Details for: STMN1

Gene ID: 3925

Symbol: STMN1

Ensembl ID: ENSG00000117632

Description: stathmin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 346.9087
    Cell Significance Index: -53.9600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 188.5434
    Cell Significance Index: -77.6700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 164.0887
    Cell Significance Index: -77.4700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 162.2741
    Cell Significance Index: -65.9300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 136.2740
    Cell Significance Index: -34.5700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 115.8084
    Cell Significance Index: -77.7100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 70.6263
    Cell Significance Index: -67.4300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 56.4173
    Cell Significance Index: -69.5600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 26.3993
    Cell Significance Index: -70.7200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 21.0259
    Cell Significance Index: -64.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 19.8376
    Cell Significance Index: -78.2800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 17.4900
    Cell Significance Index: 139.6500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 15.1753
    Cell Significance Index: 194.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 14.9795
    Cell Significance Index: 520.5300
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: 13.4303
    Cell Significance Index: 76.3400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 13.0862
    Cell Significance Index: 344.1000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 11.5349
    Cell Significance Index: 88.9100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 10.8683
    Cell Significance Index: 570.6300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 10.4149
    Cell Significance Index: 218.0000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 9.9905
    Cell Significance Index: 108.6100
  • Cell Name: germ cell (CL0000586)
    Fold Change: 8.2629
    Cell Significance Index: 62.3900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.8772
    Cell Significance Index: -17.2400
  • Cell Name: theca cell (CL0000503)
    Fold Change: 7.7838
    Cell Significance Index: 45.7300
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 7.7485
    Cell Significance Index: 37.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 5.5183
    Cell Significance Index: 643.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.4828
    Cell Significance Index: 337.0000
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 5.2926
    Cell Significance Index: 27.8500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 4.5140
    Cell Significance Index: 532.3400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 4.0921
    Cell Significance Index: 98.1400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.0609
    Cell Significance Index: 197.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.5649
    Cell Significance Index: 1400.7400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 2.4996
    Cell Significance Index: 2256.9100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.3190
    Cell Significance Index: 318.4700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.1456
    Cell Significance Index: 120.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1397
    Cell Significance Index: 429.2200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.1390
    Cell Significance Index: 111.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.0713
    Cell Significance Index: 336.8800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.3821
    Cell Significance Index: 611.0600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.2618
    Cell Significance Index: 161.7500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.0021
    Cell Significance Index: 63.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9102
    Cell Significance Index: 180.6300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8391
    Cell Significance Index: 300.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8101
    Cell Significance Index: 22.0500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.7986
    Cell Significance Index: 9.9100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7339
    Cell Significance Index: 90.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5927
    Cell Significance Index: 40.9900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.5607
    Cell Significance Index: 6.3700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3925
    Cell Significance Index: 50.7100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3751
    Cell Significance Index: 11.0200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3310
    Cell Significance Index: 59.6600
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.2634
    Cell Significance Index: 2.3200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2257
    Cell Significance Index: 10.6100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1736
    Cell Significance Index: 2.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1712
    Cell Significance Index: 32.5800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1418
    Cell Significance Index: 14.0300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1411
    Cell Significance Index: 4.5200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0687
    Cell Significance Index: 1.9200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0629
    Cell Significance Index: 2.2100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0128
    Cell Significance Index: 9.4200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0088
    Cell Significance Index: 0.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0184
    Cell Significance Index: -34.6900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0229
    Cell Significance Index: -14.2800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0319
    Cell Significance Index: -23.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0479
    Cell Significance Index: -88.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0530
    Cell Significance Index: -40.1500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0541
    Cell Significance Index: -83.3200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0555
    Cell Significance Index: -75.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0919
    Cell Significance Index: -6.8500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1009
    Cell Significance Index: -64.1000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1020
    Cell Significance Index: -57.5400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1039
    Cell Significance Index: -10.6200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.1406
    Cell Significance Index: -0.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1514
    Cell Significance Index: -25.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1622
    Cell Significance Index: -73.6100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1869
    Cell Significance Index: -39.3800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2032
    Cell Significance Index: -5.1900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2084
    Cell Significance Index: -5.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2153
    Cell Significance Index: -61.9500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2372
    Cell Significance Index: -10.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2779
    Cell Significance Index: -6.0200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2831
    Cell Significance Index: -20.0200
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.2994
    Cell Significance Index: -1.8800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3000
    Cell Significance Index: -8.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3146
    Cell Significance Index: -9.0700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4165
    Cell Significance Index: -9.1200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4221
    Cell Significance Index: -28.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4227
    Cell Significance Index: -48.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4549
    Cell Significance Index: -66.1300
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.4664
    Cell Significance Index: -4.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5431
    Cell Significance Index: -28.2100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.6476
    Cell Significance Index: -7.7200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6502
    Cell Significance Index: -74.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6678
    Cell Significance Index: -52.8900
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.7108
    Cell Significance Index: -8.0300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7366
    Cell Significance Index: -76.7000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.8673
    Cell Significance Index: -52.0700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.9753
    Cell Significance Index: -10.1600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.9934
    Cell Significance Index: -29.2600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0333
    Cell Significance Index: -33.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.1056
    Cell Significance Index: -51.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** Stathmin 1 is a member of the stathmin family of proteins, which are known for their ability to regulate microtubule dynamics. The STMN1 protein is a homodimeric protein, composed of two identical subunits, each containing a conserved coiled-coil domain. This domain is responsible for the protein's ability to bind to microtubules and regulate their polymerization and depolymerization. Stathmin 1 is also a potent inhibitor of microtubule polymerization and a regulator of microtubule-associated protein 1B (MAP1B) activity. **Pathways and Functions** Stathmin 1 is involved in various cellular pathways, including: 1. **Axonogenesis**: Stathmin 1 plays a crucial role in the formation of axonal connections by regulating microtubule polymerization and depolymerization. This process is essential for the establishment of neural circuits and the development of the nervous system. 2. **Microtubule dynamics**: Stathmin 1 regulates microtubule polymerization and depolymerization by binding to microtubules and inhibiting their polymerization. This process is essential for maintaining cellular structure and organization. 3. **Signal transduction**: Stathmin 1 is involved in signal transduction pathways, including the regulation of receptor tyrosine kinase activity and the modulation of stress fiber assembly. 4. **Cytoskeleton regulation**: Stathmin 1 regulates the cytoskeleton by controlling microtubule polymerization and depolymerization, which is essential for maintaining cellular structure and organization. **Clinical Significance** Dysregulation of Stathmin 1 has been implicated in various neurological and psychiatric disorders, including: 1. **Neurodegenerative diseases**: Stathmin 1 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, where microtubule dynamics and cytoskeleton regulation are disrupted. 2. **Neurodevelopmental disorders**: Stathmin 1 has been implicated in neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia, where abnormalities in microtubule dynamics and cytoskeleton regulation are thought to contribute to disease pathology. 3. **Cancer**: Stathmin 1 has been implicated in cancer development and progression, where dysregulation of microtubule dynamics and cytoskeleton regulation can contribute to tumor growth and metastasis. In conclusion, Stathmin 1 is a critical regulator of microtubule dynamics and cytoskeleton organization, and its dysregulation has been implicated in various neurological and psychiatric disorders. Further research is needed to fully understand the mechanisms by which Stathmin 1 regulates cellular processes and to explore its potential as a therapeutic target for disease treatment.

