Details for: IGFBP4

Gene ID: 3487

Symbol: IGFBP4

Ensembl ID: ENSG00000141753

Description: insulin like growth factor binding protein 4

Associated with

  • Metabolism of proteins
    (R-HSA-392499)
  • Post-translational protein modification
    (R-HSA-597592)
  • Post-translational protein phosphorylation
    (R-HSA-8957275)
  • Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
    (R-HSA-381426)
  • Endoplasmic reticulum lumen
    (GO:0005788)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Insulin-like growth factor i binding
    (GO:0031994)
  • Insulin-like growth factor ii binding
    (GO:0031995)
  • Mapk cascade
    (GO:0000165)
  • Negative regulation of canonical wnt signaling pathway
    (GO:0090090)
  • Positive regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043568)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Protein binding
    (GO:0005515)
  • Regulation of cell growth
    (GO:0001558)
  • Regulation of glucose metabolic process
    (GO:0010906)
  • Regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043567)
  • Response to organic cyclic compound
    (GO:0014070)
  • Signaling receptor binding
    (GO:0005102)
  • Signal transduction
    (GO:0007165)
  • Type b pancreatic cell proliferation
    (GO:0044342)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 335.3366
    Cell Significance Index: -52.1600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 205.9190
    Cell Significance Index: -52.2300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 135.0414
    Cell Significance Index: -55.6300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 107.0908
    Cell Significance Index: -50.5600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.3535
    Cell Significance Index: -52.2200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.8405
    Cell Significance Index: -53.1500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 15.9347
    Cell Significance Index: 204.0700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.0814
    Cell Significance Index: -51.6200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.2813
    Cell Significance Index: -34.6500
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 9.0992
    Cell Significance Index: 160.8000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 6.6805
    Cell Significance Index: 191.5000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 6.6652
    Cell Significance Index: 75.7200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 6.4745
    Cell Significance Index: 889.1400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.3919
    Cell Significance Index: 91.9300
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 4.1830
    Cell Significance Index: 15.5900
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 4.1212
    Cell Significance Index: 19.0400
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.6595
    Cell Significance Index: 19.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.9784
    Cell Significance Index: 147.4500
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.9053
    Cell Significance Index: 11.9300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.8030
    Cell Significance Index: 35.1900
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.6556
    Cell Significance Index: 9.7800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.5325
    Cell Significance Index: 25.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2786
    Cell Significance Index: 698.2600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2276
    Cell Significance Index: 121.4400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.1212
    Cell Significance Index: 6.9000
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.1038
    Cell Significance Index: 3.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0415
    Cell Significance Index: 73.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0149
    Cell Significance Index: 165.0700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0137
    Cell Significance Index: 14.5800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8839
    Cell Significance Index: 24.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8443
    Cell Significance Index: 167.5500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.8426
    Cell Significance Index: 29.2800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.8329
    Cell Significance Index: 21.9000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.8079
    Cell Significance Index: 12.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7341
    Cell Significance Index: 90.2600
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.7196
    Cell Significance Index: 3.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.7051
    Cell Significance Index: 37.0200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.6769
    Cell Significance Index: 4.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5750
    Cell Significance Index: 254.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5709
    Cell Significance Index: 102.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5388
    Cell Significance Index: 486.4900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.5366
    Cell Significance Index: 7.9200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4392
    Cell Significance Index: 51.1900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3621
    Cell Significance Index: 25.0400
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.2570
    Cell Significance Index: 1.5100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2385
    Cell Significance Index: 5.5100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1589
    Cell Significance Index: 2.6600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1451
    Cell Significance Index: 100.3600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1404
    Cell Significance Index: 18.0000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1008
    Cell Significance Index: 5.0900
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.0950
    Cell Significance Index: 0.5000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0760
    Cell Significance Index: 14.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0549
    Cell Significance Index: 41.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0479
    Cell Significance Index: 90.1000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0285
    Cell Significance Index: 0.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0011
    Cell Significance Index: -0.0500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0086
    Cell Significance Index: -0.0700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0097
    Cell Significance Index: -0.3400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0110
    Cell Significance Index: -6.8400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0140
    Cell Significance Index: -0.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0167
    Cell Significance Index: -7.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0305
    Cell Significance Index: -22.6000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0323
