Details for: RORA

Gene ID: 6095

Symbol: RORA

Ensembl ID: ENSG00000069667

Description: RAR related orphan receptor A

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 8.84
    Marker Score: 28958
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 8.18
    Marker Score: 276163
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 8.17
    Marker Score: 144956
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 7.65
    Marker Score: 5035
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 7.58
    Marker Score: 10664
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 7.5
    Marker Score: 4936
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 6.83
    Marker Score: 5138.5
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 6.51
    Marker Score: 21826
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 6.44
    Marker Score: 3582
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 5.1
    Marker Score: 1324
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 5.05
    Marker Score: 12638
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 4.93
    Marker Score: 20543.5
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 4.59
    Marker Score: 19132
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 4.4
    Marker Score: 5917
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 4.36
    Marker Score: 20193
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 4.34
    Marker Score: 8353
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 4.23
    Marker Score: 3656
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 4.2
    Marker Score: 5078
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 4.1
    Marker Score: 1972
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 4.08
    Marker Score: 1349
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 4
    Marker Score: 2169
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.94
    Marker Score: 3497
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 3.89
    Marker Score: 20410
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.75
    Marker Score: 4253
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.75
    Marker Score: 2604
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 3.71
    Marker Score: 2081
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 3.61
    Marker Score: 4502
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 3.6
    Marker Score: 4142
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.59
    Marker Score: 7871
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 3.51
    Marker Score: 2707
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.4
    Marker Score: 14219
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.26
    Marker Score: 69670
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 3.2
    Marker Score: 1867
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 3.19
    Marker Score: 1679
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.19
    Marker Score: 931
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 3.17
    Marker Score: 1006
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 3.05
    Marker Score: 2904
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.03
    Marker Score: 3777
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.89
    Marker Score: 57466
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.87
    Marker Score: 6603
  • Cell Name: granule cell (CL0000120)
    Fold Change: 2.87
    Marker Score: 21635
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.85
    Marker Score: 899
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.84
    Marker Score: 42445
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.82
    Marker Score: 2448
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.82
    Marker Score: 15163
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 2.8
    Marker Score: 849
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.76
    Marker Score: 21154
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.73
    Marker Score: 103752
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 2.72
    Marker Score: 994
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.69
    Marker Score: 1575
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.68
    Marker Score: 1495
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.63
    Marker Score: 2833
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.62
    Marker Score: 9299
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.62
    Marker Score: 949.5
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 2.61
    Marker Score: 1137
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.6
    Marker Score: 1284
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.58
    Marker Score: 10709
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.58
    Marker Score: 7352.5
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.53
    Marker Score: 4249
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.51
    Marker Score: 1051
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.5
    Marker Score: 1900
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.47
    Marker Score: 2314
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.46
    Marker Score: 8749
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.45
    Marker Score: 1280
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.44
    Marker Score: 90003
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.44
    Marker Score: 1455
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.42
    Marker Score: 2995
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.37
    Marker Score: 7488
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 2.36
    Marker Score: 1667.5
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.33
    Marker Score: 594
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.33
    Marker Score: 2571
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 2.31
    Marker Score: 1189
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.29
    Marker Score: 8850
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.27
    Marker Score: 873
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 2.24
    Marker Score: 2403.5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.21
    Marker Score: 2324
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.18
    Marker Score: 20490
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.17
    Marker Score: 1125
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.17
    Marker Score: 1261
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 2.15
    Marker Score: 2323
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.15
    Marker Score: 794
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.11
    Marker Score: 33837
  • Cell Name: bipolar neuron (CL0000103)
    Fold Change: 2.08
    Marker Score: 700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.07
    Marker Score: 127485
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 2.06
    Marker Score: 769
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.04
    Marker Score: 21113
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 2.02
    Marker Score: 10874
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.01
    Marker Score: 4809
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.01
    Marker Score: 1764
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2
    Marker Score: 621
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 1.99
    Marker Score: 1976
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.99
    Marker Score: 8105
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.96
    Marker Score: 2773
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 1.95
    Marker Score: 1417
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.91
    Marker Score: 2641
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.9
    Marker Score: 18036
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.89
    Marker Score: 599
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.89
    Marker Score: 516
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.89
    Marker Score: 64238
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.88
    Marker Score: 2275

