Details for: ILF2

Gene ID: 3608

Symbol: ILF2

Ensembl ID: ENSG00000143621

Description: interleukin enhancer binding factor 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 254.9098
    Cell Significance Index: -39.6500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 143.5134
    Cell Significance Index: -59.1200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 128.2509
    Cell Significance Index: -32.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 122.0163
    Cell Significance Index: -49.5700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 121.5998
    Cell Significance Index: -57.4100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 111.2785
    Cell Significance Index: -57.2400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 85.7647
    Cell Significance Index: -57.5500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 52.7996
    Cell Significance Index: -50.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 43.9594
    Cell Significance Index: -54.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.6577
    Cell Significance Index: -57.8400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.5543
    Cell Significance Index: -36.3100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.4897
    Cell Significance Index: -35.2900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 5.4961
    Cell Significance Index: 59.7500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.7196
    Cell Significance Index: 37.6800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.1397
    Cell Significance Index: 86.6500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 4.0038
    Cell Significance Index: 139.1300
  • Cell Name: germ cell (CL0000586)
    Fold Change: 3.7338
    Cell Significance Index: 28.1900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.3916
    Cell Significance Index: 43.4400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 3.1082
    Cell Significance Index: 81.7300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.8480
    Cell Significance Index: 81.6400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.7236
    Cell Significance Index: 351.8700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.7035
    Cell Significance Index: 201.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.4520
    Cell Significance Index: 115.2400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.9124
    Cell Significance Index: 33.8000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.7914
    Cell Significance Index: 115.5800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.7635
    Cell Significance Index: 48.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.6545
    Cell Significance Index: 227.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5891
    Cell Significance Index: 187.4000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.5260
    Cell Significance Index: 833.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.5123
    Cell Significance Index: 185.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4988
    Cell Significance Index: 243.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.4144
    Cell Significance Index: 625.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.3835
    Cell Significance Index: 97.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.3186
    Cell Significance Index: 61.4800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.2086
    Cell Significance Index: 217.8800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.0977
    Cell Significance Index: 12.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9904
    Cell Significance Index: 51.4500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8032
    Cell Significance Index: 102.9700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7732
    Cell Significance Index: 53.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7453
    Cell Significance Index: 147.9100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.6655
    Cell Significance Index: 17.7700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5901
    Cell Significance Index: 17.3300
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.4127
    Cell Significance Index: 2.5400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3882
    Cell Significance Index: 20.2200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3573
    Cell Significance Index: 7.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3267
    Cell Significance Index: 55.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2925
    Cell Significance Index: 28.9300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2899
    Cell Significance Index: 2.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2814
    Cell Significance Index: 53.5600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2484
    Cell Significance Index: 224.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2196
    Cell Significance Index: 44.0500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2172
    Cell Significance Index: 13.0400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1627
    Cell Significance Index: 3.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1470
    Cell Significance Index: 7.7200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0684
    Cell Significance Index: 1.1500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0572
    Cell Significance Index: 20.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0498
    Cell Significance Index: 1.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0496
    Cell Significance Index: 2.2500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0437
    Cell Significance Index: 33.0700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0036
    Cell Significance Index: 2.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0062
    Cell Significance Index: -4.6000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0113
    Cell Significance Index: -21.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0299
    Cell Significance Index: -3.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0318
    Cell Significance Index: -19.8600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0323
    Cell Significance Index: -18.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0342
    Cell Significance Index: -63.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0413
    Cell Significance Index: -63.5100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0528
    Cell Significance Index: -71.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0568
    Cell Significance Index: -36.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0776
    Cell Significance Index: -2.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0957
    Cell Significance Index: -5.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1034
    Cell Significance Index: -6.5200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1104
    Cell Significance Index: -50.1200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1158
    Cell Significance Index: -24.3800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1321
    Cell Significance Index: -1.1100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1394
    Cell Significance Index: -3.5600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1420
    Cell Significance Index: -16.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1648
    Cell Significance Index: -47.4200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1905
    Cell Significance Index: -6.7000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2159
    Cell Significance Index: -24.7300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2671
    Cell Significance Index: -8.5600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2779
    Cell Significance Index: -40.3900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2863
    Cell Significance Index: -32.6800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3095
    Cell Significance Index: -1.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3563
    Cell Significance Index: -21.9000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4478
    Cell Significance Index: -6.1100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4893
    Cell Significance Index: -38.7500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5489
    Cell Significance Index: -57.1500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5979
    Cell Significance Index: -11.0500
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.6102
    Cell Significance Index: -3.9700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6413
    Cell Significance Index: -49.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6667
    Cell Significance Index: -17.8700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6841
    Cell Significance Index: -18.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7069
    Cell Significance Index: -47.5300
  • Cell Name: theca cell (CL0000503)
    Fold Change: -0.7149
    Cell Significance Index: -4.2000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9353
    Cell Significance Index: -57.3400
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: -0.9483
    Cell Significance Index: -5.3900
  • Cell Name: glioblast (CL0000030)
    Fold Change: -1.0033
    Cell Significance Index: -6.3000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.0410
    Cell Significance Index: -17.8400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.0447
    Cell Significance Index: -10.8200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ILF2 is a transcription factor that belongs to the interferon regulatory factor (IRF) family. It is characterized by its ability to bind to specific DNA sequences, known as interferon-stimulated response elements (ISRE), which are present in the promoter regions of ISG genes. ILF2's expression is induced by interferons (IFNs), which are cytokines that play a pivotal role in the innate immune response. ILF2's binding to ISRE elements enables it to activate the transcription of ISG genes, leading to the production of proteins that are crucial for the defense against viral infections. **Pathways and Functions:** ILF2 is involved in several key pathways that regulate immune responses, including: 1. **Antiviral Mechanism by IFN-Stimulated Genes:** ILF2 is a critical component of the ISG network, which is activated in response to viral infections. ILF2 binds to ISRE elements, leading to the transcriptional activation of ISG genes, including those that encode proteins with antiviral properties, such as protein kinase R (PKR) and 2',5'-oligoadenylate synthetase (2',5'-OAS). 2. **Cytokine Signaling in the Immune System:** ILF2 is also involved in the regulation of cytokine signaling pathways, including the JAK-STAT pathway, which is crucial for the transmission of signals from cytokine receptors to the nucleus. 3. **Double-Stranded RNA Binding:** ILF2 has been shown to bind to double-stranded RNA (dsRNA), which is a hallmark of viral infections. This binding enables ILF2 to regulate the expression of ISG genes and to modulate the antiviral response. **Clinical Significance:** ILF2's dysregulation has been implicated in various immune-related disorders, including: 1. **Viral Infections:** ILF2's ability to regulate the expression of ISG genes makes it a critical component of the innate immune response to viral infections. Dysregulation of ILF2 has been linked to the development of viral infections, such as influenza and HIV. 2. **Autoimmune Diseases:** ILF2's role in regulating cytokine signaling pathways has also been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus. 3. **Cancer:** ILF2's expression has been linked to the development and progression of certain cancers, including leukemia and lymphoma. In conclusion, ILF2 is a critical transcription factor that plays a pivotal role in the regulation of immune responses, particularly in the context of antiviral mechanisms and cytokine signaling. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of ILF2 in maintaining immune homeostasis. Further research on ILF2 is necessary to fully understand its role in immune regulation and to develop novel therapeutic strategies for immune-related disorders.

