Details for: SQLE

Gene ID: 6713

Symbol: SQLE

Ensembl ID: ENSG00000104549

Description: squalene epoxidase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 238.2587
    Cell Significance Index: -37.0600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 138.2650
    Cell Significance Index: -35.0700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 100.6924
    Cell Significance Index: -41.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 87.9221
    Cell Significance Index: -41.5100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 82.4355
    Cell Significance Index: -33.4900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 61.8385
    Cell Significance Index: -41.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 35.2451
    Cell Significance Index: -33.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.2663
    Cell Significance Index: -38.5500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.6480
    Cell Significance Index: -39.2400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.8225
    Cell Significance Index: -38.7600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.9527
    Cell Significance Index: -21.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.1069
    Cell Significance Index: 110.0500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.2317
    Cell Significance Index: 29.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.3761
    Cell Significance Index: 107.7000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.2163
    Cell Significance Index: 115.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9623
    Cell Significance Index: 389.4300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.8274
    Cell Significance Index: 38.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.6444
    Cell Significance Index: 898.0500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.6309
    Cell Significance Index: 85.6300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.5588
    Cell Significance Index: 12.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.5584
    Cell Significance Index: 54.1600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.4284
    Cell Significance Index: 37.5600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2915
    Cell Significance Index: 158.8100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.2856
    Cell Significance Index: 15.9500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1300
    Cell Significance Index: 63.4100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0981
    Cell Significance Index: 29.3200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9968
    Cell Significance Index: 108.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9284
    Cell Significance Index: 151.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9182
    Cell Significance Index: 165.5200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8414
    Cell Significance Index: 50.5100
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.6749
    Cell Significance Index: 7.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6667
    Cell Significance Index: 19.2100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.5629
    Cell Significance Index: 6.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5509
    Cell Significance Index: 16.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5216
    Cell Significance Index: 11.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5186
    Cell Significance Index: 104.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4943
    Cell Significance Index: 36.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3910
    Cell Significance Index: 140.2500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3867
    Cell Significance Index: 23.7700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3750
    Cell Significance Index: 338.6100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3632
    Cell Significance Index: 46.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2824
    Cell Significance Index: 7.0600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2628
    Cell Significance Index: 116.1800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2622
    Cell Significance Index: 181.3700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2563
    Cell Significance Index: 12.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2376
    Cell Significance Index: 6.6400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2285
    Cell Significance Index: 5.2800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2261
    Cell Significance Index: 31.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1951
    Cell Significance Index: 2.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1267
    Cell Significance Index: 12.5300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1007
    Cell Significance Index: 19.1600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1004
    Cell Significance Index: 76.0200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0794
    Cell Significance Index: 0.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0615
    Cell Significance Index: 7.2500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0563
    Cell Significance Index: 1.9800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0544
    Cell Significance Index: 1.3900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0445
    Cell Significance Index: 5.7000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0205
    Cell Significance Index: 31.5400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0199
    Cell Significance Index: 27.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0003
    Cell Significance Index: -0.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0020
    Cell Significance Index: -3.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0040
    Cell Significance Index: -0.6900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0047
    Cell Significance Index: -3.4600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0250
    Cell Significance Index: -18.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0275
