RPS26 | ENSG00000197728 | NCBI 6231

Details for: RPS26

Gene ID: 6231

Symbol: RPS26

Ensembl ID: ENSG00000197728

Description: ribosomal protein S26

Associated with

Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
(R-HSA-72662)
Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Formation of the ternary complex, and subsequently, the 43s complex
(R-HSA-72695)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Peptide chain elongation
(R-HSA-156902)
Regulation of expression of slits and robos
(R-HSA-9010553)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Ribosomal scanning and start codon recognition
(R-HSA-72702)
Rrna processing
(R-HSA-72312)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1 modulates host translation machinery
(R-HSA-9735869)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov-2 infection
(R-HSA-9694516)
Sars-cov-2 modulates host translation machinery
(R-HSA-9754678)
Sars-cov-2-host interactions
(R-HSA-9705683)
Sars-cov infections
(R-HSA-9679506)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Signaling by robo receptors
(R-HSA-376176)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Translation initiation complex formation
(R-HSA-72649)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Cadherin binding
(GO:0045296)
Cytoplasm
(GO:0005737)
Cytoplasmic side of rough endoplasmic reticulum membrane
(GO:0098556)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic small ribosomal subunit
(GO:0022627)
Extracellular exosome
(GO:0070062)
Membrane
(GO:0016020)
Mrna binding
(GO:0003729)
Negative regulation of rna splicing
(GO:0033119)
Nucleoplasm
(GO:0005654)
Protein binding
(GO:0005515)
Ribosome
(GO:0005840)
Rna binding
(GO:0003723)
Small ribosomal subunit
(GO:0015935)
Structural constituent of ribosome
(GO:0003735)
Synapse
(GO:0045202)
Translation
(GO:0006412)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: embryonic stem cell (CL0002322)
Fold Change: 512.7108
Cell Significance Index: -211.2100
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 417.1585
Cell Significance Index: -196.9500
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 414.2129
Cell Significance Index: -213.0700
Cell Name: ileal goblet cell (CL1000326)
Fold Change: 294.7742
Cell Significance Index: -197.8000
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 28.0306
Cell Significance Index: -75.0900
Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 23.0250
Cell Significance Index: 349.7000
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 16.1929
Cell Significance Index: 433.1500
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 15.0507
Cell Significance Index: 192.7500
Cell Name: abnormal cell (CL0001061)
Fold Change: 12.9060
Cell Significance Index: 1318.3500
Cell Name: pro-T cell (CL0000827)
Fold Change: 11.9968
Cell Significance Index: 306.4800
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 9.2504
Cell Significance Index: 434.7600
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 9.2181
Cell Significance Index: 651.9500
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 8.3148
Cell Significance Index: 153.6800
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 8.1016
Cell Significance Index: 169.5800
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 7.8818
Cell Significance Index: 231.4800
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 7.7633
Cell Significance Index: 88.2000
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.5119
Cell Significance Index: 3321.1900
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 7.1874
Cell Significance Index: 847.6200
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 6.9830
Cell Significance Index: 42.9800
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 6.6110
Cell Significance Index: 812.8800
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 6.5851
Cell Significance Index: 490.7800
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 6.5708
Cell Significance Index: 116.1200
Cell Name: peg cell (CL4033014)
Fold Change: 6.5566
Cell Significance Index: 151.4800
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 6.2918
Cell Significance Index: 68.4000
Cell Name: lactocyte (CL0002325)
Fold Change: 5.9700
Cell Significance Index: 771.2800
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 5.5918
Cell Significance Index: 1008.0200
Cell Name: cell in vitro (CL0001034)
Fold Change: 5.4047
Cell Significance Index: 2951.6200
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 5.3297
Cell Significance Index: 152.7800
Cell Name: kidney cell (CL1000497)
Fold Change: 5.1789
Cell Significance Index: 41.3500
Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 5.0564
Cell Significance Index: 43.4500
Cell Name: early pro-B cell (CL0002046)
Fold Change: 4.7655
Cell Significance Index: 307.4500
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 4.6574
Cell Significance Index: 639.5900
Cell Name: hepatic pit cell (CL2000054)
Fold Change: 4.4011
Cell Significance Index: 11.7900
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 4.3443
Cell Significance Index: 40.0100
Cell Name: granulosa cell (CL0000501)
Fold Change: 3.8642
Cell Significance Index: 101.6100
Cell Name: odontoblast (CL0000060)
Fold Change: 2.9989
Cell Significance Index: 384.4400
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 2.2627
Cell Significance Index: 118.8000
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.2443
Cell Significance Index: 77.9900
Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.9618
Cell Significance Index: 194.0700
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 1.5476
Cell Significance Index: 1171.4300
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9795
Cell Significance Index: 884.4400
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.7836
Cell Significance Index: 149.1200
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.7831
Cell Significance Index: 20.9100
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.3893
Cell Significance Index: 285.4600
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0121
Cell Significance Index: -2.3900
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0479
Cell Significance Index: -90.2000
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1185
Cell Significance Index: -218.5100
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1438
Cell Significance Index: -221.3400
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.1493
Cell Significance Index: -53.5700
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1821
Cell Significance Index: -9.4600
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1821
Cell Significance Index: -247.6700
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.2172
