Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 287.6977
Cell Significance Index: -44.7500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 175.8374
Cell Significance Index: -44.6000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 106.9796
Cell Significance Index: -44.0700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 83.6859
Cell Significance Index: -39.5100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 36.3030
Cell Significance Index: -44.7600 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 23.5859
Cell Significance Index: 124.1100 - Cell Name: theca cell (CL0000503)
Fold Change: 12.7353
Cell Significance Index: 74.8200 - Cell Name: perivascular cell (CL4033054)
Fold Change: 11.9574
Cell Significance Index: 55.2100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.2847
Cell Significance Index: -44.5300 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 9.9565
Cell Significance Index: 108.2400 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 9.8400
Cell Significance Index: 158.7700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.3570
Cell Significance Index: -18.2900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 7.6072
Cell Significance Index: 185.6100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 5.3066
Cell Significance Index: 728.7500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 5.2992
Cell Significance Index: 67.8700 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 5.0333
Cell Significance Index: 31.1400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 5.0261
Cell Significance Index: 105.2100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.8185
Cell Significance Index: 109.4600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.9909
Cell Significance Index: 52.8500 - Cell Name: odontoblast (CL0000060)
Fold Change: 2.9630
Cell Significance Index: 379.8400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.7313
Cell Significance Index: 73.1900 - Cell Name: germ cell (CL0000586)
Fold Change: 2.4852
Cell Significance Index: 18.7700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.9628
Cell Significance Index: 150.6200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.8241
Cell Significance Index: 26.9300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.6567
Cell Significance Index: 315.2900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.2002
Cell Significance Index: 544.7500 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.0060
Cell Significance Index: 8.4500 - Cell Name: supporting cell (CL0000630)
Fold Change: 0.9050
Cell Significance Index: 4.1800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.7859
Cell Significance Index: 429.1800 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.7407
Cell Significance Index: 5.5500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.5943
Cell Significance Index: 61.8800 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.5785
Cell Significance Index: 6.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5155
Cell Significance Index: 83.8400 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.3324
Cell Significance Index: 2.8800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2160
Cell Significance Index: 10.1500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.1855
Cell Significance Index: 3.1100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1817
Cell Significance Index: 17.9700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1288
Cell Significance Index: 242.4900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1221
Cell Significance Index: 3.2100 - Cell Name: chondroblast (CL0000058)
Fold Change: 0.1158
Cell Significance Index: 0.6800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0715
Cell Significance Index: 8.3300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0387
Cell Significance Index: 4.7600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0322
Cell Significance Index: 14.2200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0045
Cell Significance Index: 0.3100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0070
Cell Significance Index: -4.4800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0200
Cell Significance Index: -30.7700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0211
Cell Significance Index: -38.9700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0253
Cell Significance Index: -0.7300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0292
Cell Significance Index: -0.7300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0326
Cell Significance Index: -5.8700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0346
Cell Significance Index: -25.6600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0428
Cell Significance Index: -26.7500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0441
Cell Significance Index: -59.9800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0471
Cell Significance Index: -35.6400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0496
Cell Significance Index: -36.3400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0546
Cell Significance Index: -1.9200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0579
Cell Significance Index: -20.7900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0619
Cell Significance Index: -34.9200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0731
Cell Significance Index: -14.6600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0805
Cell Significance Index: -3.6500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0996
Cell Significance Index: -2.5600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1201
Cell Significance Index: -23.8400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1382
Cell Significance Index: -17.8600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1440
Cell Significance Index: -41.4300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1606
Cell Significance Index: -3.4800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1657
Cell Significance Index: -28.2900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1705
Cell Significance Index: -24.7900 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1713
Cell Significance Index: -2.6500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1817
Cell Significance Index: -18.5600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1942
Cell Significance Index: -40.9100 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: -0.2231
Cell Significance Index: -1.0800 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: -0.2617
Cell Significance Index: -0.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2677
Cell Significance Index: -19.9600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2680
Cell Significance Index: -16.0900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2809
Cell Significance Index: -32.1800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2971
Cell Significance Index: -19.1700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3256
Cell Significance Index: -37.1700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3297
Cell Significance Index: -23.3200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3321
Cell Significance Index: -39.1700 - Cell Name: embryonic fibroblast (CL2000042)
Fold Change: -0.3449
Cell Significance Index: -1.6500 - Cell Name: basal-myoepithelial cell of mammary gland (CL0002324)
Fold Change: -0.3600
Cell Significance Index: -2.6700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3600
Cell Significance Index: -11.5300 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: -0.3880
Cell Significance Index: -2.4400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4442
Cell Significance Index: -27.3000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4584
Cell Significance Index: -15.9300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4836
Cell Significance Index: -38.3000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.5187
Cell Significance Index: -14.8000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5501
Cell Significance Index: -25.6500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5880
Cell Significance Index: -36.0500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5936
Cell Significance Index: -16.5900 - Cell Name: muscle cell (CL0000187)
Fold Change: -0.6319
Cell Significance Index: -6.0500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.6483
Cell Significance Index: -43.5900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6851
Cell Significance Index: -34.6300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7194
Cell Significance Index: -45.3400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.7444
Cell Significance Index: -38.6700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7472
Cell Significance Index: -39.2300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7527
Cell Significance Index: -42.2400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.7916
Cell Significance Index: -15.4500 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.7970
Cell Significance Index: -32.6600 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.8220
Cell Significance Index: -10.5400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3449325580
Symbol: TPM2_HUMAN
Name: Tropomyosin beta chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3865200
Title: A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism.
