Details for: SYT7

Gene ID: 9066

Symbol: SYT7

Ensembl ID: ENSG00000011347

Description: synaptotagmin 7

Associated with

Other Information

Genular Protein ID: 1043847668

Symbol: SYT7_HUMAN

Name: IPCA-7

UniProtKB Accession Codes:

O43581 F5GZC2 F5GZU9 F5H126 F5H1N2 F5H6C1 Q08AH6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CORUM 1 CTD 1 ChEBI 23 ChiTaRS 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 7 EPD 1 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 42 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 5 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9615227

Title: Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes.

PubMed ID: 9615227

DOI: 10.1006/geno.1998.5291

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11342594

Title: The Exocytosis-regulatory protein synaptotagmin VII mediates cell invasion by Trypanosoma cruzi.

PubMed ID: 11342594

DOI: 10.1084/jem.193.9.1097

PubMed ID: 12071850

Title: Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human.

PubMed ID: 12071850

DOI: 10.1042/bj20011877

PubMed ID: 15811535

Title: Trypanosoma cruzi invades synaptotagmin VII-deficient cells by a PI-3 kinase independent pathway.

PubMed ID: 15811535

DOI: 10.1016/j.molbiopara.2005.01.016

PubMed ID: 22966849

Title: Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7.

PubMed ID: 22966849

DOI: 10.1021/bi3007115

PubMed ID: 25437758

Title: Lateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.

PubMed ID: 25437758

DOI: 10.1021/bi5012223

PubMed ID: 26322740

Title: Membrane docking of the synaptotagmin 7 C2A domain: electron paramagnetic resonance measurements show contributions from two membrane binding loops.

PubMed ID: 26322740

DOI: 10.1021/acs.biochem.5b00421

PubMed ID: 26333120

Title: Membrane docking of the synaptotagmin 7 C2A Domain: computation reveals interplay between electrostatic and hydrophobic contributions.

PubMed ID: 26333120

DOI: 10.1021/acs.biochem.5b00422

Sequence Information:

  • Length: 403
  • Mass: 45501
  • Checksum: C9BFB26D298EDBE4
  • Sequence:
    • MYRDPEAASP GAPSRDVLLV SAIITVSLSV TVVLCGLCHW CQRKLGKRYK NSLETVGTPD 
SGRGRSEKKA IKLPAGGKAV NTAPVPGQTP HDESDRRTEP RSSVSDLVNS LTSEMLMLSP 
GSEEDEAHEG CSRENLGRIQ FSVGYNFQES TLTVKIMKAQ ELPAKDFSGT SDPFVKIYLL 
PDKKHKLETK VKRKNLNPHW NETFLFEGFP YEKVVQRILY LQVLDYDRFS RNDPIGEVSI 
PLNKVDLTQM QTFWKDLKPC SDGSGSRGEL LLSLCYNPSA NSIIVNIIKA RNLKAMDIGG 
TSDPYVKVWL MYKDKRVEKK KTVTMKRNLN PIFNESFAFD IPTEKLRETT IIITVMDKDK 
LSRNDVIGKI YLSWKSGPGE VKHWKDMIAR PRQPVAQWHQ LKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.