Cell Significance Index: -160.9100
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2373
Cell Significance Index: -11.9900
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2534
Cell Significance Index: -43.2700
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.2782
Cell Significance Index: -45.2400
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2936
Cell Significance Index: -13.6900
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.2998
Cell Significance Index: -190.4200
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.3236
Cell Significance Index: -64.9200
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.3368
Cell Significance Index: -189.9500
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.3606
Cell Significance Index: -225.2100
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.4215
Cell Significance Index: -191.3000
Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.4414
Cell Significance Index: -18.0900
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.5213
Cell Significance Index: -14.1900
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.5612
Cell Significance Index: -161.4800
Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.5952
Cell Significance Index: -8.9700
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.6029
Cell Significance Index: -37.0600
Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7672
Cell Significance Index: -4.6400
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.9064
Cell Significance Index: -103.8400
Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.9248
Cell Significance Index: -55.5200
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -1.0554
Cell Significance Index: -222.2900
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.0566
Cell Significance Index: -83.6800
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.3555
Cell Significance Index: -197.0500
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.4056
Cell Significance Index: -88.5900
Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.4209
Cell Significance Index: -23.7800
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.5618
Cell Significance Index: -33.8400
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.8797
Cell Significance Index: -195.7200
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.9546
Cell Significance Index: -109.6800
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.9554
Cell Significance Index: -62.6300
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -2.0851
Cell Significance Index: -94.5100
Cell Name: paneth cell of colon (CL0009009)
Fold Change: -2.2324
Cell Significance Index: -33.4500
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -2.3677
Cell Significance Index: -181.7000
Cell Name: germ cell (CL0000586)
Fold Change: -2.5256
Cell Significance Index: -19.0700
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -2.8266
Cell Significance Index: -173.3000
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -2.9879
Cell Significance Index: -74.6900
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -2.9973
Cell Significance Index: -201.5400
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -3.2422
Cell Significance Index: -113.9300
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -3.4103
Cell Significance Index: -58.7900
Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -3.4461
Cell Significance Index: -71.8700
Cell Name: perivascular cell (CL4033054)
Fold Change: -3.6017
Cell Significance Index: -16.6300
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -3.8310
Cell Significance Index: -112.8400
Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -3.8656
Cell Significance Index: -32.4700
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -4.0429
Cell Significance Index: -55.1600
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -4.3030
Cell Significance Index: -115.3000
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -4.3758
Cell Significance Index: -193.5500
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -4.5077
Cell Significance Index: -24.5800
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -4.5128
Cell Significance Index: -28.0400
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -4.9176
Cell Significance Index: -180.5200
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -4.9185
Cell Significance Index: -63.3400
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -5.1820
Cell Significance Index: -196.2300
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -5.4515
Cell Significance Index: -140.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** RPS26 is a highly conserved protein, with high sequence similarity across different species. It is a member of the ribosomal protein family, which is essential for the structure and function of the ribosome. RPS26 is a small protein, with a molecular weight of approximately 12 kDa, and is composed of two alpha-helices and a beta-sheet. The protein is highly phosphorylated, which is essential for its proper folding and function. **Pathways and Functions** RPS26 plays a critical role in the following pathways: 1. **Activation of mRNA upon binding of the cap-binding complex and eIFs**: RPS26 binds to the mRNA cap and eIFs, facilitating the recruitment of the 40S subunit to the mRNA. 2. **Translation initiation complex formation**: RPS26 forms a complex with eIF1A and eIF3, which is essential for the recruitment of the 40S subunit to the mRNA. 3. **Translation elongation**: RPS26 plays a role in the elongation phase of translation, where it interacts with the 60S subunit to facilitate the joining of the two subunits. 4. **Eukaryotic translation initiation**: RPS26 is essential for the initiation of translation in eukaryotic cells, where it binds to the mRNA cap and eIFs. **Clinical Significance** Alterations in RPS26 expression have been implicated in various diseases, including: 1. **Cancer**: Overexpression of RPS26 has been observed in several types of cancer, including pancreatic cancer and thyroid cancer. 2. **Infectious diseases**: RPS26 has been shown to be a target of the SARS-CoV-2 virus, which can modulate host translation machinery to facilitate viral replication. 3. **Neurological disorders**: RPS26 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, RPS26 is a critical component of the ribosome, playing a vital role in the initiation of protein synthesis in eukaryotic cells. Alterations in RPS26 expression have been implicated in various diseases, highlighting the importance of this gene in human health and disease. Further research is needed to fully understand the mechanisms by which RPS26 regulates translation and its role in disease.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

