Details for: PAM

Gene ID: 5066

Symbol: PAM

Ensembl ID: ENSG00000145730

Description: peptidylglycine alpha-amidating monooxygenase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 557.5870
    Cell Significance Index: -86.7300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 340.2612
    Cell Significance Index: -86.3100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 224.2275
    Cell Significance Index: -92.3700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 176.1619
    Cell Significance Index: -83.1700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 145.4744
    Cell Significance Index: -59.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 70.3756
    Cell Significance Index: -86.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 61.8805
    Cell Significance Index: -59.0800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 28.6148
    Cell Significance Index: -76.6600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 23.7825
    Cell Significance Index: -52.0500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 22.0905
    Cell Significance Index: -87.1700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.5412
    Cell Significance Index: -60.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 6.3251
    Cell Significance Index: 485.3800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 5.4506
    Cell Significance Index: 132.9900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 4.9109
    Cell Significance Index: 217.2200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 4.7683
    Cell Significance Index: 68.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 4.7172
    Cell Significance Index: 178.6300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 4.4843
    Cell Significance Index: 107.5500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 4.4522
    Cell Significance Index: 65.7300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 4.4048
    Cell Significance Index: 85.9700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.7571
    Cell Significance Index: 230.9300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.3041
    Cell Significance Index: 84.9300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 3.1017
    Cell Significance Index: 66.3000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.8288
    Cell Significance Index: 131.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.7489
    Cell Significance Index: 184.8400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.4654
    Cell Significance Index: 1705.1300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.2823
    Cell Significance Index: 457.8200
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.1014
    Cell Significance Index: 21.8900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.7542
    Cell Significance Index: 50.0600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4817
    Cell Significance Index: 77.1800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.3796
    Cell Significance Index: 494.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.3079
    Cell Significance Index: 73.3900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0613
    Cell Significance Index: 104.9900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0525
    Cell Significance Index: 171.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9356
    Cell Significance Index: 844.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.7398
    Cell Significance Index: 335.7800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6496
    Cell Significance Index: 17.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5929
    Cell Significance Index: 81.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5635
    Cell Significance Index: 307.7400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.4923
    Cell Significance Index: 63.1100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3921
    Cell Significance Index: 6.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3753
    Cell Significance Index: 40.8300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3742
    Cell Significance Index: 576.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.3732
    Cell Significance Index: 688.2500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.2667
    Cell Significance Index: 3.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2139
    Cell Significance Index: 36.5200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1741
    Cell Significance Index: 110.5600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1260
    Cell Significance Index: 171.3500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1071
    Cell Significance Index: 201.7300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0894
    Cell Significance Index: 0.5400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0688
    Cell Significance Index: 13.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0531
    Cell Significance Index: 10.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0481
    Cell Significance Index: 5.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0407
    Cell Significance Index: 1.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0191
    Cell Significance Index: 3.4500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0114
    Cell Significance Index: -0.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0161
    Cell Significance Index: -11.9000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0203
    Cell Significance Index: -0.4400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0311
    Cell Significance Index: -19.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0553
    Cell Significance Index: -40.5100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0627
    Cell Significance Index: -27.7200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0706
    Cell Significance Index: -53.4300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0723
    Cell Significance Index: -40.7900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0841
    Cell Significance Index: -5.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1118
    Cell Significance Index: -23.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1542
    Cell Significance Index: -6.9900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1579
    Cell Significance Index: -20.4100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1936
    Cell Significance Index: -5.4100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2228
    Cell Significance Index: -32.3800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2263
    Cell Significance Index: -26.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2436
    Cell Significance Index: -70.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3452
    Cell Significance Index: -9.9500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3533
    Cell Significance Index: -4.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3788
    Cell Significance Index: -38.6900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5034
    Cell Significance Index: -57.4700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5426
    Cell Significance Index: -56.5000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5635
    Cell Significance Index: -9.4300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.5927
    Cell Significance Index: -40.9900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5945
    Cell Significance Index: -70.1100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.6194
    Cell Significance Index: -7.8000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6195
    Cell Significance Index: -12.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6750
    Cell Significance Index: -35.4400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.6764
    Cell Significance Index: -18.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6787
    Cell Significance Index: -50.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6846
    Cell Significance Index: -41.9700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6923
    Cell Significance Index: -79.3100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.7876
    Cell Significance Index: -9.9400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.7947
    Cell Significance Index: -11.3800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8072
    Cell Significance Index: -57.0900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8378
    Cell Significance Index: -66.3500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.8874
    Cell Significance Index: -57.2500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.9932
    Cell Significance Index: -12.8800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9942
    Cell Significance Index: -21.1000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.0285
    Cell Significance Index: -32.9400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.0671
    Cell Significance Index: -30.5900
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -1.0684
    Cell Significance Index: -13.7000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.2271
    Cell Significance Index: -15.2200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.2391
    Cell Significance Index: -64.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.5030
    Cell Significance Index: -94.7300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.6671
    Cell Significance Index: -57.9300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.7023
    Cell Significance Index: -50.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The PAM gene is characterized by its high expression levels in neuron-associated cells, granule cells, and stellate neurons, highlighting its importance in the nervous system. The enzyme's ability to catalyze the alpha-amidation of peptidylglycine residues is crucial for the production of biologically active peptides, such as neuropeptides and hormones. This post-translational modification is essential for regulating various physiological processes, including neurotransmission, hormone secretion, and immune responses. **Pathways and Functions:** The PAM gene is intricately linked to several signaling pathways that govern various physiological processes. The enzyme's activity is required for the proper functioning of peptide amidation, a process that is essential for: 1. **Neurotransmission:** PAM plays a critical role in regulating the activity of neuropeptides, such as somatostatin and vasoactive intestinal peptide (VIP), which are involved in modulating neurotransmission and hormone secretion. 2. **Hormone Secretion:** The enzyme's activity is necessary for the proper functioning of peptide hormones, such as adrenocorticotropic hormone (ACTH) and thyrotropin-releasing hormone (TRH). 3. **Immune Response:** PAM has been implicated in the regulation of immune responses, particularly in the context of inflammation and immune cell activation. 4. **Cardiac Function:** The enzyme's activity is also required for maintaining cardiac function, as it is involved in regulating the activity of peptide hormones that modulate cardiac contractility and relaxation. **Clinical Significance:** The PAM gene's dysregulation has been implicated in various diseases and disorders, including: 1. **Neurological Disorders:** Alterations in PAM expression have been linked to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Hormonal Imbalances:** Dysregulation of PAM has been implicated in hormonal imbalances, including hypothyroidism and hyperthyroidism. 3. **Cardiovascular Disease:** The enzyme's activity is required for maintaining cardiac function, and alterations in PAM expression have been linked to cardiovascular disease. 4. **Cancer:** PAM has been implicated in cancer development and progression, particularly in the context of tumor cell migration and invasion. In conclusion, the PAM gene is a critical component of the immune system and nervous system, and its dysregulation has far-reaching implications for various diseases and disorders. Further research is necessary to fully elucidate the mechanisms by which PAM regulates physiological processes and to explore its potential therapeutic applications.

