Details for: SKAP1

Gene ID: 8631

Symbol: SKAP1

Ensembl ID: ENSG00000141293

Description: src kinase associated phosphoprotein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 79.9124
    Cell Significance Index: -12.4300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 43.3680
    Cell Significance Index: -11.0000
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 13.9386
    Cell Significance Index: 37.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.5438
    Cell Significance Index: -13.0000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.9167
    Cell Significance Index: -12.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.8107
    Cell Significance Index: 102.1100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 3.4523
    Cell Significance Index: 101.3900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.7877
    Cell Significance Index: 60.4000
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.3028
    Cell Significance Index: 23.0900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 2.3027
    Cell Significance Index: 72.8300
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.1245
    Cell Significance Index: 6.4800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3284
    Cell Significance Index: 30.6900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.7679
    Cell Significance Index: 8.1700
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.7195
    Cell Significance Index: 7.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7180
    Cell Significance Index: 71.0300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4893
    Cell Significance Index: 10.4200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4648
    Cell Significance Index: 4.2800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4618
    Cell Significance Index: 75.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4027
    Cell Significance Index: 20.9200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3948
    Cell Significance Index: 42.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3810
    Cell Significance Index: 6.5300
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: 0.3601
    Cell Significance Index: 4.6100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2960
    Cell Significance Index: 161.6600
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.2739
    Cell Significance Index: 2.6700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2541
    Cell Significance Index: 29.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2477
    Cell Significance Index: 44.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2220
    Cell Significance Index: 44.0500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1856
    Cell Significance Index: 11.1400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1711
    Cell Significance Index: 11.8300
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.1487
    Cell Significance Index: 1.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1309
    Cell Significance Index: 6.1500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1255
    Cell Significance Index: 25.1800
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.1178
    Cell Significance Index: 1.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1055
    Cell Significance Index: 20.0700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0853
    Cell Significance Index: 1.7700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0839
    Cell Significance Index: 10.3200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0677
    Cell Significance Index: 1.9500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0439
    Cell Significance Index: 2.9500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0371
    Cell Significance Index: 25.6300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0283
    Cell Significance Index: 20.7600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0219
    Cell Significance Index: 0.7700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0131
    Cell Significance Index: 17.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0054
    Cell Significance Index: 8.2600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0049
    Cell Significance Index: 9.1600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0016
    Cell Significance Index: 2.9300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0005
    Cell Significance Index: -0.2000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0067
    Cell Significance Index: -0.1300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0088
    Cell Significance Index: -0.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0094
    Cell Significance Index: -1.2200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0146
    Cell Significance Index: -10.8500
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.0147
    Cell Significance Index: -0.0800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0163
    Cell Significance Index: -12.3600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0174
    Cell Significance Index: -9.8400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0178
    Cell Significance Index: -3.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0184
    Cell Significance Index: -11.7100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0215
    Cell Significance Index: -13.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0225
    Cell Significance Index: -6.4800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0239
    Cell Significance Index: -10.8400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0258
    Cell Significance Index: -1.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0285
    Cell Significance Index: -1.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0368
    Cell Significance Index: -5.3500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0421
    Cell Significance Index: -1.8600
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.0486
    Cell Significance Index: -0.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0594
    Cell Significance Index: -6.0700
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0597
    Cell Significance Index: -1.0300