    Cell Significance Index: -17.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0415
    Cell Significance Index: -25.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0496
    Cell Significance Index: -27.9800
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.0728
    Cell Significance Index: -0.5500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0749
    Cell Significance Index: -3.4900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0750
    Cell Significance Index: -34.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0902
    Cell Significance Index: -5.8200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1010
    Cell Significance Index: -21.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1029
    Cell Significance Index: -29.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1093
    Cell Significance Index: -6.8900
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.1274
    Cell Significance Index: -0.8000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1279
    Cell Significance Index: -2.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1421
    Cell Significance Index: -7.4000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1446
    Cell Significance Index: -3.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1564
    Cell Significance Index: -15.9800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1584
    Cell Significance Index: -23.0300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1838
    Cell Significance Index: -3.1500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1871
    Cell Significance Index: -13.2300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2012
    Cell Significance Index: -23.4500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2088
    Cell Significance Index: -23.9200
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.2095
    Cell Significance Index: -3.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2154
    Cell Significance Index: -6.9000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2415
    Cell Significance Index: -3.4400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2623
    Cell Significance Index: -7.5200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2638
    Cell Significance Index: -17.7400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3010
    Cell Significance Index: -3.4200
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3023
    Cell Significance Index: -4.2400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3413
    Cell Significance Index: -38.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3673
    Cell Significance Index: -38.2400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3761
    Cell Significance Index: -4.6900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3856
    Cell Significance Index: -29.5900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4174
    Cell Significance Index: -10.0100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.4331
    Cell Significance Index: -3.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4435
    Cell Significance Index: -27.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4585
    Cell Significance Index: -12.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4669
    Cell Significance Index: -36.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SQLE is a membrane-bound enzyme that belongs to the cytochrome P450 superfamily. It is specifically involved in the conversion of squalene to 2,3-oxidosqualene, a critical step in the biosynthesis of cholesterol. SQLE has a high degree of specificity, with a strong affinity for squalene and a low affinity for other substrates. The enzyme is also known for its ability to form a complex with the transcription factor SREBP (Sterol Regulatory Element Binding Protein), which plays a key role in regulating cholesterol biosynthesis. **Pathways and Functions:** SQLE is involved in the following pathways: 1. **Cholesterol Biosynthesis:** SQLE is a key enzyme in the biosynthesis of cholesterol, which is an essential lipid for various cellular processes. 2. **Steroid Biosynthesis:** SQLE is involved in the synthesis of other steroids, including steroid hormones and bile acids. 3. **Lipid Metabolism:** SQLE plays a role in the metabolism of lipids, including the breakdown of cholesterol and other lipids. 4. **Endoplasmic Reticulum (ER) Function:** SQLE is localized to the ER, where it is involved in the synthesis of cholesterol and other lipids. SQLE has several functions, including: 1. **Regulation of Cholesterol Biosynthesis:** SQLE regulates the biosynthesis of cholesterol by forming a complex with SREBP, which in turn modulates the expression of genes involved in cholesterol synthesis. 2. **Maintenance of Cellular Homeostasis:** SQLE helps maintain cellular homeostasis by regulating the levels of cholesterol and other lipids within the cell. 3. **Modulation of Cell Proliferation:** SQLE has been shown to regulate cell proliferation by modulating the expression of genes involved in cell growth and differentiation. **Clinical Significance:** SQLE has several clinical implications, including: 1. **Cholesterol Metabolism Disorders:** Mutations in the SQLE gene have been associated with cholesterol metabolism disorders, including familial hypercholesterolemia. 2. **Cancer:** SQLE has been implicated in the development and progression of certain cancers, including breast and prostate cancer. 3. **Neurological Disorders:** SQLE has been shown to play a role in the development of neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Infectious Diseases:** SQLE has been implicated in the pathogenesis of certain infectious diseases, including tuberculosis and malaria. In conclusion, SQLE is a critical enzyme involved in the biosynthesis of cholesterol and other lipids. Its dysregulation has been implicated in various diseases, including cholesterol metabolism disorders, cancer, and neurological disorders. Further research is needed to fully understand the role of SQLE in human health and disease.