Genular Protein ID: 2716474421

Symbol: ILF2_HUMAN

Name: Interleukin enhancer-binding factor 2

UniProtKB Accession Codes:

Q12905 A6NDB0 B2R8G7 Q5SR10 Q5SR11 Q7L7R3 Q9BWD4 Q9P1N0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 8 Ensembl 1 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7519613

Title: Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.

PubMed ID: 7519613

DOI: 10.1016/s0021-9258(17)32048-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9442054

Title: DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45.

PubMed ID: 9442054

DOI: 10.1074/jbc.273.4.2136

PubMed ID: 10574923

Title: Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity.

PubMed ID: 10574923

DOI: 10.1074/jbc.274.49.34598

PubMed ID: 11790298

Title: Directed proteomic analysis of the human nucleolus.

PubMed ID: 11790298

DOI: 10.1016/s0960-9822(01)00650-9

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 11739746

Title: The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells.

PubMed ID: 11739746

DOI: 10.1128/mcb.22.1.343-356.2002

PubMed ID: 17890166

Title: The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.

PubMed ID: 17890166

DOI: 10.1016/j.bbapap.2007.07.015

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18458058

Title: Nuclear factor 45 (NF45) is a regulatory subunit of complexes with NF90/110 involved in mitotic control.

PubMed ID: 18458058

DOI: 10.1128/mcb.00120-08

PubMed ID: 21123651

Title: Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense.

