDPPCP GHWTPEAPGS 
GTTCPGLPRA SDPDEAGGPE GSEAVQSGTP EEPEPELEAE ASKEAEPEPE PEPELEPEAE 
AEPEPELEPE PDPEPEPDFE ERDESEDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NOL3

Associated with

Other Information

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases. PubMed ID: 9560245

Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c. PubMed ID: 10196175

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The sequence and analysis of duplication-rich human chromosome 16. PubMed ID: 15616553

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. PubMed ID: 15004034

Calcium binding of ARC mediates regulation of caspase 8 and cell death. PubMed ID: 15509781

Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. PubMed ID: 16505176

The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant. PubMed ID: 17142452

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells. PubMed ID: 25255805

Familial cortical myoclonus with a mutation in NOL3. PubMed ID: 22926851

Screening of mutations in NOL3 in a myoclonic syndromes series. PubMed ID: 25138476