Genular Protein ID: 1601676275

Symbol: ERG1_HUMAN

Name: Squalene monooxygenase

UniProtKB Accession Codes:

Q14534 Q9UEK6 Q9UNR6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 16 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EC 1 EMBL 9 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 3 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9286711

Title: Localization of the squalene epoxidase gene (SQLE) to human chromosome region 8q24.1.

PubMed ID: 9286711

DOI: 10.1006/geno.1997.4825

PubMed ID: 10666321

Title: Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase.

PubMed ID: 10666321

DOI: 10.1006/abbi.1999.1629

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8626488

Title: Transcriptional regulation of squalene epoxidase by sterols and inhibitors in HeLa cells.

PubMed ID: 8626488

DOI: 10.1074/jbc.271.14.8053

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24449766

Title: The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway.

PubMed ID: 24449766

DOI: 10.1128/mcb.01140-13

PubMed ID: 26434806

Title: The Regulatory Domain of Squalene Monooxygenase Contains a Re-entrant Loop and Senses Cholesterol via a Conformational Change.

PubMed ID: 26434806

DOI: 10.1074/jbc.m115.675181

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28972164

Title: A conserved degron containing an amphipathic helix regulates the cholesterol-mediated turnover of human squalene monooxygenase, a rate-limiting enzyme in cholesterol synthesis.

PubMed ID: 28972164

DOI: 10.1074/jbc.m117.794230

PubMed ID: 29765154

Title: The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation.

PubMed ID: 29765154

DOI: 10.1038/s41388-018-0281-5

PubMed ID: 30626872

Title: Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase.

PubMed ID: 30626872

DOI: 10.1038/s41467-018-07928-x

Sequence Information:

  • Length: 574
  • Mass: 63923
  • Checksum: 6957F5CF1F1624C8
  • Sequence:
    • MWTFLGIATF TYFYKKFGDF ITLANREVLL CVLVFLSLGL VLSYRCRHRN GGLLGRQQSG 
SQFALFSDIL SGLPFIGFFW AKSPPESENK EQLEARRRRK GTNISETSLI GTAACTSTSS 
QNDPEVIIVG AGVLGSALAA VLSRDGRKVT VIERDLKEPD RIVGEFLQPG GYHVLKDLGL 
GDTVEGLDAQ VVNGYMIHDQ ESKSEVQIPY PLSENNQVQS GRAFHHGRFI MSLRKAAMAE 
PNAKFIEGVV LQLLEEDDVV MGVQYKDKET GDIKELHAPL TVVADGLFSK FRKSLVSNKV 
SVSSHFVGFL MKNAPQFKAN HAELILANPS PVLIYQISSS ETRVLVDIRG EMPRNLREYM 
VEKIYPQIPD HLKEPFLEAT DNSHLRSMPA SFLPPSSVKK RGVLLLGDAY NMRHPLTGGG 
MTVAFKDIKL WRKLLKGIPD LYDDAAIFEA KKSFYWARKT SHSFVVNILA QALYELFSAT 
DDSLHQLRKA CFLYFKLGGE CVAGPVGLLS VLSPNPLVLI GHFFAVAIYA VYFCFKSEPW 
ITKPRALLSS GAVLYKACSV IFPLIYSEMK YMVH

Genular Protein ID: 3551262024

Symbol: Q5HYI4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5HYI4

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 8 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 Rhea 3 RuleBase 1 SAM 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 574
  • Mass: 63794
  • Checksum: C4C6B0DB5CBB8909
  • Sequence:
    • MWTFLGIATF TYFYKKFGDF ITLANREVLL CVLVFLSLGL VLSYRCRHRN GGLLGRQQSG 
SQFALFSDIL SGLPFIGFFW AKSPPESENK EQLEARRRRK GTNISETSLI GTAACTSTSS 
QNDPEVIIVG AGVLGSALAA VLSRDGRKVT VIERDLKEPD RIVGEFLQPG GYHVLKDLGL 
GDTVEGLDAQ VVNGYMIHDQ ESKSEVQIPY PLSENNQVQS GRAFHHGRFI MSLRKAAMAE 
PNAKFIEGVV LQLLEEDDVV MGVQYKDKET GDIKELHAPL TVVADGLFSK FRKSLVSNKV 
SVSSHFVGFL MKNAPQFKAN HAELILANPG PVLIYQISSS ETRVLVDIRG EMPRNLREYM 
VEKIYPQIPD HLKEPFLEAT DNSHLRSMPA SFLPPSSVKK RGVLLLGDAY NMRHPLTGGG 
MTVAFKDIKL WRKLLKGIPD LYDDAAIFEA KKSFYWARKT SHSFVVNILA QALYELFSAT 
DDSLHQLGKA CFLYFKLGGE CVAGPVGLLS VLSPNPLVLI GHFFAVAIYA VYFCFKSEPW 
ITKPRALLSS GAVLYKACSV IFPLIYSEMK YMVH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.