Details for: R3HCC1
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 9.03rCSI 29.29%PRS 87.25
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CSI 5.94rCSI 13.16%PRS 89.07
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CSI 5.56rCSI 24.48%PRS 78.46
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CSI 5.07rCSI 7.78%PRS 94.67
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CSI 4.98rCSI 5.76%PRS 83.37
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CSI 4.56rCSI 4.24%PRS 90.34
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CSI 4.42rCSI 7.95%PRS 83.89
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CSI 4.4rCSI 3.35%PRS 97.14
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CSI 4.38rCSI 8.79%PRS 82.56
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CSI 4.25rCSI 2.95%PRS 96.54
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CSI 3.85rCSI 2.69%PRS 92.22
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CSI 3.57rCSI 2.81%PRS 91.7
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CSI 3.49rCSI 3.64%PRS 88.1
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CSI 3.45rCSI 4.72%PRS 92.32
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CSI 3.44rCSI 3.38%PRS 90.89
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CSI 3.28rCSI 3.94%PRS 87.86
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CSI 3.24rCSI 5.21%PRS 81.12
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CSI 2.91rCSI 2.16%PRS 95.43
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CSI 2.9rCSI 2.29%PRS 81.49
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CSI 2.87rCSI 8.07%PRS 85.12
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CSI 2.84rCSI 4.23%PRS 88.13
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CSI 2.76rCSI 8.14%PRS 89.49
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CSI 2.71rCSI 2.38%PRS 92.55
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CSI 2.69rCSI 1.79%PRS 90.84
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CSI 2.68rCSI 2.59%PRS 84.73
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CSI 2.65rCSI 2.19%PRS 89.97
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CSI 2.63rCSI 3.35%PRS 92.93
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CSI 2.53rCSI 2.65%PRS 91.2
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CSI 2.48rCSI 4.37%PRS 74.74
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CSI 2.39rCSI 3.87%PRS 83.56
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CSI 2.25rCSI 2.99%PRS 92.24
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CSI 2.2rCSI 2.83%PRS 85.76
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CSI 2.2rCSI 2.2%PRS 83.51
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CSI 2.16rCSI 1.99%PRS 90.23
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CSI 2.14rCSI 3.26%PRS 86.03
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CSI 2.13rCSI 1.73%PRS 88.46
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CSI 2.09rCSI 3.68%PRS 85
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CSI 2.03rCSI 1.79%PRS 80.31
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CSI 2.01rCSI 2.32%PRS 81.99
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CSI 2.01rCSI 10.09%PRS 96.34
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CSI 1.99rCSI 2.74%PRS 97.4
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CSI 1.97rCSI 1.78%PRS 88.04
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CSI 1.95rCSI 2.95%PRS 93.1
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CSI 1.94rCSI 1.57%PRS 90.65
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CSI 1.93rCSI 2.64%PRS 87.83
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CSI 1.88rCSI 2.69%PRS 89.47
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CSI 1.81rCSI 2.66%PRS 84.41
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CSI 1.8rCSI 2.49%PRS 87.68
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CSI 1.76rCSI 5.51%PRS 76.63
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CSI 1.74rCSI 1.51%PRS 91.4
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CSI 1.71rCSI 2.34%PRS 88.28
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CSI 1.68rCSI 2.25%PRS 86.5
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CSI 1.67rCSI 2.28%PRS 82.52
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CSI 1.65rCSI 2.25%PRS 93.99
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CSI 1.63rCSI 2.6%PRS 81.56
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CSI 1.61rCSI 3.43%PRS 83.26
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CSI 1.61rCSI 2.83%PRS 92.1
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CSI 1.49rCSI 3.32%PRS 93.58
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CSI 1.22rCSI 3.09%PRS 83.94
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CSI 1.16rCSI 3.06%PRS 93.19
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CSI 0.89rCSI 3.96%PRS 89.7
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CSI 0.85rCSI 9.55%PRS 92.2
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CSI 0.82rCSI 2.37%PRS 88.26
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CSI 0.81rCSI 2.61%PRS 89.1
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CSI 0.41rCSI 2.34%PRS 91.56
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CSI 0.41rCSI 3.19%PRS 91.16
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 4197206320
Symbol: R3HC1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 440
- Mass: 49092
- Checksum: C035A7E2E3F957C5
- Sequence:
MALLCLDGVF LSSAENDFVH RIQEELDRFL LQKQLSKVLL FPPLSSRLRY LIHRTAENFD LLSSFSVGEG WKRRTVICHQ DIRVPSSDGL SGPCRAPASC PSRYHGPRPI SNQGAAAVPR GARAGRWYRG RKPDQPLYVP RVLRRQEEWG LTSTSVLKRE APAGRDPEEP GDVGAGDPNS DQGLPVLMTQ GTEDLKGPGQ RCENEPLLDP VGPEPLGPES QSGKGDMVEM ATRFGSTLQL DLEKGKESLL EKRLVAEEEE DEEEVEEDGP SSCSEDDYSE LLQEITDNLT KKEIQIEKIH LDTSSFVEEL PGEKDLAHVV EIYDFEPALK TEDLLATFSE FQEKGFRIQW VDDTHALGIF PCLASAAEAL TREFSVLKIR PLTQGTKQSK LKALQRPKLL RLVKERPQTN ATVARRLVAR ALGLQHKKKE RPAVRGPLPP