Details for: SDCBP

Gene ID: 6386

Symbol: SDCBP

Ensembl ID: ENSG00000137575

Description: syndecan binding protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 626.8916
    Cell Significance Index: -97.5100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 377.8238
    Cell Significance Index: -95.8300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 248.5753
    Cell Significance Index: -102.4000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 229.8132
    Cell Significance Index: -108.5000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 224.9561
    Cell Significance Index: -91.3900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 198.3727
    Cell Significance Index: -102.0400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 161.7830
    Cell Significance Index: -108.5600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 96.4553
    Cell Significance Index: -92.0900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 82.2252
    Cell Significance Index: -101.3800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 33.7382
    Cell Significance Index: -90.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 27.3844
    Cell Significance Index: -108.0600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 24.5942
    Cell Significance Index: -75.5400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.7414
    Cell Significance Index: -36.6400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 6.8150
    Cell Significance Index: 120.4300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 5.5844
    Cell Significance Index: 160.0800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 5.0669
    Cell Significance Index: 36.3900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.4352
    Cell Significance Index: 81.9800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.7809
    Cell Significance Index: 261.4700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.8518
    Cell Significance Index: 134.0300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.2332
    Cell Significance Index: 25.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.0191
    Cell Significance Index: 105.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.8484
    Cell Significance Index: 1009.4600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.5914
    Cell Significance Index: 33.3100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.5391
    Cell Significance Index: 92.4000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4963
    Cell Significance Index: 205.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4680
    Cell Significance Index: 238.7600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3440
    Cell Significance Index: 165.2600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.3187
    Cell Significance Index: 169.0500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.2696
    Cell Significance Index: 33.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1839
    Cell Significance Index: 213.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.0771
    Cell Significance Index: 139.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9701
    Cell Significance Index: 45.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.8061
    Cell Significance Index: 60.0800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6199
    Cell Significance Index: 274.0700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.4837
    Cell Significance Index: 12.7200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4336
    Cell Significance Index: 86.9700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3446
    Cell Significance Index: 9.3800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2700
    Cell Significance Index: 508.3600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2345
    Cell Significance Index: 44.6200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2106
    Cell Significance Index: 75.5600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2046
    Cell Significance Index: 141.5400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1617
    Cell Significance Index: 32.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1151
    Cell Significance Index: 73.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0946
    Cell Significance Index: 16.1500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0910
    Cell Significance Index: 0.5500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0356
    Cell Significance Index: 32.1100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0251
    Cell Significance Index: 1.9200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0176
    Cell Significance Index: 0.3000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0094
    Cell Significance Index: -0.4300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0276
    Cell Significance Index: -2.8200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0287
    Cell Significance Index: -17.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0294
    Cell Significance Index: -22.2400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0328
    Cell Significance Index: -24.3000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0330
    Cell Significance Index: -3.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0484
    Cell Significance Index: -74.5700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0526
    Cell Significance Index: -96.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0576
    Cell Significance Index: -42.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0789
    Cell Significance Index: -107.2300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1364
    Cell Significance Index: -76.9500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1407
    Cell Significance Index: -63.8700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2449
    Cell Significance Index: -4.7800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2630
    Cell Significance Index: -75.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2776
    Cell Significance Index: -58.4800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2834
    Cell Significance Index: -41.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.3879