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Other Information

**Key Characteristics:** RORA is a transcription factor that belongs to the nuclear receptor superfamily, which includes other receptors such as PPARα, PPARγ, and RXR. RORA is characterized by its ability to bind to specific DNA sequences, known as response elements, and regulate gene expression by recruiting other transcription factors and coactivators. RORA is also known for its ability to interact with other transcription factors, such as PPARα and PPARγ, to modulate their activity. **Pathways and Functions:** RORA is involved in various biological pathways, including: 1. **Circadian Clock Regulation:** RORA plays a crucial role in regulating the circadian clock by controlling the expression of genes involved in the clock mechanism, such as PER2 and BMAL1. 2. **Immune Regulation:** RORA modulates the activity of immune cells, such as T cells and macrophages, by regulating the expression of genes involved in immune responses, such as cytokines and chemokines. 3. **Metabolic Homeostasis:** RORA regulates lipid metabolism by controlling the expression of genes involved in fatty acid synthesis and degradation, such as PPARα and PPARγ. 4. **Cholesterol Homeostasis:** RORA modulates cholesterol homeostasis by regulating the expression of genes involved in cholesterol synthesis and uptake, such as HMG-CoA reductase and LDLR. 5. **Stress Response:** RORA regulates the expression of genes involved in stress responses, such as heat shock proteins and chaperones. **Clinical Significance:** RORA has been implicated in various diseases, including: 1. **Metabolic Disorders:** RORA has been linked to metabolic disorders, such as obesity and type 2 diabetes, due to its role in regulating lipid metabolism and glucose homeostasis. 2. **Immune-Mediated Diseases:** RORA has been implicated in immune-mediated diseases, such as rheumatoid arthritis and multiple sclerosis, due to its role in regulating immune responses. 3. **Circadian Disorders:** RORA has been linked to circadian disorders, such as delayed sleep phase syndrome and jet lag, due to its role in regulating the circadian clock. 4. **Neurological Disorders:** RORA has been implicated in neurological disorders, such as Parkinson's disease and Alzheimer's disease, due to its role in regulating neuronal function and survival. In conclusion, RORA is a transcription factor that plays a crucial role in various biological processes, including immune regulation, circadian clock, and metabolic homeostasis. Its dysregulation has been implicated in various diseases, highlighting the importance of RORA in maintaining overall health and well-being. **References:** * [Insert references to recent studies on RORA and its role in different diseases] Note: This is a general summary of the gene RORA, and it is not intended to be a comprehensive review of the literature.

Genular Protein ID: 2344009623

Symbol: RORA_HUMAN

Name: Nuclear receptor ROR-alpha

UniProtKB Accession Codes:

P35398 P35397 P35399 P45445 Q495X4 Q96H83

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EMBL 18 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 47 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PIR 4 PRINTS 3 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 7 RefSeq 4 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7926749

Title: Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

PubMed ID: 7926749

DOI: 10.1101/gad.8.5.538

PubMed ID: 7916608

Title: Identification of nuclear receptor mRNAs by RT-PCR amplification of conserved zinc-finger motif sequences.

PubMed ID: 7916608

DOI: 10.1006/bbrc.1993.1976

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9328355

Title: Transcriptional activation and repression by RORalpha, an orphan nuclear receptor required for cerebellar development.

PubMed ID: 9328355

DOI: 10.1210/mend.11.11.0002

PubMed ID: 10478845

Title: Coactivators for the orphan nuclear receptor RORalpha.

PubMed ID: 10478845

DOI: 10.1210/mend.13.9.0343

PubMed ID: 9862959

Title: Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD.

PubMed ID: 9862959

DOI: 10.1093/nar/27.2.411

PubMed ID: 11554739

Title: Identification of a novel peroxisome proliferator-activated receptor (PPAR) gamma promoter in man and transactivation by the nuclear receptor RORalpha1.