40S ribosomal protein S26

Genular Protein ID: 2388612056

Symbol: RS26_HUMAN

Name: 40S ribosomal protein S26

UniProtKB Accession Codes:

P62854 P02383 P70394 Q06722 Q3MHD8 Q6IRY4

Database IDs:

Citations:

PubMed ID: 8464749

Title: S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues.

PubMed ID: 8464749

DOI: 10.1093/nar/21.6.1498

PubMed ID: 7945460

Title: Cloning cDNA of human S26 ribosomal protein and determination of its primary structure.

PubMed ID: 7945460

PubMed ID: 9602156

Title: Isolation, structural analysis and mapping of the functional gene of human ribosomal protein S26.

PubMed ID: 9602156

DOI: 10.1016/s0378-1119(98)00108-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

PubMed ID: 25957688

Title: Structural snapshots of actively translating human ribosomes.

PubMed ID: 25957688

DOI: 10.1016/j.cell.2015.03.052

PubMed ID: 25901680

Title: Structure of the human 80S ribosome.

PubMed ID: 25901680

DOI: 10.1038/nature14427

PubMed ID: 20116044

Title: Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia.

PubMed ID: 20116044

DOI: 10.1016/j.ajhg.2009.12.015

PubMed ID: 24942156

Title: Diamond-Blackfan anemia with mandibulofacial dystostosis is heterogeneous, including the novel DBA genes TSR2 and RPS28.

PubMed ID: 24942156

DOI: 10.1002/ajmg.a.36633

Sequence Information:

Length: 115
Mass: 13015
Checksum: F60DF98F8900D968
Sequence:

MTKKRRNNGR AKKGRGHVQP IRCTNCARCV PKDKAIKKFV IRNIVEAAAV RDISEASVFD 
AYVLPKLYVK LHYCVSCAIH SKVVRNRSRE ARKDRTPPPR FRPAGAAPRP PPKPM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RPS26

Associated with

Cells (max top 100)

Other Information

S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues. PubMed ID: 8464749

Cloning cDNA of human S26 ribosomal protein and determination of its primary structure. PubMed ID: 7945460

Isolation, structural analysis and mapping of the functional gene of human ribosomal protein S26. PubMed ID: 9602156

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. PubMed ID: 8706699

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

A new system for naming ribosomal proteins. PubMed ID: 24524803

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Structures of the human and Drosophila 80S ribosome. PubMed ID: 23636399

Structural snapshots of actively translating human ribosomes. PubMed ID: 25957688

Structure of the human 80S ribosome. PubMed ID: 25901680

Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. PubMed ID: 20116044

Diamond-Blackfan anemia with mandibulofacial dystostosis is heterogeneous, including the novel DBA genes TSR2 and RPS28. PubMed ID: 24942156