  • Cell Name: lung resident memory CD8-positive, alpha-beta T cell (CL4033039)
    Fold Change: -0.0599
    Cell Significance Index: -0.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0631
    Cell Significance Index: -13.2900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0737
    Cell Significance Index: -2.3600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0789
    Cell Significance Index: -10.8400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0795
    Cell Significance Index: -3.0100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0881
    Cell Significance Index: -11.3000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1010
    Cell Significance Index: -6.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1017
    Cell Significance Index: -11.6500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1042
    Cell Significance Index: -4.8600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1146
    Cell Significance Index: -13.3600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1181
    Cell Significance Index: -9.0700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1236
    Cell Significance Index: -12.8700
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.1286
    Cell Significance Index: -1.7500
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.1298
    Cell Significance Index: -1.0100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1299
    Cell Significance Index: -1.8600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1432
    Cell Significance Index: -11.3400
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1454
    Cell Significance Index: -1.3600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.1493
    Cell Significance Index: -2.3100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1624
    Cell Significance Index: -2.7400
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.1684
    Cell Significance Index: -1.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1844
    Cell Significance Index: -10.3500
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.1845
    Cell Significance Index: -2.1500
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.1913
    Cell Significance Index: -1.6300
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.2004
    Cell Significance Index: -1.9000
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: -0.2005
    Cell Significance Index: -1.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2120
    Cell Significance Index: -13.0300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2153
    Cell Significance Index: -5.7600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2254
    Cell Significance Index: -3.2300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.2349
    Cell Significance Index: -3.9900
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.2372
    Cell Significance Index: -2.2800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2384
    Cell Significance Index: -6.4900
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.2439
    Cell Significance Index: -3.0900
  • Cell Name: blood cell (CL0000081)
    Fold Change: -0.2464
    Cell Significance Index: -2.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2482
    Cell Significance Index: -16.0100
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.2625
    Cell Significance Index: -3.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SKAP1 is a cytoplasmic protein that localizes to the plasma membrane and is involved in the regulation of integrin activation, cell-cell adhesion, and leukocyte migration. Its unique structure, featuring SH2 and SH3 domains, enables it to interact with various signaling molecules, including src kinases, integrins, and cytoskeletal proteins. SKAP1 is highly expressed in immune cells, including T cells, B cells, and dendritic cells, suggesting its critical role in immune cell function and regulation. **Pathways and Functions:** SKAP1 is involved in multiple signaling pathways that regulate immune cell function, including: 1. **Adaptive immune response:** SKAP1 regulates the activation and proliferation of T cells, ensuring proper immune response to pathogens. 2. **Cell-cell adhesion:** SKAP1 interacts with integrins and other adhesion molecules to regulate cell-cell adhesion, facilitating leukocyte migration and tissue homing. 3. **Cytoskeletal organization:** SKAP1 modulates cytoskeletal dynamics, influencing cell shape, motility, and adhesion. 4. **Transcriptional regulation:** SKAP1 regulates the activity of transcription factors, such as NF-κB, to control gene expression in immune cells. **Clinical Significance:** SKAP1's dysregulation has been implicated in various immune-related disorders, including: 1. **Autoimmune diseases:** Altered SKAP1 expression and function have been linked to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 2. **Cancer:** SKAP1's role in regulating cell-cell adhesion and migration has been implicated in cancer progression and metastasis. 3. **Infectious diseases:** SKAP1's involvement in the adaptive immune response has been linked to susceptibility to certain infectious diseases, such as HIV-1 and tuberculosis. In conclusion, SKAP1 is a complex protein that plays a crucial role in regulating immune cell function, cell-cell adhesion, and signaling pathways. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of understanding SKAP1's mechanisms of action in the context of human disease. **Future Directions:** Further research is needed to fully elucidate SKAP1's role in immune cell function and regulation. Potential areas of investigation include: 1. **SKAP1's role in cancer:** Investigating SKAP1's involvement in cancer progression and metastasis. 2. **SKAP1's interaction with other signaling molecules:** Elucidating the specific interactions between SKAP1 and other signaling molecules to understand its regulatory mechanisms. 3. **SKAP1's therapeutic potential:** Exploring the therapeutic potential of targeting SKAP1 in immune-related disorders. By continuing to unravel the mysteries of SKAP1, we may uncover new therapeutic strategies for treating immune-related diseases and improve our understanding of the complex interactions between immune cells and their microenvironment.