PubMed ID: 11554739

DOI: 10.1006/bbrc.2001.5602

PubMed ID: 11252722

Title: The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response.

PubMed ID: 11252722

DOI: 10.1093/embo-reports/kve007

PubMed ID: 11053433

Title: Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha.

PubMed ID: 11053433

DOI: 10.1074/jbc.m004982200

PubMed ID: 14570920

Title: The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation.

PubMed ID: 14570920

DOI: 10.1074/jbc.m308152200

PubMed ID: 14742449

Title: Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1.

PubMed ID: 14742449

DOI: 10.1074/jbc.m313186200

PubMed ID: 15790933

Title: Transcriptional regulation of apolipoprotein A5 gene expression by the nuclear receptor RORalpha.

PubMed ID: 15790933

DOI: 10.1161/01.atv.0000163841.85333.83

PubMed ID: 15781255

Title: Identification of the human ApoAV gene as a novel RORalpha target gene.

PubMed ID: 15781255

DOI: 10.1016/j.bbrc.2005.02.151

PubMed ID: 16462772

Title: RORA, a large common fragile site gene, is involved in cellular stress response.

PubMed ID: 16462772

DOI: 10.1038/sj.onc.1209314

PubMed ID: 17512500

Title: Extracellular signal-regulated kinase-2 phosphorylates RORalpha4 in vitro.

PubMed ID: 17512500

DOI: 10.1016/j.bbrc.2007.05.016

PubMed ID: 18658046

Title: Transcriptional activation of HIF-1 by RORalpha and its role in hypoxia signaling.

PubMed ID: 18658046

DOI: 10.1161/atvbaha.108.171546

PubMed ID: 18354202

Title: Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3.

PubMed ID: 18354202

DOI: 10.4049/jimmunol.180.7.4785

PubMed ID: 18005000

Title: Phosphorylation and transcriptional activity regulation of retinoid-related orphan receptor alpha 1 by protein kinases C.

PubMed ID: 18005000

DOI: 10.1111/j.1471-4159.2007.05074.x

PubMed ID: 19041634

Title: SUMOylation of RORalpha potentiates transcriptional activation function.

PubMed ID: 19041634

DOI: 10.1016/j.bbrc.2008.11.072

PubMed ID: 19381306

Title: Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.

PubMed ID: 19381306

DOI: 10.1621/nrs.07003

PubMed ID: 19965867

Title: Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.

PubMed ID: 19965867

DOI: 10.1074/jbc.m109.080614

PubMed ID: 21628546

Title: Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).

PubMed ID: 21628546

DOI: 10.1177/0748730411401579

PubMed ID: 21499262

Title: Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.

PubMed ID: 21499262

DOI: 10.1038/nature10075

PubMed ID: 22170608

Title: Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.

PubMed ID: 22170608

DOI: 10.1038/nature10700

PubMed ID: 23063525

Title: EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex.

PubMed ID: 23063525

DOI: 10.1016/j.molcel.2012.09.004

PubMed ID: 22789990

Title: Action of RORs and their ligands in (patho)physiology.

PubMed ID: 22789990

DOI: 10.1016/j.tem.2012.05.012

PubMed ID: 29656859

Title: Dual molecular effects of dominant RORA mutations cause two variants of syndromic intellectual disability with either autism or cerebellar ataxia.

PubMed ID: 29656859

DOI: 10.1016/j.ajhg.2018.02.021

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 12467577

Title: X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha.

PubMed ID: 12467577

DOI: 10.1016/s0969-2126(02)00912-7

PubMed ID: 14722075

Title: Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A.

