Details for: FKBP1A

Gene ID: 2280

Symbol: FKBP1A

Ensembl ID: ENSG00000088832

Description: FKBP prolyl isomerase 1A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 416.8563
    Cell Significance Index: -64.8400
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 227.2740
    Cell Significance Index: -93.6300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 204.5786
    Cell Significance Index: -51.8900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 191.3936
    Cell Significance Index: -77.7600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 178.8518
    Cell Significance Index: -84.4400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 164.6043
    Cell Significance Index: -84.6700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 126.1061
    Cell Significance Index: -84.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 62.6705
    Cell Significance Index: -77.2700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 22.3086
    Cell Significance Index: -68.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.5522
    Cell Significance Index: -81.1000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.5935
    Cell Significance Index: -36.4200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 7.9335
    Cell Significance Index: 140.2000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 5.5425
    Cell Significance Index: 62.9700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 5.3461
    Cell Significance Index: 98.8100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 3.9799
    Cell Significance Index: 116.8900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 3.8931
    Cell Significance Index: 27.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.2405
    Cell Significance Index: 152.3000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 3.0118
    Cell Significance Index: 104.6600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.8187
    Cell Significance Index: 332.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.7388
    Cell Significance Index: 376.1200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 2.7036
    Cell Significance Index: 56.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.6355
    Cell Significance Index: 69.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.4297
    Cell Significance Index: 298.7500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.3733
    Cell Significance Index: 21.8600
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.3070
    Cell Significance Index: 18.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.2319
    Cell Significance Index: 288.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.1226
    Cell Significance Index: 1159.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9239
    Cell Significance Index: 346.8200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.7213
    Cell Significance Index: 121.7400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.7039
    Cell Significance Index: 126.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.6826
    Cell Significance Index: 108.5500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6517
    Cell Significance Index: 331.3300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5560
    Cell Significance Index: 687.9600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.5210
    Cell Significance Index: 43.6000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.0597
    Cell Significance Index: 11.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.0278
    Cell Significance Index: 15.4000
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.9802
    Cell Significance Index: 10.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9465
    Cell Significance Index: 121.3400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.8702
    Cell Significance Index: 11.1500
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.6468
    Cell Significance Index: 3.8000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6462
    Cell Significance Index: 63.9200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.6339
    Cell Significance Index: 3.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5919
    Cell Significance Index: 15.8600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5905
    Cell Significance Index: 112.3700
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.5623
    Cell Significance Index: 8.5400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4916
    Cell Significance Index: 22.9200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4755
    Cell Significance Index: 24.7000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3431
    Cell Significance Index: 58.5800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3359
    Cell Significance Index: 7.7600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3141
    Cell Significance Index: 8.5500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.2215
    Cell Significance Index: 167.6600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2099
    Cell Significance Index: 75.2800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1264
    Cell Significance Index: 2.1200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0752
    Cell Significance Index: 3.8000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0378
    Cell Significance Index: 1.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0110
    Cell Significance Index: -8.1300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0149
    Cell Significance Index: -1.5300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0396
    Cell Significance Index: -24.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0418
    Cell Significance Index: -78.7300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0458
    Cell Significance Index: -33.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0582
    Cell Significance Index: -107.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0696
    Cell Significance Index: -107.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0797
    Cell Significance Index: -108.3700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0874
    Cell Significance Index: -3.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1044
    Cell Significance Index: -58.8600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1246