Genular Protein ID: 4009097982

Symbol: SKAP1_HUMAN

Name: Src kinase-associated phosphoprotein 1

UniProtKB Accession Codes:

Q86WV1 D3DTV1 O15268

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 23 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9195899

Title: Molecular cloning of SKAP55, a novel protein that associates with p59fyn in human T-lymphocytes.

PubMed ID: 9195899

DOI: 10.1074/jbc.272.26.16077

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9748251

Title: Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130.

PubMed ID: 9748251

DOI: 10.1074/jbc.273.40.25789

PubMed ID: 9671755

Title: FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells.

PubMed ID: 9671755

DOI: 10.1073/pnas.95.15.8779

PubMed ID: 10856234

Title: SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55.

PubMed ID: 10856234

DOI: 10.1093/emboj/19.12.2889

PubMed ID: 12171928

Title: SKAP55 recruits to lipid rafts and positively mediates the MAPK pathway upon T cell receptor activation.

PubMed ID: 12171928

DOI: 10.1074/jbc.m206023200

PubMed ID: 11909961

Title: SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription.

PubMed ID: 11909961

DOI: 10.1128/mcb.22.8.2673-2686.2002

PubMed ID: 12652296

Title: SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates.

PubMed ID: 12652296

DOI: 10.1038/ni913

PubMed ID: 15849195

Title: Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells.

PubMed ID: 15849195

DOI: 10.1074/jbc.m413201200

PubMed ID: 15939789

Title: An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R.

PubMed ID: 15939789

DOI: 10.1084/jem.20042577

PubMed ID: 16461356

Title: Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein.

PubMed ID: 16461356

DOI: 10.1074/jbc.m508774200

PubMed ID: 16980616

Title: The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1.

PubMed ID: 16980616

DOI: 10.1128/mcb.00331-06

PubMed ID: 17658605

Title: SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1.

PubMed ID: 17658605

DOI: 10.1016/j.molimm.2007.05.024

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 27335501

Title: ARAP, a novel adaptor protein, is required for TCR signaling and integrin-mediated adhesion.

PubMed ID: 27335501

DOI: 10.4049/jimmunol.1501913

Sequence Information:

  • Length: 359
  • Mass: 41432
  • Checksum: 630FE4C17295BD6D
  • Sequence:
    • MQAAALPEEI RWLLEDAEEF LAEGLRNENL SAVARDHRDH ILRGFQQIKA RYYWDFQPQG 
GDIGQDSSDD NHSGTLGLSL TSDAPFLSDY QDEGMEDIVK GAQELDNVIK QGYLEKKSKD 
HSFFGSEWQK RWCVVSRGLF YYYANEKSKQ PKGTFLIKGY GVRMAPHLRR DSKKESCFEL 
TSQDRRSYEF TATSPAEARD WVDQISFLLK DLSSLTIPYE EDEEEEEKEE TYDDIDGFDS 
PSCGSQCRPT ILPGSVGIKE PTEEKEEEDI YEVLPDEEHD LEEDESGTRR KGVDYASYYQ 
GLWDCHGDQP DELSFQRGDL IRILSKEYNM YGWWVGELNS LVGIVPKEYL TTAFEVEER

Genular Protein ID: 2741902162

Symbol: V9HW03_HUMAN

Name: N/A

UniProtKB Accession Codes:

V9HW03

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 2 Gene3D 3 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 Pfam 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 358
  • Mass: 41333
  • Checksum: 158BBE1D48539DAC
  • Sequence:
    • MQAAALPEEI RWLLEDAEEF LAEGLRNENL SAVARDHRDH ILRGFQQIKA RYYWDFQPQG 
GDIGQDSSDD NHSGTLGLSL TSDAPFLSDY QDEGMEDIVK GAQELDNVIK QGYLEKKSKD 
HSFFGSEWQK RWCVVSRGLF YYYANEKSKQ PKGTFLIKGY GVRMAPHLRR DSKKESCFEL 
TSQDRRSYEF TATSPAEARD WVDQISFLLK DLSSLTIPYE EDEEEEEKEE TYDDIDGFDS 
PSCGSQCRPT ILPGSVGIKE PTEEKEEEDI YEVLPDEEHD LEEDESGTRR KGDYASYYQG 
LWDCHGDQPD ELSFQRGDLI RILSKEYNMY GWWVGELNSL VGIVPKEYLT TAFEVEER

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.