    Cell Significance Index: -1.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0353
    Cell Significance Index: -65.1800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0356
    Cell Significance Index: -5.1800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0380
    Cell Significance Index: -21.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0413
    Cell Significance Index: -63.5900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0481
    Cell Significance Index: -65.4600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0590
    Cell Significance Index: -37.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0592
    Cell Significance Index: -21.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0603
    Cell Significance Index: -44.1900
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0750
    Cell Significance Index: -0.6300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0785
    Cell Significance Index: -1.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1131
    Cell Significance Index: -22.7000
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1161
    Cell Significance Index: -0.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1342
    Cell Significance Index: -38.6100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1614
    Cell Significance Index: -33.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1719
    Cell Significance Index: -29.3500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2148
    Cell Significance Index: -21.9400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2215
    Cell Significance Index: -28.6200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3076
    Cell Significance Index: -35.1100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3094
    Cell Significance Index: -6.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3121
    Cell Significance Index: -14.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4304
    Cell Significance Index: -50.7600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4494
    Cell Significance Index: -51.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4599
    Cell Significance Index: -35.3000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4652
    Cell Significance Index: -48.4400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4980
    Cell Significance Index: -25.9400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5574
    Cell Significance Index: -44.1500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.6986
    Cell Significance Index: -30.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7022
    Cell Significance Index: -43.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7091
    Cell Significance Index: -45.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7671
    Cell Significance Index: -47.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7868
    Cell Significance Index: -25.2000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.8031
    Cell Significance Index: -54.0000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.8631
    Cell Significance Index: -54.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.8691
    Cell Significance Index: -48.7700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.9009
    Cell Significance Index: -42.0100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.9156
    Cell Significance Index: -37.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.0144
    Cell Significance Index: -15.2000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** IGFBP4 is a small, secreted protein that belongs to the IGFBP family, which consists of six members (IGFBP1-6). IGFBP4 is distinct from other IGFBPs in its ability to bind both IGF-I and IGF-II with high affinity. This unique property allows IGFBP4 to modulate the activity of these IGFs, which are involved in various cellular processes, including cell proliferation, differentiation, and survival. **Pathways and Functions:** IGFBP4 plays a crucial role in regulating IGF signaling, which is involved in various cellular processes, including: 1. **Cell Growth and Proliferation:** IGFBP4 modulates IGF signaling, influencing cell growth and proliferation. In some tissues, IGFBP4 promotes cell proliferation, while in others, it inhibits it. 2. **Metabolism:** IGFBP4 regulates glucose metabolism by modulating IGF signaling, which is involved in glucose uptake and storage. 3. **Regulation of Insulin-Like Growth Factor Receptor Signaling:** IGFBP4 positively regulates IGF receptor signaling, which is involved in cell growth, differentiation, and survival. 4. **Negative Regulation of Canonical Wnt Signaling:** IGFBP4 negatively regulates canonical Wnt signaling, which is involved in cell proliferation and differentiation. **Signaling Pathways:** IGFBP4 interacts with various signaling pathways, including: 1. **Mapk Cascade:** IGFBP4 positively regulates the Mapk cascade, which is involved in cell proliferation and differentiation. 2. **Insulin-Like Growth Factor Receptor Signaling Pathway:** IGFBP4 positively regulates IGF receptor signaling, which is involved in cell growth, differentiation, and survival. 3. **Negative Regulation of Canonical Wnt Signaling Pathway:** IGFBP4 negatively regulates canonical Wnt signaling, which is involved in cell proliferation and differentiation. **Significantly Expressed Cells:** IGFBP4 is expressed in various cell types, including: 1. **Endocardial Cells:** IGFBP4 is expressed in endocardial cells, which are involved in heart development and function. 2. **Alveolar Capillary Type 1 Endothelial Cells:** IGFBP4 is expressed in alveolar capillary type 1 endothelial cells, which are involved in lung development and function. 3. **Tracheal Goblet Cells:** IGFBP4 is expressed in tracheal goblet cells, which are involved in airway development and function. 4. **Interstitial Cells of Ovary:** IGFBP4 is expressed in interstitial cells of the ovary, which are involved in ovarian function and development. 5. **Fibroblasts of Mammary Gland:** IGFBP4 is expressed in fibroblasts of the mammary gland, which are involved in breast development and function. **Clinical Significance:** IGFBP4 has significant clinical implications in various diseases, including: 1. **Cancer:** IGFBP4 is overexpressed in various cancers, including breast, lung, and colon cancer. Its overexpression is associated with poor prognosis and aggressive tumor behavior. 2. **Cardiovascular Disease:** IGFBP4 is involved in cardiovascular development and function. Its dysregulation is associated with cardiovascular disease, including atherosclerosis and heart failure. 3. **Metabolic Disorders:** IGFBP4 regulates glucose metabolism and insulin sensitivity. Its dysregulation is associated with metabolic disorders, including type 2 diabetes and obesity. In conclusion, IGFBP4 is a multifaceted protein that plays a crucial role in regulating IGF signaling and various cellular processes. Its dysregulation is associated with various diseases, including cancer, cardiovascular disease, and metabolic disorders. Further research is needed to fully understand the mechanisms of IGFBP4 and its role in human disease.