    Cell Significance Index: -3.9900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1259
    Cell Significance Index: -79.9500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1347
    Cell Significance Index: -3.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1674
    Cell Significance Index: -35.2500
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.1903
    Cell Significance Index: -1.6400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1933
    Cell Significance Index: -87.7200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2152
    Cell Significance Index: -25.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2249
    Cell Significance Index: -64.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3454
    Cell Significance Index: -9.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3518
    Cell Significance Index: -40.3100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3601
    Cell Significance Index: -9.2000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3627
    Cell Significance Index: -41.4000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.3748
    Cell Significance Index: -74.3800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5892
    Cell Significance Index: -85.6400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5929
    Cell Significance Index: -36.4500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5936
    Cell Significance Index: -12.8600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.6208
    Cell Significance Index: -25.4400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7112
    Cell Significance Index: -31.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7886
    Cell Significance Index: -82.1100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8167
    Cell Significance Index: -64.6800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.8769
    Cell Significance Index: -39.7500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.8848
    Cell Significance Index: -33.5100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.9005
    Cell Significance Index: -69.1000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.9808
    Cell Significance Index: -28.8900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.0867
    Cell Significance Index: -30.3700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.1005
    Cell Significance Index: -57.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.1133
    Cell Significance Index: -62.4700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.1352
    Cell Significance Index: -59.1300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.1474
    Cell Significance Index: -72.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.2791
    Cell Significance Index: -86.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.3766
    Cell Significance Index: -84.4000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.6000
    Cell Significance Index: -21.8300
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: -1.6849
    Cell Significance Index: -10.5500
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: -1.7333
    Cell Significance Index: -6.0300
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -1.8291
    Cell Significance Index: -14.4400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** FKBP1A exhibits several key characteristics that make it an essential component of the immune system and cellular homeostasis: 1. **Peptidyl-prolyl cis-trans isomerase activity**: FKBP1A possesses a unique peptidyl-prolyl cis-trans isomerase activity, which allows it to catalyze the cis-trans isomerization of proline residues in proteins. This activity is crucial for protein folding and stability. 2. **Calcium signaling**: FKBP1A interacts with calcineurin, a calcium/calmodulin-dependent protein phosphatase, to regulate calcium signaling pathways. This interaction is essential for the proper functioning of the immune system and cellular homeostasis. 3. **Immune response regulation**: FKBP1A plays a crucial role in regulating the immune response by modulating the activity of various signaling pathways, including the NF-κB and TGF-β pathways. 4. **Cellular localization**: FKBP1A is primarily localized to the cytosol and sarcoplasmic reticulum, where it interacts with various proteins and regulates cellular processes. **Pathways and Functions** FKBP1A is involved in various cellular pathways and processes, including: 1. **Protein folding and maturation**: FKBP1A regulates protein folding and maturation by catalyzing the cis-trans isomerization of proline residues. 2. **Calcium signaling**: FKBP1A interacts with calcineurin to regulate calcium signaling pathways, which are essential for the proper functioning of the immune system and cellular homeostasis. 3. **Immune response regulation**: FKBP1A modulates the activity of various signaling pathways, including the NF-κB and TGF-β pathways, to regulate the immune response. 4. **Cellular homeostasis**: FKBP1A plays a crucial role in maintaining cellular homeostasis by regulating protein folding, calcium signaling, and immune response. **Clinical Significance** FKBP1A has significant clinical implications, particularly in the context of immune-mediated disorders and cancer. Abnormalities in FKBP1A expression or function have been implicated in various diseases, including: 1. **Autoimmune disorders**: FKBP1A plays a crucial role in regulating the immune response, and abnormalities in FKBP1A expression or function have been implicated in autoimmune disorders such as rheumatoid arthritis and lupus. 2. **Cancer**: FKBP1A is involved in the regulation of cell growth and proliferation, and abnormalities in FKBP1A expression or function have been implicated in various types of cancer, including breast cancer and lung cancer. 3. **Infectious diseases**: FKBP1A plays a crucial role in regulating the immune response to viral infections, and abnormalities in FKBP1A expression or function have been implicated in various infectious diseases, including COVID-19. In conclusion, FKBP1A is a critical regulator of immune response and cellular homeostasis, and its dysregulation has significant clinical implications. Further research is needed to fully understand the role of FKBP1A in various diseases and to develop therapeutic strategies to target this protein.