PubMed ID: 21123651

DOI: 10.1101/gad.1965010

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26891316

Title: NF45 and NF90 Bind HIV-1 RNA and Modulate HIV Gene Expression.

PubMed ID: 26891316

DOI: 10.3390/v8020047

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 31212927

Title: Cellular Interleukin Enhancer-Binding Factor 2, ILF2, Inhibits Japanese Encephalitis Virus Replication In Vitro.

PubMed ID: 31212927

DOI: 10.3390/v11060559

PubMed ID: 31878072

Title: Enterovirus 71 Represses Interleukin Enhancer-Binding Factor 2 Production and Nucleus Translocation to Antagonize ILF2 Antiviral Effects.

PubMed ID: 31878072

DOI: 10.3390/v12010022

PubMed ID: 32433969

Title: NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay.

PubMed ID: 32433969

DOI: 10.1016/j.celrep.2020.107660

PubMed ID: 33009960

Title: Cereblon Promotes the Ubiquitination and Proteasomal Degradation of Interleukin Enhancer-Binding Factor 2.

PubMed ID: 33009960

DOI: 10.1007/s10930-020-09918-9

Sequence Information:

  • Length: 390
  • Mass: 43062
  • Checksum: 75BAD022DCD4EE01
  • Sequence:
    • MRGDRGRGRG GRFGSRGGPG GGFRPFVPHI PFDFYLCEMA FPRVKPAPDE TSFSEALLKR 
NQDLAPNSAE QASILSLVTK INNVIDNLIV APGTFEVQIE EVRQVGSYKK GTMTTGHNVA 
DLVVILKILP TLEAVAALGN KVVESLRAQD PSEVLTMLTN ETGFEISSSD ATVKILITTV 
PPNLRKLDPE LHLDIKVLQS ALAAIRHARW FEENASQSTV KVLIRLLKDL RIRFPGFEPL 
TPWILDLLGH YAVMNNPTRQ PLALNVAYRR CLQILAAGLF LPGSVGITDP CESGNFRVHT 
VMTLEQQDMV CYTAQTLVRI LSHGGFRKIL GQEGDASYLA SEISTWDGVI VTPSEKAYEK 
PPEKKEGEEE EENTEEPPQG EEEESMETQE

Genular Protein ID: 2423481106

Symbol: Q53FG3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53FG3

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 390
  • Mass: 43048
  • Checksum: 8822C9DF6F8E6A6C
  • Sequence:
    • MRGDRGRGRG GRFGSRGGPG GGFRPFVPHI PFDFYLCEMA FPRVKPAPDE TSFSEALLKR 
NQDLAPNSAE QASILSLVTK INNVVDNLIV APGTFEVQIE EVRQVGSYKK GTMTTGHNVA 
DLVVILKILP TLEAVAALGN KVVESLRAQD PSEVLTMLTN ETGFEISSSD ATVKILITTV 
PPNLRKLDPE LHLDIKVLQS ALAAIRHARW FEENASQSTV KVLIRLLKDL RIRFPGFEPL 
TPWILDLLGH YAVMNNPTRQ PLALNVAYRR CLQILAAGLF LPGSVGITDP CESGNFRVHT 
VMTLEQQDMV CYTAQTLVRI LSHGGFRKIL GQEGDASYLA SEISTWDGVI VTPSEKAYEK 
PPEKKEGEEE EENTEEPPQG EEEESMETQE

Genular Protein ID: 761363138

Symbol: B4DY09_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DY09

Database IDs:

ARBA 3 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 2 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 5 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 352
  • Mass: 38910
  • Checksum: FF13423680CA025D
  • Sequence:
    • MAFPRVKPAP DETSFSEALL KRNQDLAPNS AEQASILSLV TKINNVIDNL IVAPGTFEVQ 
IEEVRQVGSY KKGTMTTGHN VADLVVILKI LPTLEAVAAL GNKVVESLRA QDPSEVLTML 
TNETGFEISS SDATVKILIT TVPPNLRKLD PELHLDIKVL QSALAAIRHA RWFEENASQS 
TVKVLIRLLK DLRIRFPGFE PLTPWILDLL GHYAVMNNPT RQPLALNVAY RRCLQILAAG 
LFLPGSVGIT DPCESGNFRV HTVMTLEQQD MVCYTAQTLV RILSHGGFRK ILGQEGDASY 
LASEISTWDG VIVTPSEKAY EKPPEKKEGE EEEENTEEPP QGEEEESMET QE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.