    Cell Significance Index: -38.3700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3967
    Cell Significance Index: -45.4500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4035
    Cell Significance Index: -46.0600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4313
    Cell Significance Index: -29.0000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5234
    Cell Significance Index: -27.1900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5250
    Cell Significance Index: -15.4200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5271
    Cell Significance Index: -37.2800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.6226
    Cell Significance Index: -38.2700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6464
    Cell Significance Index: -75.3300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6774
    Cell Significance Index: -43.7100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7004
    Cell Significance Index: -24.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.8683
    Cell Significance Index: -23.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.9067
    Cell Significance Index: -31.8600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.9140
    Cell Significance Index: -12.4700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9169
    Cell Significance Index: -95.4700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0217
    Cell Significance Index: -80.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0298
    Cell Significance Index: -54.0700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.2173
    Cell Significance Index: -68.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.2954
    Cell Significance Index: -57.3000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.3019
    Cell Significance Index: -34.8300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.3163
    Cell Significance Index: -42.1600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.3207
    Cell Significance Index: -36.9100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.4602
    Cell Significance Index: -36.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.4966
    Cell Significance Index: -75.6300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.5788
    Cell Significance Index: -9.8100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.7315
    Cell Significance Index: -106.1600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.7354
    Cell Significance Index: -51.1200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.7633
    Cell Significance Index: -66.7700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.8115
    Cell Significance Index: -114.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.9469
    Cell Significance Index: -44.9800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -2.0179
    Cell Significance Index: -16.4600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -2.0707
    Cell Significance Index: -35.4900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -2.0887
    Cell Significance Index: -53.3600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -2.2465
    Cell Significance Index: -32.3100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -2.2490
    Cell Significance Index: -64.1800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -2.2879
    Cell Significance Index: -93.7500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SDCBP is a protein-coding gene that belongs to the syndecan family, which is characterized by its ability to bind to syndecans, a class of transmembrane heparan sulfate proteoglycans. The gene is primarily expressed in cells that require cell-to-cell communication and interaction, such as fibroblasts, myeloid leukocytes, and endothelial cells. SDCBP is also known to interact with various signaling molecules, including receptors, kinases, and transcription factors, which further underscores its role in regulating cellular processes. **Pathways and Functions:** SDCBP is involved in multiple signaling pathways, including: 1. **Actin Cytoskeleton Organization:** SDCBP regulates the organization of the actin cytoskeleton, which is essential for cell migration, adhesion, and shape changes. 2. **Adherens Junctions:** SDCBP interacts with adherens junction proteins, such as cadherins, to maintain cell-to-cell adhesion and tissue integrity. 3. **Axon Guidance:** SDCBP plays a role in the regulation of axon growth and guidance during neural development. 4. **Immune System:** SDCBP is expressed in myeloid leukocytes and regulates immune responses, including phagocytosis and cytokine production. 5. **Neurological Development:** SDCBP is involved in the regulation of neuronal development, including axon guidance and synapse formation. SDCBP also regulates various cellular processes, including: 1. **Cell Migration:** SDCBP promotes cell migration by regulating the organization of the actin cytoskeleton and adhesion molecules. 2. **Cell Growth:** SDCBP regulates cell growth and proliferation by modulating signaling pathways, including the PI3K/AKT and MAPK/ERK pathways. 3. **Exosome Secretion:** SDCBP promotes the secretion of exosomes, which are small vesicles that contain proteins, lipids, and RNA molecules. **Clinical Significance:** SDCBP has been implicated in various diseases, including: 1. **Cancer:** SDCBP overexpression has been observed in various types of cancer, including breast, lung, and colon cancer. 2. **Neurological Disorders:** SDCBP has been linked to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Inflammatory Diseases:** SDCBP plays a role in the regulation of immune responses and has been implicated in inflammatory diseases, such as atherosclerosis and rheumatoid arthritis. In conclusion, the syndecan binding protein (SDCBP) is a multifaceted gene that plays a critical role in various cellular processes, including cell adhesion, migration, and signaling. Its significance in human biology is underscored by its broad expression in various cell types and its involvement in multiple signaling pathways. Further research is needed to fully understand the functions of SDCBP and its role in human disease.