PubMed ID: 3865200
PubMed ID: 3368322
Title: Complete nucleotide sequence of the adult skeletal isoform of human skeletal muscle beta-tropomyosin.
PubMed ID: 3368322
PubMed ID: 2059197
Title: A cDNA encoding a muscle-type tropomyosin cloned from a human epithelial cell line: identity with human fibroblast tropomyosin TM1.
PubMed ID: 2059197
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2303454
Title: A nonmuscle tropomyosin is encoded by the smooth/skeletal beta-tropomyosin gene and its RNA is transcribed from an internal promoter.
PubMed ID: 2303454
PubMed ID: 11840567
Title: Cluster analysis of an extensive human breast cancer cell line protein expression map database.
PubMed ID: 11840567
DOI: 10.1002/1615-9861(200202)2:2<212::aid-prot212>3.0.co;2-h
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 11738357
Title: Mutations in the beta-tropomyosin (TPM2) gene -- a rare cause of nemaline myopathy.
PubMed ID: 11738357
PubMed ID: 12592607
Title: Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes.
PubMed ID: 12592607
DOI: 10.1086/368294
PubMed ID: 17846275
Title: Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2).
PubMed ID: 17846275
PubMed ID: 17339586
Title: Distal arthrogryposis and muscle weakness associated with a beta-tropomyosin mutation.
PubMed ID: 17339586
PubMed ID: 17434307
Title: Cap disease caused by heterozygous deletion of the beta-tropomyosin gene TPM2.
PubMed ID: 17434307
PubMed ID: 19047562
Title: New morphologic and genetic findings in cap disease associated with beta-tropomyosin (TPM2) mutations.
PubMed ID: 19047562
PubMed ID: 19345583
Title: Cap disease due to mutation of the beta-tropomyosin gene (TPM2).
PubMed ID: 19345583
PubMed ID: 23678273
Title: First Korean family with a mutation in TPM2 associated with Sheldon-Hall syndrome.
PubMed ID: 23678273
PubMed ID: 24692096
Title: Mutation update and genotype-phenotype correlations of novel and previously described mutations in TPM2 and TPM3 causing congenital myopathies.
PubMed ID: 24692096
DOI: 10.1002/humu.22554
PubMed ID: 30285720
Title: Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families.
PubMed ID: 30285720
Sequence Information:
- Length: 284
- Mass: 32851
- Checksum: 18E330568E14E0BE
- Sequence:
MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKEAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAMKDEEK MELQEMQLKE AKHIAEDSDR KYEEVARKLV ILEGELERSE ERAEVAESKC GDLEEELKIV TNNLKSLEAQ ADKYSTKEDK YEEEIKLLEE KLKEAETRAE FAERSVAKLE KTIDDLEDEV YAQKMKYKAI SEELDNALND ITSL
Genular Protein ID: 6141089
Symbol: A7XZE4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 284
- Mass: 33026
- Checksum: C1D4A215BBA197C1
- Sequence:
MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKEAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAMKDEEK MELQEMQLKE AKHIAEDSDR KYEEVARKLV ILEGELERSE ERAEVAESRA RQLEEELRTM DQALKSLMAS EEEYSTKEDK YEEEIKLLEE KLKEAETRAE FAERSVAKLE KTIDDLEDEV YAQKMKYKAI SEELDNALND ITSL
Genular Protein ID: 3517933103
Symbol: Q5TCU3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 284
- Mass: 32815
- Checksum: 817AF2EB91639EB5
- Sequence:
MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKEAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAMKDEEK MELQEMQLKE AKHIAEDSDR KYEEVARKLV ILEGELERSE ERAEVAESKC GDLEEELKIV TNNLKSLEAQ ADKYSTKEDK YEEEIKLLEE KLKEAETRAE FAERSVAKLE KTIDDLEETL ASAKEENVEI HQTLDQTLLE LNNL
Genular Protein ID: 476369656
Symbol: V9HW25_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 284
- Mass: 32990
- Checksum: 584D60A8A4D6E9CA
- Sequence:
MDAIKKKMQM LKLDKENAID RAEQAEADKK QAEDRCKQLE EEQQALQKKL KGTEDEVEKY SESVKEAQEK LEQAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ENRAMKDEEK MELQEMQLKE AKHIAEDSDR KYEEVARKLV ILEGELERSE ERAEVAESRA RQLEEELRTM DQALKSLMAS EEEYSTKEDK YEEEIKLLEE KLKEAETRAE FAERSVAKLE KTIDDLEETL ASAKEENVEI HQTLDQTLLE LNNL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.