PubMed ID: 14722075

DOI: 10.1074/jbc.m400302200

Sequence Information:

  • Length: 523
  • Mass: 58975
  • Checksum: 0FA43BBCE6E28DC7
  • Sequence:
    • MESAPAAPDP AASEPGSSGA DAAAGSRETP LNQESARKSE PPAPVRRQSY SSTSRGISVT 
KKTHTSQIEI IPCKICGDKS SGIHYGVITC EGCKGFFRRS QQSNATYSCP RQKNCLIDRT 
SRNRCQHCRL QKCLAVGMSR DAVKFGRMSK KQRDSLYAEV QKHRMQQQQR DHQQQPGEAE 
PLTPTYNISA NGLTELHDDL SNYIDGHTPE GSKADSAVSS FYLDIQPSPD QSGLDINGIK 
PEPICDYTPA SGFFPYCSFT NGETSPTVSM AELEHLAQNI SKSHLETCQY LREELQQITW 
QTFLQEEIEN YQNKQREVMW QLCAIKITEA IQYVVEFAKR IDGFMELCQN DQIVLLKAGS 
LEVVFIRMCR AFDSQNNTVY FDGKYASPDV FKSLGCEDFI SFVFEFGKSL CSMHLTEDEI 
ALFSAFVLMS ADRSWLQEKV KIEKLQQKIQ LALQHVLQKN HREDGILTKL ICKVSTLRAL 
CGRHTEKLMA FKAIYPDIVR LHFPPLYKEL FTSEFEPAMQ IDG

Genular Protein ID: 1436332595

Symbol: A0A0C4DFP5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFP5

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 548
  • Mass: 62251
  • Checksum: 505F1369DEFEB3A6
  • Sequence:
    • MNEGAPGDSD LETEARVPWS IMGHCLRTGQ ARMSATPTPA GEGARSSSTC SSLSRLFWSQ 
LEHINWDGAT AKNFINLREF FSFLLPALRK AQIEIIPCKI CGDKSSGIHY GVITCEGCKG 
FFRRSQQSNA TYSCPRQKNC LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF GRMSKKQRDS 
LYAEVQKHRM QQQQRDHQQQ PGEAEPLTPT YNISANGLTE LHDDLSNYID GHTPEGSKAD 
SAVSSFYLDI QPSPDQSGLD INGIKPEPIC DYTPASGFFP YCSFTNGETS PTVSMAELEH 
LAQNISKSHL ETCQYLREEL QQITWQTFLQ EEIENYQNKQ REVMWQLCAI KITEAIQYVV 
EFAKRIDGFM ELCQNDQIVL LKAGSLEVVF IRMCRAFDSQ NNTVYFDGKY ASPDVFKSLG 
CEDFISFVFE FGKSLCSMHL TEDEIALFSA FVLMSADRSW LQEKVKIEKL QQKIQLALQH 
VLQKNHREDG ILTKLICKVS TLRALCGRHT EKLMAFKAIY PDIVRLHFPP LYKELFTSEF 
EPAMQIDG

Genular Protein ID: 1987799638

Symbol: A0A0C4DG53_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DG53

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 468
  • Mass: 53540
  • Checksum: 906C317B11AB3C2D
  • Sequence:
    • MMYFVIAAMK AQIEIIPCKI CGDKSSGIHY GVITCEGCKG FFRRSQQSNA TYSCPRQKNC 
LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF GRMSKKQRDS LYAEVQKHRM QQQQRDHQQQ 
PGEAEPLTPT YNISANGLTE LHDDLSNYID GHTPEGSKAD SAVSSFYLDI QPSPDQSGLD 
INGIKPEPIC DYTPASGFFP YCSFTNGETS PTVSMAELEH LAQNISKSHL ETCQYLREEL 
QQITWQTFLQ EEIENYQNKQ REVMWQLCAI KITEAIQYVV EFAKRIDGFM ELCQNDQIVL 
LKAGSLEVVF IRMCRAFDSQ NNTVYFDGKY ASPDVFKSLG CEDFISFVFE FGKSLCSMHL 
TEDEIALFSA FVLMSADRSW LQEKVKIEKL QQKIQLALQH VLQKNHREDG ILTKLICKVS 
TLRALCGRHT EKLMAFKAIY PDIVRLHFPP LYKELFTSEF EPAMQIDG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.