Genular Protein ID: 4139229000

Symbol: SDCB1_HUMAN

Name: Syntenin-1

UniProtKB Accession Codes:

O00560 B2R5Q7 B4DUH3 B7ZLN2 O00173 O43391 Q14CP2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 54 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 55 PDBsum 55 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 5 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9391086

Title: Syntenin, a PDZ protein that binds syndecan cytoplasmic domains.

PubMed ID: 9391086

DOI: 10.1073/pnas.94.25.13683

PubMed ID: 9511750

Title: Melanoma differentiation associated gene-9, mda-9, is a human gamma interferon responsive gene.

PubMed ID: 9511750

DOI: 10.1016/s0378-1119(97)00562-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9883737

Title: PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

PubMed ID: 9883737

DOI: 10.1016/s0896-6273(00)80663-7

PubMed ID: 10230395

Title: A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface.

PubMed ID: 10230395

DOI: 10.1016/s1097-2765(00)80470-0

PubMed ID: 10770943

Title: Syntenin-syndecan binding requires syndecan-synteny and the co-operation of both PDZ domains of syntenin.

PubMed ID: 10770943

DOI: 10.1074/jbc.m002459200

PubMed ID: 11152476

Title: The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.

PubMed ID: 11152476

DOI: 10.1074/jbc.m010647200

PubMed ID: 11432873

Title: Schwannomin isoform-1 interacts with syntenin via PDZ domains.

PubMed ID: 11432873

DOI: 10.1074/jbc.m105792200

PubMed ID: 11179419

Title: Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments.

PubMed ID: 11179419

DOI: 10.1091/mbc.12.2.339

PubMed ID: 11498591

Title: Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting protein.

PubMed ID: 11498591

DOI: 10.1126/science.1059157

PubMed ID: 12643545

Title: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

PubMed ID: 12643545

DOI: 10.1021/pr025562r

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22660413

Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.

PubMed ID: 22660413

DOI: 10.1038/ncb2502

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26032692

Title: Syntenin and syndecan in the biogenesis of exosomes.

PubMed ID: 26032692

DOI: 10.1111/boc.201500010

PubMed ID: 25219541

Title: Targeting tumor invasion: the roles of MDA-9/Syntenin.

PubMed ID: 25219541

DOI: 10.1517/14728222.2014.959495

PubMed ID: 26539120

Title: Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells.

PubMed ID: 26539120

DOI: 10.3389/fphar.2015.00241

PubMed ID: 25893292

Title: Syntenin regulates TGF-beta1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-beta type I receptor internalization.

PubMed ID: 25893292

DOI: 10.1038/onc.2015.100

PubMed ID: 26291527

Title: MDA-9/syntenin control.

PubMed ID: 26291527

DOI: 10.1002/jcp.25136

PubMed ID: 12679023

Title: PDZ tandem of human syntenin: crystal structure and functional properties.

PubMed ID: 12679023

DOI: 10.1016/s0969-2126(03)00052-2

PubMed ID: 12842047

Title: Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm.

PubMed ID: 12842047

DOI: 10.1016/s0969-2126(03)00125-4

PubMed ID: 15081807

Title: The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between macromolecular and small molecule crystallography.

PubMed ID: 15081807

DOI: 10.1016/j.jmb.2004.02.057

PubMed ID: 16533050

Title: The binding of the PDZ tandem of syntenin to target proteins.

PubMed ID: 16533050

DOI: 10.1021/bi052225y

PubMed ID: 27386966

Title: Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.

PubMed ID: 27386966

DOI: 10.1038/ncomms12101

Sequence Information:

  • Length: 298
  • Mass: 32444
  • Checksum: 574E1349F86F949F
  • Sequence:
    • MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS 
LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD 
QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ 
AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE 
INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV

Genular Protein ID: 1783094541

Symbol: B4DHN5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DHN5

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 239
  • Mass: 25968
  • Checksum: C8ECBFCEDF02B3A7
  • Sequence:
    • MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS 
LNEEEIRANV AVVSGAPLQG LVQANSPASL VGLRFGDQVL QINGENCAGW SSDKAHKVLK 
QAFGEKITMT IRDRPFERTI TMHKDSTGHV GFIFKNGKIT SIVKDSSAAR NGLLTEHNIC 
EINGQNVIGL KDSQIADILS TSGTVVTITI MPAFIFEHII KRMAPSIMKS LMDHTIPEV

Genular Protein ID: 3473848320

Symbol: G5EA09_HUMAN

Name: N/A

UniProtKB Accession Codes:

G5EA09

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 3 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 318
  • Mass: 34819
  • Checksum: DEA5027C28090AFB
  • Sequence:
    • MIKLWTNRDL HIIVMVKNPA KMSLYPSLED LKVDKVIQAQ TAFSANPANP AILSEASAPI 
PHDGNLYPRL YPELSQYMGL SLNEEEIRAN VAVVSGAPLQ GLVARPSSIN YMVAPVTGND 
VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ 
INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS 
IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK 
RMAPSIMKSL MDHTIPEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.