Genular Protein ID: 2404836209

Symbol: FKB1A_HUMAN

Name: Peptidyl-prolyl cis-trans isomerase FKBP1A

UniProtKB Accession Codes:

P62942 D3DVW6 P20071 Q4VC47 Q6FGD9 Q6LEU3 Q9H103 Q9H566

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 DrugBank 15 DrugCentral 1 EC 1 EMBL 17 EMDB 11 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 40 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 83 PDBsum 83 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 7 RefSeq 2 Rhea 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1695378

Title: Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin.

PubMed ID: 1695378

DOI: 10.1073/pnas.87.14.5440

PubMed ID: 1696686

Title: Molecular cloning and overexpression of the human FK506-binding protein FKBP.

PubMed ID: 1696686

DOI: 10.1038/346671a0

PubMed ID: 1716149

Title: Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains.

PubMed ID: 1716149

DOI: 10.1021/bi00099a002

PubMed ID: 7529739

Title: Three distinct messenger RNAs can encode the human immunosuppressant-binding protein FKBP12.

PubMed ID: 7529739

DOI: 10.1016/0378-1119(94)90434-0

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1701173

Title: The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase.

PubMed ID: 1701173

DOI: 10.1016/s0021-9258(17)45319-1

PubMed ID: 2477715

Title: A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase.

PubMed ID: 2477715

DOI: 10.1038/341758a0

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 8955134

Title: FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin.

PubMed ID: 8955134

DOI: 10.1074/jbc.271.51.32923

PubMed ID: 9233797

Title: Mechanism of TGFbeta receptor inhibition by FKBP12.

PubMed ID: 9233797

DOI: 10.1093/emboj/16.13.3866

PubMed ID: 10358090

Title: Further characterization of the type 3 ryanodine receptor (RyR3) purified from rabbit diaphragm.

PubMed ID: 10358090

DOI: 10.1074/jbc.274.24.17297

PubMed ID: 16720724

Title: FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor.

PubMed ID: 16720724

DOI: 10.1677/jme.1.01966

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22100703

Title: Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

PubMed ID: 22100703

DOI: 10.1016/j.abb.2011.11.004

PubMed ID: 1709363

Title: Proton and nitrogen sequential assignments and secondary structure determination of the human FK506 and rapamycin binding protein.

PubMed ID: 1709363

DOI: 10.1021/bi00233a020

PubMed ID: 1709301

Title: Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.

PubMed ID: 1709301

DOI: 10.1126/science.1709301

PubMed ID: 1375171

Title: Solution structure of FK506 bound to FKBP-12.

PubMed ID: 1375171

DOI: 10.1016/0014-5793(92)80292-o

PubMed ID: 7682113

Title: 1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin.

PubMed ID: 7682113

DOI: 10.1002/bip.360330404

PubMed ID: 1709302

Title: Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.

PubMed ID: 1709302

DOI: 10.1126/science.1709302

PubMed ID: 7678431

Title: Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin.

PubMed ID: 7678431

DOI: 10.1006/jmbi.1993.1012

PubMed ID: 10025408

Title: Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12.

PubMed ID: 10025408

DOI: 10.1016/s0092-8674(00)80555-3

PubMed ID: 10656803

Title: X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.

PubMed ID: 10656803

DOI: 10.1006/jmbi.1999.3411

Sequence Information:

  • Length: 108
  • Mass: 11951
  • Checksum: 9CC8493C802540B4
  • Sequence:
    • MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW 
EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

Genular Protein ID: 1616946723

Symbol: Q0VDC6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q0VDC6

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 2 Gene3D 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 PharmGKB 1 RefSeq 1 Rhea 3 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 145
  • Mass: 15689
  • Checksum: DFB0CDCB1F74A847
  • Sequence:
    • MGRQRAEGLG RAVEPPPGRC WSTPPVAPPA RSASAAAMGV QVETISPGDG RTFPKRGQTC 
VVHYTGMLED GKKFDSSRDR NKPFKFMLGK QEVIRGWEEG VAQMSVGQRA KLTISPDYAY 
GATGHPGIIP PHATLVFDVE LLKLE

Genular Protein ID: 623162252

Symbol: A0A087WTS4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WTS4

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GeneTree 1 HGNC 1 HOGENOM 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 Proteomes 2 RefSeq 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 97
  • Mass: 10800
  • Checksum: 508EAC10C43E54BA
  • Sequence:
    • MGVQVETISP GDGRTFPKRG QTCVVHYTDE CGSESQTDYI SRLCLWCHWA PRHHPTTCHS 
RLRCGASKTG MTGMASSLSS LFLDLPWRDL VPPDMCT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.