Genular Protein ID: 1786306581

Symbol: AMD_HUMAN

Name: Peptidyl-alpha-hydroxyglycine alpha-amidating lyase

UniProtKB Accession Codes:

P19021 A6NMR0 A8K293 O43211 O95080 Q16252 Q16253 Q54A45 Q86U53 Q8WVC7 Q9UCG0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 1 CORUM 1 CTD 1 ChEBI 83 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 EC 2 EMBL 13 Ensembl 6 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 RefSeq 9 Rhea 18 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2357221

Title: Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning and functional expression of a truncated form in COS cells.

PubMed ID: 2357221

DOI: 10.1016/0006-291x(90)90366-u

PubMed ID: 7999037

Title: Isolation and functional expression of human pancreatic peptidylglycine alpha-amidating monooxygenase.

PubMed ID: 7999037

DOI: 10.1006/bbrc.1994.2662

PubMed ID: 12699694

Title: Expression and characterization of human bifunctional peptidylglycine alpha-amidating monooxygenase.

PubMed ID: 12699694

DOI: 10.1016/s1046-5928(02)00684-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

DOI: 10.1101/gr.7.4.353

PubMed ID: 8144680

Title: Alternative splicing governs sulfation of tyrosine or oligosaccharide on peptidylglycine alpha-amidating monooxygenase.

PubMed ID: 8144680

DOI: 10.1016/s0021-9258(17)34149-2

PubMed ID: 10574929

Title: The novel kinase peptidylglycine alpha-amidating monooxygenase cytosolic interactor protein 2 interacts with the cytosolic routing determinants of the peptide processing enzyme peptidylglycine alpha-amidating monooxygenase.