Genular Protein ID: 2807296251

Symbol: IBP4_HUMAN

Name: Insulin-like growth factor-binding protein 4

UniProtKB Accession Codes:

P22692 A0N9W2 B4E351 Q5U012 Q9UCL6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 11 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1704481

Title: Molecular cloning of the cDNAs encoding a novel insulin-like growth factor-binding protein from rat and human.

PubMed ID: 1704481

DOI: 10.1210/mend-4-10-1451

PubMed ID: 1707125

Title: Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation.

PubMed ID: 1707125

DOI: 10.1210/mend-4-12-1806

PubMed ID: 1709161

Title: Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum.

PubMed ID: 1709161

DOI: 10.1016/s0021-9258(18)31549-7

PubMed ID: 9048882

Title: Structural and functional analysis of the 5'-flanking region of the human insulin-like growth factor binding protein (IGFBP)-4 gene.

PubMed ID: 9048882

DOI: 10.1016/s0167-4781(96)00220-5

PubMed ID: 9615225

Title: Structure and transcription regulation of the human insulin-like growth factor binding protein 4 gene (IGFBP4).

PubMed ID: 9615225

DOI: 10.1006/geno.1998.5283

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1709585

Title: Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.

PubMed ID: 1709585

PubMed ID: 1726835

Title: Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system.

PubMed ID: 1726835

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 15642270

Title: Structural basis for the regulation of insulin-like growth factors by IGF binding proteins.

PubMed ID: 15642270

DOI: 10.1016/j.str.2004.11.009

PubMed ID: 16924115

Title: Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins.

PubMed ID: 16924115

DOI: 10.1073/pnas.0605652103

Sequence Information:

  • Length: 258
  • Mass: 27934
  • Checksum: 5E8F4638D99F0A94
  • Sequence:
    • MLPLCLVAAL LLAAGPGPSL GDEAIHCPPC SEEKLARCRP PVGCEELVRE PGCGCCATCA 
LGLGMPCGVY TPRCGSGLRC YPPRGVEKPL HTLMHGQGVC MELAEIEAIQ ESLQPSDKDE 
GDHPNNSFSP CSAHDRRCLQ KHFAKIRDRS TSGGKMKVNG APREDARPVP QGSCQSELHR 
ALERLAASQS RTHEDLYIIP IPNCDRNGNF HPKQCHPALD GQRGKCWCVD RKTGVKLPGG 
LEPKGELDCH QLADSFRE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.