Genular Protein ID: 2247108991

Symbol: STMN1_HUMAN

Name: Stathmin

UniProtKB Accession Codes:

P16949 A2A2D1 B2R4E7 B7Z8N4 D3DPJ5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CPTAC 3 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 Ensembl 5 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2760073

Title: Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species.

PubMed ID: 2760073

DOI: 10.1016/s0021-9258(18)71714-6

PubMed ID: 2358074

Title: A single amino acid difference distinguishes the human and the rat sequences of stathmin, a ubiquitous intracellular phosphoprotein associated with cell regulations.

PubMed ID: 2358074

DOI: 10.1016/0014-5793(90)80266-l

PubMed ID: 1917919

Title: Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia.

PubMed ID: 1917919

DOI: 10.1016/s0021-9258(18)55189-9

PubMed ID: 8906359

Title: Transcriptional and post-transcriptional regulation of pr22 (Op18) with proliferation control.

PubMed ID: 8906359

DOI: 10.1247/csf.21.237

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2546936

Title: Ca2+-dependent and cAMP-dependent control of nicotinic acetylcholine receptor phosphorylation in muscle cells.

PubMed ID: 2546936

DOI: 10.1016/s0021-9258(18)51559-3

PubMed ID: 1737801

Title: Analysis of phosphoprotein p19 by liquid chromatography/mass spectrometry. Identification of two proline-directed serine phosphorylation sites and a blocked amino terminus.

PubMed ID: 1737801

DOI: 10.1016/s0021-9258(19)50759-1

PubMed ID: 8325880

Title: Serine 25 of oncoprotein 18 is a major cytosolic target for the mitogen-activated protein kinase.

PubMed ID: 8325880

DOI: 10.1016/s0021-9258(18)82435-8

PubMed ID: 8245003

Title: Multiple signal transduction pathways induce phosphorylation of serines 16, 25, and 38 of oncoprotein 18 in T lymphocytes.

PubMed ID: 8245003

DOI: 10.1016/s0021-9258(19)74442-1

PubMed ID: 8125092

Title: Cell-cycle-regulated phosphorylation of oncoprotein 18 on Ser16, Ser25 and Ser38.

PubMed ID: 8125092

DOI: 10.1111/j.1432-1033.1994.tb18632.x

PubMed ID: 10675326

Title: Op18/stathmin caps a kinked protofilament-like tubulin tetramer.

PubMed ID: 10675326

DOI: 10.1093/emboj/19.4.572

PubMed ID: 10702243

Title: Probing the native structure of stathmin and its interaction domains with tubulin. Combined use of limited proteolysis, size exclusion chromatography, and mass spectrometry.

PubMed ID: 10702243

DOI: 10.1074/jbc.275.10.6841

PubMed ID: 11415983

Title: Phosphorylation disrupts the central helix in Op18/stathmin and suppresses binding to tubulin.

PubMed ID: 11415983

DOI: 10.1093/embo-reports/kve105

PubMed ID: 12676564

Title: Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP.

PubMed ID: 12676564

DOI: 10.1016/s0888-7543(03)00031-4

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16548883

Title: Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.

PubMed ID: 16548883

DOI: 10.1111/j.1462-5822.2005.00644.x

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 17693683

Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.

PubMed ID: 17693683

DOI: 10.1074/mcp.m700120-mcp200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 149
  • Mass: 17303
  • Checksum: 316426F60DABCD01
  • Sequence:
    • MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER 
RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL 
ERLREKDKHI EEVRKNKESK DPADETEAD

Genular Protein ID: 2483096200

Symbol: A0A140VJW2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJW2

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 7 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 1 PhylomeDB 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Sequence Information:

  • Length: 174
  • Mass: 19824
  • Checksum: 7F66FFAB6C32A5AB
  • Sequence:
    • MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER 
RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL 
ERLREKMYFW THGPGAHPAQ ISAEQSCLHS VPALCPALGL QSALITWSDL SHHH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.