PubMed ID: 10574929

DOI: 10.1074/jbc.274.49.34646

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

  • Length: 973
  • Mass: 108332
  • Checksum: 8A089B657F56EE39
  • Sequence:
    • MAGRVPSLLV LLVFPSSCLA FRSPLSVFKR FKETTRPFSN ECLGTTRPVV PIDSSDFALD 
IRMPGVTPKQ SDTYFCMSMR IPVDEEAFVI DFKPRASMDT VHHMLLFGCN MPSSTGSYWF 
CDEGTCTDKA NILYAWARNA PPTRLPKGVG FRVGGETGSK YFVLQVHYGD ISAFRDNNKD 
CSGVSLHLTR LPQPLIAGMY LMMSVDTVIP AGEKVVNSDI SCHYKNYPMH VFAYRVHTHH 
LGKVVSGYRV RNGQWTLIGR QSPQLPQAFY PVGHPVDVSF GDLLAARCVF TGEGRTEATH 
IGGTSSDEMC NLYIMYYMEA KHAVSFMTCT QNVAPDMFRT IPPEANIPIP VKSDMVMMHE 
HHKETEYKDK IPLLQQPKRE EEEVLDQGDF YSLLSKLLGE REDVVHVHKY NPTEKAESES 
DLVAEIANVV QKKDLGRSDA REGAEHERGN AILVRDRIHK FHRLVSTLRP PESRVFSLQQ 
PPPGEGTWEP EHTGDFHMEE ALDWPGVYLL PGQVSGVALD PKNNLVIFHR GDHVWDGNSF 
DSKFVYQQIG LGPIEEDTIL VIDPNNAAVL QSSGKNLFYL PHGLSIDKDG NYWVTDVALH 
QVFKLDPNNK EGPVLILGRS MQPGSDQNHF CQPTDVAVDP GTGAIYVSDG YCNSRIVQFS 
PSGKFITQWG EESSGSSPLP GQFTVPHSLA LVPLLGQLCV ADRENGRIQC FKTDTKEFVR 
EIKHSSFGRN VFAISYIPGL LFAVNGKPHF GDQEPVQGFV MNFSNGEIID IFKPVRKHFD 
MPHDIVASED GTVYIGDAHT NTVWKFTLTE KLEHRSVKKA GIEVQEIKEA EAVVETKMEN 
KPTSSELQKM QEKQKLIKEP GSGVPVVLIT TLLVIPVVVL LAIAIFIRWK KSRAFGDSEH 
KLETSSGRVL GRFRGKGSGG LNLGNFFASR KGYSRKGFDR LSTEGSDQEK EDDGSESEEE 
YSAPLPALAP SSS

Genular Protein ID: 3701901209

Symbol: A0A804HIQ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HIQ0

Database IDs:

ARBA 20 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 ChEBI 29 DisGeNET 1 EC 2 EMBL 4 Ensembl 2 GO 6 Gene3D 3 GeneTree 1 HGNC 1 InterPro 10 NCBI Taxonomy 1 PANTHER 2 PIRSR 4 PRINTS 1 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 SAM 3 SMR 1 SUPFAM 2

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 867
  • Mass: 96329
  • Checksum: DF0EE46ABC089E76
  • Sequence:
    • MAGRVPSLLV LLVFPSSCLA FRSPLSVFKR FKETTRPFSN ECLGTTRPVV PIDSSDFALD 
IRMPGVTPKQ SDTYFCMSMR IPVDEEAFVI DFKPRASMDT VHHMLLFGCN MPSSTGSYWF 
CDEGTCTDKA NILYAWARNA PPTRLPKGVG FRVGGETGSK YFVLQVHYGD ISAFRDNNKD 
CSGVSLHLTR LPQPLIAGMY LMMSVDTVIP AGEKVVNSDI SCHYKNYPMH VFAYRVHTHH 
LGKVVSGYRV RNGQWTLIGR QSPQLPQAFY PVGHPVDVSF GDLLAARCVF TGEGRTEATH 
IGGTSSDEMC NLYIMYYMEA KHAVSFMTCT QNVAPDMFRT IPPEANIPIP VKSDMVMMHE 
HHKETEYKDK IPLLQQPKRE EEEVLDQDFH MEEALDWPGV YLLPGQVSGV ALDPKNNLVI 
FHRGDHVWDG NSFDSKFVYQ QIGLGPIEED TILVIDPNNA AVLQSSGKNL FYLPHGLSID 
KDGNYWVTDV ALHQVFKLDP NNKEGPVLIL GRSMQPGSDQ NHFCQPTDVA VDPGTGAIYV 
SDGYCNSRIV QFSPSGKFIT QWGEESSGSS PLPGQFTVPH SLALVPLLGQ LCVADRENGR 
IQCFKTDTKE FVREIKHSSF GRNVFAISYI PGLLFAVNGK PHFGDQEPVQ GFVMNFSNGE 
IIDIFKPVRK HFDMPHDIVA SEDGTVYIGD AHTNTVWKFT LTEKLEHRSV KKAGIEVQEI 
KEAEAVVETK MENKPTSSEL QKMQEKQKLI KEPGSGVPVV LITTLLVIPV VVLLAIAIFI 
RWKKSRAFGA DSEHKLETSS GRVLGRFRGK GSGGLNLGNF FASRKGYSRK GFDRLSTEGS 
DQEKEDDGSE SEEEYSAPLP ALAPSSS

Genular Protein ID: 3320701115

Symbol: O43832_HUMAN

Name: N/A

UniProtKB Accession Codes:

O43832

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 7590286

Title: Human peptidylglycine alpha-amidating monooxygenase transcripts derived by alternative mRNA splicing of an unreported exon.

PubMed ID: 7590286

DOI: 10.1016/0378-1119(95)00364-C

Sequence Information:

  • Length: 97
  • Mass: 11020
  • Checksum: 3A7402A2126CF9CE
  • Sequence:
    • AESESDLVAE IANVVQKKDL GRSDAREGAE HERGNAILVR DRIHKFHRLV STLRPPESRV 
FSLQQPPPGE GTWEPEHTGA RREDMKCFQC KEMISVQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.